Catalog No.
PHK89901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RAD18 (Gly12-Ser99).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
RAD18, RING finger protein 73, RNF73, hHR18, Postreplication repair protein RAD18, RING-type E3 ubiquitin transferase RAD18, E3 ubiquitin-protein ligase RAD18, hRAD18
Purification
Purified by antigen affinity column.
Accession
Q9NS91
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab., PMID:37557179
Transcriptional signatures associated with rubella virus-specific humoral immunity after a third dose of MMR vaccine in women of childbearing age., PMID:33818775
The functional status of DNA repair pathways determines the sensitization effect to cisplatin in non-small cell lung cancer cells., PMID:27473273
Cell Killing Mechanisms and Impact on Gene Expression by Gemcitabine and 212Pb-Trastuzumab Treatment in a Disseminated i.p. Tumor Model., PMID:27467592
Analysis of SHPRH functions in DNA repair and immunoglobulin diversification., PMID:25311267
The Rad6/18 ubiquitin complex interacts with the Epstein-Barr virus deubiquitinating enzyme, BPLF1, and contributes to virus infectivity., PMID:24672041
The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI., PMID:21355096
A role for PCNA ubiquitination in immunoglobulin hypermutation., PMID:17105346
Supramolecular complex formation between Rad6 and proteins of the p53 pathway during DNA damage-induced response., PMID:12640129
SMC proteins constitute two subunits of the mammalian recombination complex RC-1., PMID:8670910
Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites., PMID:7926769
For research use only. Not for human or drug use.
