Catalog No.
PHK92401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ARID3A (Gly221-Arg351).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Bright, DRIL3, E2F-binding protein 1, ARID domain-containing protein 3A, ARID3A, DRX, E2FBP1, DRIL1, AT-rich interactive domain-containing protein 3A, B-cell regulator of IgH transcription, Dead ringer-like protein 1
Purification
Purified by antigen affinity column.
Accession
Q99856
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
H3K36 methyltransferase NSD1 is essential for normal B1 and B2 cell development and germinal center formation., PMID:36532012
Crucial Role of Increased Arid3a at the Pre-B and Immature B Cell Stages for B1a Cell Generation., PMID:30930899
Control of B-1a cell development by instructive BCR signaling., PMID:29414528
A Role for the Transcription Factor Arid3a in Mouse B2 Lymphocyte Expansion and Peritoneal B1a Generation., PMID:29114251
Antibody Reactivity of B Cells in Lupus Patients with Increased Disease Activity and ARID3a Expression., PMID:28580178
Differential expression of the transcription factor ARID3a in lupus patient hematopoietic progenitor cells., PMID:25535283
Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich-interactive domain 3A., PMID:25185498
The transcription factor Bright plays a role in marginal zone B lymphocyte development and autoantibody production., PMID:21963220
The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development., PMID:21199920
Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright., PMID:19214191
Transgenic mice expressing dominant-negative bright exhibit defects in B1 B cells., PMID:18981111
REKLES is an ARID3-restricted multifunctional domain., PMID:17400556
Bright/ARID3A contributes to chromatin accessibility of the immunoglobulin heavy chain enhancer., PMID:17386101
Anti-nuclear antibody production and autoimmunity in transgenic mice that overexpress the transcription factor Bright., PMID:17312145
Induction of immunoglobulin heavy-chain transcription through the transcription factor Bright requires TFII-I., PMID:16738337
A regulated nucleocytoplasmic shuttle contributes to Bright's function as a transcriptional activator of immunoglobulin genes., PMID:16507996
Bruton's tyrosine kinase regulates immunoglobulin promoter activation in association with the transcription factor Bright., PMID:15743806
Mutations in the DNA-binding domain of the transcription factor Bright act as dominant negative proteins and interfere with immunoglobulin transactivation., PMID:15456761
E2FBP1/hDril1 modulates cell growth through downregulation of promyelocytic leukemia bodies., PMID:15017387
High frequency of matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding sites flanking Ig V region genes., PMID:12193717
Transcriptional activation by a matrix associating region-binding protein. contextual requirements for the function of bright., PMID:11294836
Differential regulation of immunoglobulin gene transcription via nuclear matrix-associated regions., PMID:11232275
The transcription factor Bright associates with Bruton's tyrosine kinase, the defective protein in immunodeficiency disease., PMID:11120822
Regulation of matrix attachment region-dependent, lymphocyte-restricted transcription through differential localization within promyelocytic leukemia nuclear bodies., PMID:10921892
Cux/CDP homeoprotein is a component of NF-muNR and represses the immunoglobulin heavy chain intronic enhancer by antagonizing the bright transcription activator., PMID:9858552
A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer., PMID:9780002
The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family., PMID:8543152
For research use only. Not for human or drug use.
