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Anti-Human ADAM28 Polyclonal Antibody

Catalog #:   PHJ79001 Specific References (12) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q9UKQ2
Overview

Catalog No.

PHJ79001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ADAM28 (Lys204-Asn397).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

MDCL, MDC-L, Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L, ADAM 28, ADAM28, eMDC II, ADAM23, Disintegrin and metalloproteinase domain-containing protein 28

Purification

Purified by antigen affinity column.

Accession

Q9UKQ2

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with ADAM28 antibody (PHJ79001) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 25 kDa
    Observed MW: 25 kDa
References

Selective Inhibition of ADAM28 Suppresses Lung Carcinoma Cell Growth and Metastasis., PMID:30190423

Characterization of CD200 Ectodomain Shedding., PMID:27111430

ADAM28 is expressed by epithelial cells in human normal tissues and protects from C1q-induced cell death., PMID:26918856

Src plays a key role in ADAM28 expression in v-src-transformed epithelial cells and human carcinoma cells., PMID:24007880

Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor., PMID:22636800

Modulation of integrin α4β1 by ADAM28 promotes lymphocyte adhesion and transendothelial migration., PMID:21332445

Essential role of ADAM28 in regulating the proliferation and differentiation of human dental papilla mesenchymal cells (hDPMCs)., PMID:18690470

ADAM28 is overexpressed in human breast carcinomas: implications for carcinoma cell proliferation through cleavage of insulin-like growth factor binding protein-3., PMID:17047053

ADAM28 participates in the regulation of tooth development., PMID:16836973

ADAM disintegrin-like domain recognition by the lymphocyte integrins alpha4beta1 and alpha4beta7., PMID:15504110

Integrin alpha4beta1-dependent adhesion to ADAM 28 (MDC-L) requires an extended surface of the disintegrin domain., PMID:12667064

The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1., PMID:11724793

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-Human ADAM28 Polyclonal Antibody [PHJ79001]
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