Catalog No.
PHJ34101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human KLK6 (Gln36-Lys244).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PRSS9, Serine protease 9, Neurosin, Zyme, KLK6, SP59, Kallikrein-6, PRSS18, Serine protease 18, Protease M
Purification
Purified by antigen affinity column.
Accession
Q92876
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Association of neurobiological and immune serum biomarkers with Toxoplasma gondii infection in patients with schizophrenia., PMID:40397143
Role of cathepsin D induced by Porphyromonas gingivalis lipopolysaccharide in periodontitis., PMID:36788303
Inhibition of excessive kallikrein-8 improves neuroplasticity in Alzheimer's disease mouse model., PMID:31734318
Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer., PMID:30114962
Kallikrein 6 secreted by oligodendrocytes regulates the progression of experimental autoimmune encephalomyelitis., PMID:29086442
Study of kallikrein-related peptidase 6 (KLK6) and its complex with α1-antitrypsin in biological fluids., PMID:28672746
Genomic markers of panitumumab resistance including ERBB2/ HER2 in a phase II study of KRAS wild-type (wt) metastatic colorectal cancer (mCRC)., PMID:26980732
Development of Monoclonal Antibodies and Characterization of an ELISA Platform Against Kallikrein-Related Peptidase 6 as a Tumor Biomarker., PMID:26492623
Development of monoclonal antibodies to human kallikrein-related peptidase 6 (KLK6) and their use in an immunofluorometric assay for free KLK6., PMID:25153392
Cancer antigen 125, human epididymis 4, kallikrein 6, osteopontin and soluble mesothelin-related peptide immunocomplexed with immunoglobulin M in epithelial ovarian cancer diagnosis., PMID:24013103
Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6., PMID:23216878
Stromal cell-associated expression of kallikrein-related peptidase 6 (KLK6) indicates poor prognosis of ovarian cancer patients., PMID:22505521
One round of SELEX for the generation of DNA aptamers directed against KLK6., PMID:22505517
Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis., PMID:22335454
Impact of MUC1 mucin downregulation in the phenotypic characteristics of MKN45 gastric carcinoma cell line., PMID:22073229
Kallikrein-related peptidase 6 in Alzheimer's disease and vascular dementia., PMID:20846516
Differential N-glycosylation of kallikrein 6 derived from ovarian cancer cells or the central nervous system., PMID:19088065
Prognostic value of kallikrein-related peptidase 6 protein expression levels in advanced ovarian cancer evaluated by automated quantitative analysis (AQUA)., PMID:18957059
Immunofluorometric activity-based probe analysis of active KLK6 in biological fluids., PMID:18627291
Kallikrein 6 is a mediator of K-RAS-dependent migration of colon carcinoma cells., PMID:18627290
Expression of kallikrein-related peptidases (KRP/hK5, 7, 6, 8) in subtypes of human lung carcinoma., PMID:18182244
Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients., PMID:17518992
Transcriptional upregulation of human tissue kallikrein 6 in ovarian cancer: clinical and mechanistic aspects., PMID:17242704
Characterization of human kallikreins 6 and 10 in ascites fluid from ovarian cancer patients., PMID:16864975
Recombinant kallikrein expression: site-specific integration for hK6 production in human cells., PMID:16800729
Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases., PMID:16086736
Human kallikrein 6 degrades extracellular matrix proteins and may enhance the metastatic potential of tumour cells., PMID:15557757
Characterisation of human kallikrein 6/protease M expression in ovarian cancer., PMID:15305183
The chemopreventive agent alpha-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells., PMID:15057874
[Kallikrein-family serine protease in the central nervous system]., PMID:14531278
Immunohistochemical localization of human kallikreins 6 and 10 in pancreatic islets., PMID:12769263
Purification of human kallikrein 6 from biological fluids and identification of its complex with alpha(1)-antichymotrypsin., PMID:12709365
Human kallikrein 13 expression in normal tissues: an immunohistochemical study., PMID:12642628
Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease., PMID:12480753
Immunofluorometric quantitation and histochemical localisation of kallikrein 6 protein in ovarian cancer tissue: a new independent unfavourable prognostic biomarker., PMID:12232761
Decreased concentration of human kallikrein 6 in brain extracts of Alzheimer's disease patients., PMID:12074831
The spectrum of human kallikrein 6 (zyme/protease M/neurosin) expression in human tissues as assessed by immunohistochemistry., PMID:11668196
Characterization of a brain-related serine protease, neurosin (human kaillikrein 6), in human cerebrospinal fluid., PMID:11388408
Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma., PMID:11124344
Increased expression of protease M in ovarian tumors., PMID:11054022
Immunofluorometric assay of human kallikrein 6 (zyme/protease M/neurosin) and preliminary clinical applications., PMID:11018688
Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's disease and Parkinson's disease., PMID:10997858
A novel protease homolog differentially expressed in breast and ovarian cancer., PMID:8898378