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Anti-Mouse CD117/KIT Polyclonal Antibody

Catalog #:   PMC83101 Specific References (100) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P05532
Overview

Catalog No.

PMC83101

Species reactivity

Mouse

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD117/KIT (Ser38-Gly513).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)

Purification

Purified by antigen affinity column.

Accession

P05532

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CD117/KIT antibody (PMC83101) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 55 kDa
    Observed MW: 55 kDa
References

Effects of C3aR activated mast cells in eosinophilic esophagitis., PMID:40502038

Effects of C3aR activated mast cells in eosinophilic esophagitis., PMID:40502038

The cytotoxic effect of quercetin-induced apoptosis on lung metastatic cells from giant cell tumor of bone., PMID:40418557

The cytotoxic effect of quercetin-induced apoptosis on lung metastatic cells from giant cell tumor of bone., PMID:40418557

Targeting KIT With Antibody-Drug Conjugates in Chromophobe Renal Cell Carcinoma., PMID:40408838

Targeting KIT With Antibody-Drug Conjugates in Chromophobe Renal Cell Carcinoma., PMID:40408838

Navigating Ongoing Challenges in GI Stromal Tumors., PMID:40393024

Navigating Ongoing Challenges in GI Stromal Tumors., PMID:40393024

Pathology Seen in Myenteric Plexus in Two Subjects With Waardenburg Syndrome., PMID:40364458

Pathology Seen in Myenteric Plexus in Two Subjects With Waardenburg Syndrome., PMID:40364458

Multiplex immunophenotyping of human acute myeloid leukemia patients revealed single -cell heterogeneity with special attention on therapy sensitive and therapy resistant subpopulations., PMID:40313947

Multiplex immunophenotyping of human acute myeloid leukemia patients revealed single -cell heterogeneity with special attention on therapy sensitive and therapy resistant subpopulations., PMID:40313947

Functional roles of interstitial cells of Cajal in the GI tract of rats., PMID:40235202

Functional roles of interstitial cells of Cajal in the GI tract of rats., PMID:40235202

[Indolent systemic mastocytosis : an overview in 2025]., PMID:40176613

[Indolent systemic mastocytosis : an overview in 2025]., PMID:40176613

Cold-induced anaphylaxis: new insights into clinical and genetic characteristics., PMID:40061949

Cold-induced anaphylaxis: new insights into clinical and genetic characteristics., PMID:40061949

First Report of Pembrolizumab Activity in KIT-Mutated Thymic Carcinoma., PMID:39996868

First Report of Pembrolizumab Activity in KIT-Mutated Thymic Carcinoma., PMID:39996868

Immunohistochemical analysis of 147 cases of low-grade endometrial stromal sarcoma: refining the immunohistochemical profile of LG-ESS on a large, molecularly confirmed series., PMID:39836188

Immunohistochemical analysis of 147 cases of low-grade endometrial stromal sarcoma: refining the immunohistochemical profile of LG-ESS on a large, molecularly confirmed series., PMID:39836188

Histologic, histochemical, and immunohistochemical changes in buffalo liver with cystic echinococcosis., PMID:39757763

Histologic, histochemical, and immunohistochemical changes in buffalo liver with cystic echinococcosis., PMID:39757763

KIRA6 is an Effective and Versatile Mast Cell Inhibitor of IgE-mediated Activation., PMID:39676406

KIRA6 is an Effective and Versatile Mast Cell Inhibitor of IgE-mediated Activation., PMID:39676406

Mechanisms of reduced sensitization by extensive hydrolysis of milk protein concentrate: Impact on the immune response of Th1/Th2 and Treg/Th17 cells in mice., PMID:39662801

Mechanisms of reduced sensitization by extensive hydrolysis of milk protein concentrate: Impact on the immune response of Th1/Th2 and Treg/Th17 cells in mice., PMID:39662801

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA., PMID:39656107

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA., PMID:39656107

Gene Expression Profiling of the Peritumoral Immune Cell Infiltrate of Penile Squamous Cell Carcinomas., PMID:39596210

Gene Expression Profiling of the Peritumoral Immune Cell Infiltrate of Penile Squamous Cell Carcinomas., PMID:39596210

A single-chain variable fragment-based bispecific T-cell activating antibody against CD117 enables T-cell mediated lysis of acute myeloid leukemia and hematopoietic stem and progenitor cells., PMID:39564539

A single-chain variable fragment-based bispecific T-cell activating antibody against CD117 enables T-cell mediated lysis of acute myeloid leukemia and hematopoietic stem and progenitor cells., PMID:39564539

Novel Insights Into the Ultrastructural and Immunofluorescence Characteristics of Limb Skin in the Red-Eared Slider Turtle (Trachemys scripta elegans)., PMID:39508632

Novel Insights Into the Ultrastructural and Immunofluorescence Characteristics of Limb Skin in the Red-Eared Slider Turtle (Trachemys scripta elegans)., PMID:39508632

Investigating the effect of immunomagnetic separation on the immunophenotype and viability of plasma cells in plasma cell disorders., PMID:39493694

Investigating the effect of immunomagnetic separation on the immunophenotype and viability of plasma cells in plasma cell disorders., PMID:39493694

Targeted hematopoietic stem cell depletion through SCF-blockade., PMID:39473008

Targeted hematopoietic stem cell depletion through SCF-blockade., PMID:39473008

Gastrointestinal Stromal Tumors: Variants and Some Pitfalls That They Create., PMID:39466697

Gastrointestinal Stromal Tumors: Variants and Some Pitfalls That They Create., PMID:39466697

Role of Interstitial Cells of Cajal in Congenital Ureteropelvic Junction Obstruction., PMID:39316030

Role of Interstitial Cells of Cajal in Congenital Ureteropelvic Junction Obstruction., PMID:39316030

Immunohistochemical Analysis of CD117 in the Mast Cells of Odontogenic Keratocysts., PMID:39310512

Immunohistochemical Analysis of CD117 in the Mast Cells of Odontogenic Keratocysts., PMID:39310512

C-Kit Immunohistochemical Expression as a Complementary Method to Assess Mast Cell Density in Helicobacter pylori-Mediated Gastritis., PMID:39278202

C-Kit Immunohistochemical Expression as a Complementary Method to Assess Mast Cell Density in Helicobacter pylori-Mediated Gastritis., PMID:39278202

A significant difference of synovial mast cells in synovium from rotator cuff arthropathy compared to rotator cuff tears: A histological pilot study., PMID:39156865

A significant difference of synovial mast cells in synovium from rotator cuff arthropathy compared to rotator cuff tears: A histological pilot study., PMID:39156865

NOTCH1- and CD117-Positive Stem Cells in Human Endometriosis and Adenomyosis Lesions., PMID:39125516

NOTCH1- and CD117-Positive Stem Cells in Human Endometriosis and Adenomyosis Lesions., PMID:39125516

The prognostic significance of CD117-positive mast cells and microvessel density in colorectal cancer., PMID:39029054

The prognostic significance of CD117-positive mast cells and microvessel density in colorectal cancer., PMID:39029054

Unusual PEComa With PRCC :: TFE3 Fusion Mimicking Sinonasal Tract Melanoma., PMID:38975712

Unusual PEComa With PRCC :: TFE3 Fusion Mimicking Sinonasal Tract Melanoma., PMID:38975712

Clinicopathological differences between T-lymphoblastic leukemia/lymphoma, early T-precursor lymphoblastic leukemia/lymphoma, and mixed-phenotype acute leukemia with T lineage: An analysis of 41 adult cases., PMID:38945375

Clinicopathological differences between T-lymphoblastic leukemia/lymphoma, early T-precursor lymphoblastic leukemia/lymphoma, and mixed-phenotype acute leukemia with T lineage: An analysis of 41 adult cases., PMID:38945375

An optimized method for IgE-mediated degranulation of human lung mast cells., PMID:38881896

An optimized method for IgE-mediated degranulation of human lung mast cells., PMID:38881896

Measurable Residual Disease Analysis by Flow Cytometry and Correlation With Molecular Measurable Residual Disease in Acute Promyelocytic Leukemia: A Real-World Prospective Study., PMID:38838353

Measurable Residual Disease Analysis by Flow Cytometry and Correlation With Molecular Measurable Residual Disease in Acute Promyelocytic Leukemia: A Real-World Prospective Study., PMID:38838353

Usefulness of antibody-drug conjugate as preconditioning for hematopoietic stem cell-targeted gene therapy in wild-type and Fabry disease mouse models., PMID:38820907

Usefulness of antibody-drug conjugate as preconditioning for hematopoietic stem cell-targeted gene therapy in wild-type and Fabry disease mouse models., PMID:38820907

Flow cytometric immunophenotypic differentiation patterns of bone marrow eosinophilopoiesis., PMID:38666394

Flow cytometric immunophenotypic differentiation patterns of bone marrow eosinophilopoiesis., PMID:38666394

Lin-CD117+CD34+FcεRI+ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti-IgE therapy., PMID:38634175

Lin-CD117+CD34+FcεRI+ progenitor cells are increased in chronic spontaneous urticaria and predict clinical responsiveness to anti-IgE therapy., PMID:38634175

Clinical, Epidemiological, Morphological, and Immunohistochemical Aspects of Nasopharyngeal Carcinoma-4-Year Retrospective Study in the Western Part of Romania., PMID:38611634

Clinical, Epidemiological, Morphological, and Immunohistochemical Aspects of Nasopharyngeal Carcinoma-4-Year Retrospective Study in the Western Part of Romania., PMID:38611634

Hematopoiesis after anti-CD117 monoclonal antibody treatment in the settings of wild-type and Fanconi anemia mice., PMID:38572555

Hematopoiesis after anti-CD117 monoclonal antibody treatment in the settings of wild-type and Fanconi anemia mice., PMID:38572555

Immunophenotypic characterization of leukemic stem cells in acute myeloid leukemia using single tube 10-colour panel by multiparametric flow cytometry: Deciphering the spectrum, complexity and immunophenotypic heterogeneity., PMID:38456256

Immunophenotypic characterization of leukemic stem cells in acute myeloid leukemia using single tube 10-colour panel by multiparametric flow cytometry: Deciphering the spectrum, complexity and immunophenotypic heterogeneity., PMID:38456256

Myxoma Virus Combination Therapy Enhances Lenalidomide and Bortezomib Treatments for Multiple Myeloma., PMID:38251379

Myxoma Virus Combination Therapy Enhances Lenalidomide and Bortezomib Treatments for Multiple Myeloma., PMID:38251379

Regulation of mast cells by overlapping but distinct protein interactions of Siglec-6 and Siglec-8., PMID:38186079

Regulation of mast cells by overlapping but distinct protein interactions of Siglec-6 and Siglec-8., PMID:38186079

Development of a flow cytometric panel to assess prognostic biomarkers in fine needle aspirates of canine cutaneous or subcutaneous mast cell tumors., PMID:38076567

Development of a flow cytometric panel to assess prognostic biomarkers in fine needle aspirates of canine cutaneous or subcutaneous mast cell tumors., PMID:38076567

Higher PD-1/Tim-3 expression on IFN-γ+ T cells is associated with poor prognosis in patients with acute myeloid leukemia., PMID:37962843

Higher PD-1/Tim-3 expression on IFN-γ+ T cells is associated with poor prognosis in patients with acute myeloid leukemia., PMID:37962843

Comparison of Mast Cell Density and Prognostic Factors in Invasive Breast Carcinoma: A Single-Centre Study in Malaysia., PMID:37928785

Comparison of Mast Cell Density and Prognostic Factors in Invasive Breast Carcinoma: A Single-Centre Study in Malaysia., PMID:37928785

Diagnostic Utility of EMA, Vimentin and CD117 Immunohistochemical Markers in Subtyping Renal Cell Carcinoma in a Nigerian Tertiary Hospital: A 10-year Retrospective Study., PMID:37906498

Diagnostic Utility of EMA, Vimentin and CD117 Immunohistochemical Markers in Subtyping Renal Cell Carcinoma in a Nigerian Tertiary Hospital: A 10-year Retrospective Study., PMID:37906498

Antibody-Based and Cell Therapies for Advanced Mastocytosis: Established and Novel Concepts., PMID:37894806

Antibody-Based and Cell Therapies for Advanced Mastocytosis: Established and Novel Concepts., PMID:37894806

[Morphological and molecular portrait hybrid renal tumors]., PMID:37850290

[Morphological and molecular portrait hybrid renal tumors]., PMID:37850290

Fertility-preserving myeloablative conditioning using single-dose CD117 antibody-drug conjugate in a rhesus gene therapy model., PMID:37828021

Fertility-preserving myeloablative conditioning using single-dose CD117 antibody-drug conjugate in a rhesus gene therapy model., PMID:37828021

Twenty-four-color full spectrum flow cytometry panel for minimal residual disease detection in acute myeloid leukemia., PMID:37533738

Twenty-four-color full spectrum flow cytometry panel for minimal residual disease detection in acute myeloid leukemia., PMID:37533738

Further explorations into the role of mast cells in deaths associated with fatal asphyxia: an immunohistochemical study utilizing CD 117 marker., PMID:37478731

Further explorations into the role of mast cells in deaths associated with fatal asphyxia: an immunohistochemical study utilizing CD 117 marker., PMID:37478731

Clinical and Laboratory Characteristics of IgM Primary Plasma Cell Leukemia., PMID:37436385

Clinical and Laboratory Characteristics of IgM Primary Plasma Cell Leukemia., PMID:37436385

Ureteropelvic junction obstruction in children by polar vessels: histological examination result., PMID:37254943

Ureteropelvic junction obstruction in children by polar vessels: histological examination result., PMID:37254943

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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Anti-Mouse CD117/KIT Polyclonal Antibody [PMC83101]
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