Catalog No.
PHJ79001
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ADAM28 (Lys204-Asn397).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
MDCL, MDC-L, Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L, ADAM 28, ADAM28, eMDC II, ADAM23, Disintegrin and metalloproteinase domain-containing protein 28
Purification
Purified by antigen affinity column.
Accession
Q9UKQ2
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Selective Inhibition of ADAM28 Suppresses Lung Carcinoma Cell Growth and Metastasis., PMID:30190423
Characterization of CD200 Ectodomain Shedding., PMID:27111430
ADAM28 is expressed by epithelial cells in human normal tissues and protects from C1q-induced cell death., PMID:26918856
Src plays a key role in ADAM28 expression in v-src-transformed epithelial cells and human carcinoma cells., PMID:24007880
Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor., PMID:22636800
Modulation of integrin α4β1 by ADAM28 promotes lymphocyte adhesion and transendothelial migration., PMID:21332445
Essential role of ADAM28 in regulating the proliferation and differentiation of human dental papilla mesenchymal cells (hDPMCs)., PMID:18690470
ADAM28 is overexpressed in human breast carcinomas: implications for carcinoma cell proliferation through cleavage of insulin-like growth factor binding protein-3., PMID:17047053
ADAM28 participates in the regulation of tooth development., PMID:16836973
ADAM disintegrin-like domain recognition by the lymphocyte integrins alpha4beta1 and alpha4beta7., PMID:15504110
Integrin alpha4beta1-dependent adhesion to ADAM 28 (MDC-L) requires an extended surface of the disintegrin domain., PMID:12667064
The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1., PMID:11724793