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Anti-Human KLK6 Polyclonal Antibody

Catalog #:   PHJ34101 Specific References (43) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q92876
Overview

Catalog No.

PHJ34101

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KLK6 (Gln36-Lys244).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

PRSS9, Serine protease 9, Neurosin, Zyme, KLK6, SP59, Kallikrein-6, PRSS18, Serine protease 18, Protease M

Purification

Purified by antigen affinity column.

Accession

Q92876

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with KLK6 antibody (PHJ34101) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 35 kDa
    Observed MW: 35 kDa
References

Association of neurobiological and immune serum biomarkers with Toxoplasma gondii infection in patients with schizophrenia., PMID:40397143

Role of cathepsin D induced by Porphyromonas gingivalis lipopolysaccharide in periodontitis., PMID:36788303

Inhibition of excessive kallikrein-8 improves neuroplasticity in Alzheimer's disease mouse model., PMID:31734318

Kallikrein-related peptidases represent attractive therapeutic targets for ovarian cancer., PMID:30114962

Kallikrein 6 secreted by oligodendrocytes regulates the progression of experimental autoimmune encephalomyelitis., PMID:29086442

Study of kallikrein-related peptidase 6 (KLK6) and its complex with α1-antitrypsin in biological fluids., PMID:28672746

Genomic markers of panitumumab resistance including ERBB2/ HER2 in a phase II study of KRAS wild-type (wt) metastatic colorectal cancer (mCRC)., PMID:26980732

Development of Monoclonal Antibodies and Characterization of an ELISA Platform Against Kallikrein-Related Peptidase 6 as a Tumor Biomarker., PMID:26492623

Development of monoclonal antibodies to human kallikrein-related peptidase 6 (KLK6) and their use in an immunofluorometric assay for free KLK6., PMID:25153392

Cancer antigen 125, human epididymis 4, kallikrein 6, osteopontin and soluble mesothelin-related peptide immunocomplexed with immunoglobulin M in epithelial ovarian cancer diagnosis., PMID:24013103

Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6., PMID:23216878

Stromal cell-associated expression of kallikrein-related peptidase 6 (KLK6) indicates poor prognosis of ovarian cancer patients., PMID:22505521

One round of SELEX for the generation of DNA aptamers directed against KLK6., PMID:22505517

Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis., PMID:22335454

Impact of MUC1 mucin downregulation in the phenotypic characteristics of MKN45 gastric carcinoma cell line., PMID:22073229

Kallikrein-related peptidase 6 in Alzheimer's disease and vascular dementia., PMID:20846516

Differential N-glycosylation of kallikrein 6 derived from ovarian cancer cells or the central nervous system., PMID:19088065

Prognostic value of kallikrein-related peptidase 6 protein expression levels in advanced ovarian cancer evaluated by automated quantitative analysis (AQUA)., PMID:18957059

Immunofluorometric activity-based probe analysis of active KLK6 in biological fluids., PMID:18627291

Kallikrein 6 is a mediator of K-RAS-dependent migration of colon carcinoma cells., PMID:18627290

Expression of kallikrein-related peptidases (KRP/hK5, 7, 6, 8) in subtypes of human lung carcinoma., PMID:18182244

Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients., PMID:17518992

Transcriptional upregulation of human tissue kallikrein 6 in ovarian cancer: clinical and mechanistic aspects., PMID:17242704

Characterization of human kallikreins 6 and 10 in ascites fluid from ovarian cancer patients., PMID:16864975

Recombinant kallikrein expression: site-specific integration for hK6 production in human cells., PMID:16800729

Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases., PMID:16086736

Human kallikrein 6 degrades extracellular matrix proteins and may enhance the metastatic potential of tumour cells., PMID:15557757

Characterisation of human kallikrein 6/protease M expression in ovarian cancer., PMID:15305183

The chemopreventive agent alpha-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells., PMID:15057874

[Kallikrein-family serine protease in the central nervous system]., PMID:14531278

Immunohistochemical localization of human kallikreins 6 and 10 in pancreatic islets., PMID:12769263

Purification of human kallikrein 6 from biological fluids and identification of its complex with alpha(1)-antichymotrypsin., PMID:12709365

Human kallikrein 13 expression in normal tissues: an immunohistochemical study., PMID:12642628

Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease., PMID:12480753

Immunofluorometric quantitation and histochemical localisation of kallikrein 6 protein in ovarian cancer tissue: a new independent unfavourable prognostic biomarker., PMID:12232761

Decreased concentration of human kallikrein 6 in brain extracts of Alzheimer's disease patients., PMID:12074831

The spectrum of human kallikrein 6 (zyme/protease M/neurosin) expression in human tissues as assessed by immunohistochemistry., PMID:11668196

Characterization of a brain-related serine protease, neurosin (human kaillikrein 6), in human cerebrospinal fluid., PMID:11388408

Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma., PMID:11124344

Increased expression of protease M in ovarian tumors., PMID:11054022

Immunofluorometric assay of human kallikrein 6 (zyme/protease M/neurosin) and preliminary clinical applications., PMID:11018688

Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's disease and Parkinson's disease., PMID:10997858

A novel protease homolog differentially expressed in breast and ovarian cancer., PMID:8898378

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human KLK6 Polyclonal Antibody [PHJ34101]
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