Catalog No.
PMF79001
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse HSPG2 (Asp4190-Ser4383).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Perlecan (heparan sulfate proteoglycan 2), Hspg2
Purification
Purified by antigen affinity column.
Accession
E9PZ16
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice., PMID:40320111
Recognition of Tumor Nidogen-1 by Neutrophil C-Type Lectin Receptors., PMID:35453656
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans., PMID:34433968
MicroRNA-197-3p mediates damage to human coronary artery endothelial cells via targeting TIMP3 in Kawasaki disease., PMID:34351574
Cleavage of the Perlecan-Semaphorin 3A-Plexin A1-Neuropilin-1 (PSPN) Complex by Matrix Metalloproteinase 7/Matrilysin Triggers Prostate Cancer Cell Dyscohesion and Migration., PMID:33809984
Genetic Factors in Antiphospholipid Syndrome: Preliminary Experience with Whole Exome Sequencing., PMID:33333988
Secretome Analysis Performed During in vitro Cardiac Differentiation: Discovering the Cardiac Microenvironment., PMID:32117977
Discovery of HSPG2 (Perlecan) as a Therapeutic Target in Triple Negative Breast Cancer., PMID:31462656
Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells., PMID:29740048
The heparan sulphate deficient Hspg2 exon 3 null mouse displays reduced deposition of TGF-β1 in skin compared to C57BL/6 wild type mice., PMID:27098652
Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways., PMID:26517691
Different expression patterns of PRRSV mediator genes in the lung tissues of PRRSV resistant and susceptible pigs., PMID:22305867
Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation., PMID:18589009
A novel peptide sequence in perlecan domain IV supports cell adhesion, spreading and FAK activation., PMID:17997086
Sid4: A secreted vertebrate immunoglobulin protein with roles in zebrafish embryogenesis., PMID:15936329
Heparan sulfate of perlecan is involved in glomerular filtration., PMID:15872080
Dyssegmental dysplasia, Silverman-Handmaker type, is caused by functional null mutations of the perlecan gene., PMID:11279527
Immunolocalization of a fibronectin-binding proteoglycan (PG-P1) immunologically related to HSPG2/perlecan in normal and fibrotic human liver., PMID:7814795
Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor., PMID:1569102
For research use only. Not for human or drug use.
