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Anti-Mouse IL1RN/IL-1ra/IL1F3 Polyclonal Antibody

Catalog #:   PMD29701 Specific References (100) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q542W1
Overview

Catalog No.

PMD29701

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse IL1RN/IL-1ra/IL1F3 (Arg8-Gln159).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Interleukin-1, Il1rn

Purification

Purified by antigen affinity column.

Accession

Q542W1

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with IL1RN/IL-1ra/IL1F3 antibody (PMD29701) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 20 kDa
    Observed MW: 20 kDa
References

Transcriptome analysis of renal ischemia/reperfusion (I/R) injury in BAFF and BAFF-R deficient mice., PMID:37751458

Transcriptome analysis of renal ischemia/reperfusion (I/R) injury in BAFF and BAFF-R deficient mice., PMID:37751458

Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation., PMID:36596811

Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation., PMID:36596811

Immunologic profiling in schizophrenia and rheumatoid arthritis., PMID:36058039

Immunologic profiling in schizophrenia and rheumatoid arthritis., PMID:36058039

Canakinumab treatment in a young girl with refractory chronic recurrent multifocal osteomyelitis associated with pyoderma gangrenosum., PMID:36004431

Canakinumab treatment in a young girl with refractory chronic recurrent multifocal osteomyelitis associated with pyoderma gangrenosum., PMID:36004431

Expression-based Genome-wide Association Study Links OPN and IL1-RA With Newly Diagnosed Type 1 Diabetes in Children., PMID:35460250

Expression-based Genome-wide Association Study Links OPN and IL1-RA With Newly Diagnosed Type 1 Diabetes in Children., PMID:35460250

Evaluation of Serum Interleukin-38 Levels in Different Radiographic Grades of Idiopathic Knee Osteoarthritis., PMID:34788133

Evaluation of Serum Interleukin-38 Levels in Different Radiographic Grades of Idiopathic Knee Osteoarthritis., PMID:34788133

Blocking of interleukin-1 suppresses angiotensin II-induced renal injury., PMID:34402864

Blocking of interleukin-1 suppresses angiotensin II-induced renal injury., PMID:34402864

Perspectives on anti-IL-1 inhibitors as potential therapeutic interventions for severe COVID-19., PMID:33926774

Perspectives on anti-IL-1 inhibitors as potential therapeutic interventions for severe COVID-19., PMID:33926774

Experimental modulation of Interleukin 1 shows its key role in chronic kidney disease progression and anemia., PMID:33737665

Experimental modulation of Interleukin 1 shows its key role in chronic kidney disease progression and anemia., PMID:33737665

Distinct Gene Expression Signatures Characterize Strong Clinical Responders Versus Nonresponders to Canakinumab in Children With Systemic Juvenile Idiopathic Arthritis., PMID:33452871

Distinct Gene Expression Signatures Characterize Strong Clinical Responders Versus Nonresponders to Canakinumab in Children With Systemic Juvenile Idiopathic Arthritis., PMID:33452871

Serum IL-1RA levels increase from follicular to luteal phase of the ovarian cycle: A pilot study on human female immune responses., PMID:32881904

Serum IL-1RA levels increase from follicular to luteal phase of the ovarian cycle: A pilot study on human female immune responses., PMID:32881904

A case report of a novel compound heterozygous mutation in a Brazilian patient with deficiency of Interleukin-1 receptor antagonist (DIRA)., PMID:32819369

A case report of a novel compound heterozygous mutation in a Brazilian patient with deficiency of Interleukin-1 receptor antagonist (DIRA)., PMID:32819369

New variant in the IL1RN-gene (DIRA) associated with late-onset, CRMO-like presentation., PMID:32259833

New variant in the IL1RN-gene (DIRA) associated with late-onset, CRMO-like presentation., PMID:32259833

Tumor-infiltrating Leukocytes Suppress Local Inflammation Via Interleukin-1 Receptor Antagonist in a Syngeneic Prostate Cancer Model., PMID:32244522

Tumor-infiltrating Leukocytes Suppress Local Inflammation Via Interleukin-1 Receptor Antagonist in a Syngeneic Prostate Cancer Model., PMID:32244522

Emerging Approaches for Regulation and Control of CAR T Cells: A Mini Review., PMID:32194561

Emerging Approaches for Regulation and Control of CAR T Cells: A Mini Review., PMID:32194561

The role of Toll-like receptor 10 in modulation of trained immunity., PMID:31671203

The role of Toll-like receptor 10 in modulation of trained immunity., PMID:31671203

Evaluation of changes in expression pattern of oxidative stress genes under the influence of adalimumab., PMID:31664747

Evaluation of changes in expression pattern of oxidative stress genes under the influence of adalimumab., PMID:31664747

Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra., PMID:31611644

Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra., PMID:31611644

Impact of IL1RN Variants on Response to Interleukin-1 Blocking Therapy in Systemic Juvenile Idiopathic Arthritis., PMID:31599092

Impact of IL1RN Variants on Response to Interleukin-1 Blocking Therapy in Systemic Juvenile Idiopathic Arthritis., PMID:31599092

Deficiency of Interleukin-1 Receptor Antagonist: A Case with Late Onset Severe Inflammatory Arthritis, Nail Psoriasis with Onychomycosis and Well Responsive to Adalimumab Therapy., PMID:31467740

Deficiency of Interleukin-1 Receptor Antagonist: A Case with Late Onset Severe Inflammatory Arthritis, Nail Psoriasis with Onychomycosis and Well Responsive to Adalimumab Therapy., PMID:31467740

Long-term therapy with anakinra in hidradenitis suppurativa in three patients., PMID:31353451

Long-term therapy with anakinra in hidradenitis suppurativa in three patients., PMID:31353451

Whole exome sequencing approach to childhood onset familial erythrodermic psoriasis unravels a novel mutation of CARD14 requiring unusual high doses of ustekinumab., PMID:31286971

Whole exome sequencing approach to childhood onset familial erythrodermic psoriasis unravels a novel mutation of CARD14 requiring unusual high doses of ustekinumab., PMID:31286971

Combination of G-CSF and AMD3100 Improves the Anti-inflammatory Effect of Mesenchymal Stem Cells on Inducing M2 Polarization of Macrophages Through NF-κB-IL1RA Signaling Pathway., PMID:31191315

Combination of G-CSF and AMD3100 Improves the Anti-inflammatory Effect of Mesenchymal Stem Cells on Inducing M2 Polarization of Macrophages Through NF-κB-IL1RA Signaling Pathway., PMID:31191315

Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals., PMID:31077280

Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals., PMID:31077280

Keratinocyte Integrin α3β1 Promotes Secretion of IL-1α to Effect Paracrine Regulation of Fibroblast Gene Expression and Differentiation., PMID:30878678

Keratinocyte Integrin α3β1 Promotes Secretion of IL-1α to Effect Paracrine Regulation of Fibroblast Gene Expression and Differentiation., PMID:30878678

Gene Expression Pathways across Multiple Tissues in Antineutrophil Cytoplasmic Antibody-associated Vasculitis Reveal Core Pathways of Disease Pathology., PMID:30647166

Gene Expression Pathways across Multiple Tissues in Antineutrophil Cytoplasmic Antibody-associated Vasculitis Reveal Core Pathways of Disease Pathology., PMID:30647166

Adults with septic shock and extreme hyperferritinemia exhibit pathogenic immune variation., PMID:29977033

Adults with septic shock and extreme hyperferritinemia exhibit pathogenic immune variation., PMID:29977033

Inhibition of interleukin-1 suppresses angiotensin II-induced aortic inflammation and aneurysm formation., PMID:29884291

Inhibition of interleukin-1 suppresses angiotensin II-induced aortic inflammation and aneurysm formation., PMID:29884291

Deficiency of IL-1 receptor antagonist suppresses IL-10-producing B cells in autoimmune arthritis in an IL-17/Th17-dependent manner., PMID:29803636

Deficiency of IL-1 receptor antagonist suppresses IL-10-producing B cells in autoimmune arthritis in an IL-17/Th17-dependent manner., PMID:29803636

VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes., PMID:29216931

VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes., PMID:29216931

IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas., PMID:28330899

IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas., PMID:28330899

Enhanced delivery of IL-1 receptor antagonist to the central nervous system as a novel anti-transferrin receptor-IL-1RA fusion reverses neuropathic mechanical hypersensitivity., PMID:28009628

Enhanced delivery of IL-1 receptor antagonist to the central nervous system as a novel anti-transferrin receptor-IL-1RA fusion reverses neuropathic mechanical hypersensitivity., PMID:28009628

Intracellular Chloride Concentration Changes Modulate IL-1β Expression and Secretion in Human Bronchial Epithelial Cultured Cells., PMID:27996167

Intracellular Chloride Concentration Changes Modulate IL-1β Expression and Secretion in Human Bronchial Epithelial Cultured Cells., PMID:27996167

Cytokine response to Hantaan virus infection in patients with hemorrhagic fever with renal syndrome., PMID:27943332

Cytokine response to Hantaan virus infection in patients with hemorrhagic fever with renal syndrome., PMID:27943332

Inverse Relationship Between Organ-Specific Autoantibodies and Systemic Immune Mediators in Type 1 Diabetes and Type 2 Diabetes: Action LADA 11., PMID:27573939

Inverse Relationship Between Organ-Specific Autoantibodies and Systemic Immune Mediators in Type 1 Diabetes and Type 2 Diabetes: Action LADA 11., PMID:27573939

Mucosal immunity and upper respiratory tract infections during a 24-week competitive season in young ice hockey players., PMID:27540695

Mucosal immunity and upper respiratory tract infections during a 24-week competitive season in young ice hockey players., PMID:27540695

The leishmanicidal activity of oleuropein is selectively regulated through inflammation- and oxidative stress-related genes., PMID:27501956

The leishmanicidal activity of oleuropein is selectively regulated through inflammation- and oxidative stress-related genes., PMID:27501956

Autoantibody-Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity., PMID:27059145

Autoantibody-Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity., PMID:27059145

Reconstitution of ST2 (IL-1R4) specific for IL-33 activity; no suppression by IL-1Ra though a common chain IL-1R3 (IL-1RAcP) shared with IL-1., PMID:27031441

Reconstitution of ST2 (IL-1R4) specific for IL-33 activity; no suppression by IL-1Ra though a common chain IL-1R3 (IL-1RAcP) shared with IL-1., PMID:27031441

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis., PMID:26972847

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis., PMID:26972847

Associations between interleukin-1 polymorphisms and susceptibility to vasculitis: a meta-analysis., PMID:26695178

Associations between interleukin-1 polymorphisms and susceptibility to vasculitis: a meta-analysis., PMID:26695178

Interleukin-1 Receptor Antagonist Has a Novel Function in the Regulation of Matrix Metalloproteinase-13 Expression., PMID:26474296

Interleukin-1 Receptor Antagonist Has a Novel Function in the Regulation of Matrix Metalloproteinase-13 Expression., PMID:26474296

The role of inflammation in intravenous immune globulin-mediated hemolysis., PMID:26174900

The role of inflammation in intravenous immune globulin-mediated hemolysis., PMID:26174900

Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra., PMID:26174021

Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra., PMID:26174021

TACI deficiency leads to alternatively activated macrophage phenotype and susceptibility to Leishmania infection., PMID:26170307

TACI deficiency leads to alternatively activated macrophage phenotype and susceptibility to Leishmania infection., PMID:26170307

Interleukin-1 receptor antagonist deficiency with a novel mutation; late onset and successful treatment with canakinumab: a case report., PMID:26100510

Interleukin-1 receptor antagonist deficiency with a novel mutation; late onset and successful treatment with canakinumab: a case report., PMID:26100510

Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models., PMID:26047123

Oral administration of bovine milk derived extracellular vesicles attenuates arthritis in two mouse models., PMID:26047123

Tumor necrosis factor mediates temporomandibular joint bone tissue resorption in rheumatoid arthritis., PMID:25515682

Tumor necrosis factor mediates temporomandibular joint bone tissue resorption in rheumatoid arthritis., PMID:25515682

Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes., PMID:24918199

Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes., PMID:24918199

Efficacy and safety implications of molecular constructs of biological agents for rheumatoid arthritis., PMID:24720727

Efficacy and safety implications of molecular constructs of biological agents for rheumatoid arthritis., PMID:24720727

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Mouse IL1RN/IL-1ra/IL1F3 Polyclonal Antibody [PMD29701]
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