Catalog No.
PHK88801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PHOX2B (Thr106-Gly173).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PMX2B, PHOX2B homeodomain protein, Paired-like homeobox 2B, Neuroblastoma Phox, Paired mesoderm homeobox protein 2B, NBPhox, PHOX2B
Purification
Purified by antigen affinity column.
Accession
Q99453
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
PHOX2B -associated Congenital Central Hypoventilation Syndrome Revealed Upon Treatment With Dinutuximab-beta., PMID:39961018
Euphorbia Pekinensis Rupr. sensitizes colorectal cancer to PD-1 blockade by remodeling the tumor microenvironment and enhancing peripheral immunity., PMID:39368338
Primitive Embryonic-Type Neuroectodermal/Glandular Complexes in Testicular Germ Cell Tumors: A Mimic of Embryonic-Type Neuroectodermal Tumor., PMID:38712621
Atomically accurate de novo design of antibodies with RFdiffusion., PMID:38562682
Temporal Expression of Hox Genes and Phox2b in the Rat Nucleus Ambiguus During Development: Implications on Laryngeal Innervation., PMID:37350386
Phox2B is a sensitive and reliable marker of paraganglioma-Phox2B immunohistochemistry in diagnosis of neuroendocrine neoplasms., PMID:36656393
Cauda equina neuroendocrine tumors show biological features distinct from other paragangliomas and visceral neuroendocrine tumors., PMID:36348031
Ganglion cell maturation in peripheral neuroblastic tumours of children., PMID:35142286
Probing the multimodal fungiform papilla: complex peripheral nerve endings of chorda tympani taste and mechanosensitive fibers before and after Hedgehog pathway inhibition., PMID:34859291
Cell non-autonomous requirement of p75 in the development of geniculate oral sensory neurons., PMID:33335119
Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action., PMID:31189118
Aldosterone-sensitive HSD2 neurons in mice., PMID:30343334
PHOX2B is a reliable immunomarker in distinguishing peripheral neuroblastic tumours from CNS embryonal tumours., PMID:29758594
PHOX2B reliably distinguishes neuroblastoma among small round blue cell tumours., PMID:28640941
Depletion of the IKBKAP ortholog in zebrafish leads to hirschsprung disease-like phenotype., PMID:25717236
Bone marrow minimal residual disease was an early response marker and a consistent independent predictor of survival after anti-GD2 immunotherapy., PMID:25559819
A study of gata3 and phox2b expression in tumors of the autonomic nervous system., PMID:23715162
Transcriptional dysregulation and impairment of PHOX2B auto-regulatory mechanism induced by polyalanine expansion mutations associated with congenital central hypoventilation syndrome., PMID:23103552
Developmental alterations of the respiratory human retrotrapezoid nucleus in sudden unexplained fetal and infant death., PMID:22796552
NK cytotoxicity and alloreactivity against neuroblastoma cell lines in vitro: comparison of Europium fluorometry assay and quantification by RT-PCR., PMID:22516232
Zebrafish: an exciting model for investigating the spatio-temporal pattern of enteric nervous system development., PMID:20972797
Novel neuropathologic findings in the Haddad syndrome., PMID:19844731
Signals from the neural crest regulate beta-cell mass in the pancreas., PMID:18506029
Generation of neuroendocrine chromaffin cells from sympathoadrenal progenitors: beyond the glucocorticoid hypothesis., PMID:12438182
A single rostrocaudal colonization of the rodent intestine by enteric neuron precursors is revealed by the expression of Phox2b, Ret, and p75 and by explants grown under the kidney capsule or in organ culture., PMID:9758704
For research use only. Not for human or drug use.
