Catalog No.
PMD42701
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse EFNA1 (Met1-Ser182).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) [Cleaved into: Ephrin-A1, secreted form]
Purification
Purified by antigen affinity column.
Accession
P52793
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Development of an anti-human EphA2 monoclonal antibody Ea2Mab-7 for multiple applications., PMID:40236294
Effectiveness of anti-erythropoietin producing Hepatocellular receptor Type-A2 antibody in pancreatic cancer treatment., PMID:38034633
The role of EphA2 in ADAM17- and ionizing radiation-enhanced lung cancer cell migration., PMID:36998455
May EPH/Ephrin Targeting Revolutionize Lung Cancer Treatment?, PMID:36613532
Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance., PMID:36401637
Quantitative Tyrosine Phosphoproteomic Analysis of Resistance to Radiotherapy in Nasopharyngeal Carcinoma Cells., PMID:33328764
EphrinA1-Fc Attenuates Ventricular Remodeling and Dysfunction in Chronically Nonreperfused WT but not EphA2-R-M mice., PMID:32823610
Targeting EphA2 in cancer., PMID:32811512
Analysis of GPI-Anchored Receptor Distribution and Dynamics in Live Cells by Tag-mediated Enzymatic Labeling and FRET., PMID:32349461
Use of Multifactorial Treatments to Address the Challenge of Translating Experimental Myocardial Infarct Reduction Strategies., PMID:30909376
Eph/ephrin signalling serves a bidirectional role in lipopolysaccharide‑induced intestinal injury., PMID:29901151
An Agonistic Antibody to EPHA2 Exhibits Antitumor Effects on Human Melanoma Cells., PMID:29848674
A potential role for Eph receptor signalling during migration of corneal endothelial cells., PMID:29476773
Molecular and functional crosstalk between extracellular Hsp90 and ephrin A1 signaling., PMID:29290990
EphrinA1-Fc attenuates myocardial ischemia/reperfusion injury in mice., PMID:29236774
Erythropoietin-Producing Hepatoma Receptor Tyrosine Kinase A2 Modulation Associates with Protective Effect of Prone Position in Ventilator-induced Lung Injury., PMID:29216437
EphA2 receptor activation with ephrin-A1 ligand restores cetuximab efficacy in NRAS-mutant colorectal cancer cells., PMID:28560458
Protection by the Eph-Ephrin System Against Mesenteric Ischemia-Reperfusion Injury., PMID:28472014
Inhibition of EphA2/EphrinA1 signal attenuates lipopolysaccharide-induced lung injury., PMID:27549114
A Microbead Supported Membrane-Based Fluorescence Imaging Assay Reveals Intermembrane Receptor-Ligand Complex Dimension with Nanometer Precision., PMID:27264296
A novel bispecific immunotoxin delivered by human bone marrow-derived mesenchymal stem cells to target blood vessels and vasculogenic mimicry of malignant gliomas., PMID:26089644
Treatment of Dutch rat models of glioma using EphrinA1-PE38/GM-CSF chitosan nanoparticles by in situ activation of dendritic cells., PMID:25957892
ADAM12-cleaved ephrin-A1 contributes to lung metastasis., PMID:23686306
Ephrin-A1-mediated dopaminergic neurogenesis and angiogenesis in a rat model of Parkinson's disease., PMID:22363788
EphA2 receptor activation by monomeric Ephrin-A1 on supported membranes., PMID:22261062
Activation of erythropoietin-producing hepatocellular receptor A2 attenuates cell adhesion of human fallopian tube epithelial cells via focal adhesion kinase dephosphorylation., PMID:22009484
Intramyocardial administration of chimeric ephrinA1-Fc promotes tissue salvage following myocardial infarction in mice., PMID:21282286
Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1., PMID:20861311
Structure-activity relationship analysis of peptides targeting the EphA2 receptor., PMID:20677833
Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer., PMID:20130824
Selective removal of ovarian cancer cells from human ascites fluid using magnetic nanoparticles., PMID:19969103
EphA2 receptor mediates increased vascular permeability in lung injury due to viral infection and hypoxia., PMID:19684201
Synthetic biomimetic hydrogels incorporated with ephrin-A1 for therapeutic angiogenesis., PMID:17206786
Silencing the receptor EphA2 suppresses the growth and haptotaxis of malignant mesothelioma cells., PMID:17041885
EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes., PMID:16547242
Trans-activation of EphA4 and FGF receptors mediated by direct interactions between their cytoplasmic domains., PMID:16365308
Giant cell tumors of the bone: molecular profiling and expression analysis of Ephrin A1 receptor, Claudin 7, CD52, FGFR3 and AMFR., PMID:16325507
EphA2 as a novel molecular marker and target in glioblastoma multiforme., PMID:16254188
Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection., PMID:15681844
Ligation of EphA2 by Ephrin A1-Fc inhibits pancreatic adenocarcinoma cellular invasiveness., PMID:15249202
Ephrin-A1 suppresses Th2 cell activation and provides a regulatory link to lung epithelial cells., PMID:14707054
EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells., PMID:12775584
Independent prognostic impact of lymphatic vessel density and presence of low-grade lymphangiogenesis in cutaneous melanoma., PMID:12538477
c-Cbl-dependent EphA2 protein degradation is induced by ligand binding., PMID:12496371
EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma., PMID:12494475
Expression and function of the Eph A receptors and their ligands ephrins A in the rat thymus., PMID:12077243
Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK- and SAPK/JNK-dependent but nuclear factor-kappa B-independent mechanism., PMID:11278471
The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization., PMID:11146556
Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis., PMID:7536959
Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity., PMID:7973638
For research use only. Not for human or drug use.
