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Anti-Human CD11d/ITGAD Polyclonal Antibody

Catalog #:   PHG49401 Specific References (82) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q13349
Overview

Catalog No.

PHG49401

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD11d/ITGAD (Ala978-Asn1099).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Leukointegrin alpha D, Integrin alpha-D, CD11d, CD11 antigen-like family member D, ITGAD, ADB2

Purification

Purified by antigen affinity column.

Accession

Q13349

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CD11d/ITGAD antibody (PHG49401) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 16 kDa
    Observed MW: 16 kDa
References

Humanized anti-CD11d monoclonal antibodies suitable for basic research and therapeutic applications., PMID:39839909

Humanized anti-CD11d monoclonal antibodies suitable for basic research and therapeutic applications., PMID:39839909

CD11d is a novel antigen on chicken leukocytes., PMID:32534212

CD11d is a novel antigen on chicken leukocytes., PMID:32534212

Characterisation of a New Human Alveolar Macrophage-Like Cell Line (Daisy)., PMID:31732808

Characterisation of a New Human Alveolar Macrophage-Like Cell Line (Daisy)., PMID:31732808

The effectiveness of the anti-CD11d treatment is reduced in rat models of spinal cord injury that produce significant levels of intraspinal hemorrhage., PMID:28587875

The effectiveness of the anti-CD11d treatment is reduced in rat models of spinal cord injury that produce significant levels of intraspinal hemorrhage., PMID:28587875

The Role of Integrins αMβ2 (Mac-1, CD11b/CD18) and αDβ2 (CD11d/CD18) in Macrophage Fusion., PMID:27315778

The Role of Integrins αMβ2 (Mac-1, CD11b/CD18) and αDβ2 (CD11d/CD18) in Macrophage Fusion., PMID:27315778

CD11d integrin blockade reduces the systemic inflammatory response syndrome after traumatic brain injury in rats., PMID:26169930

CD11d integrin blockade reduces the systemic inflammatory response syndrome after traumatic brain injury in rats., PMID:26169930

Immunohistochemical evaluation of the effects of paraffin section storage on biomarker stability., PMID:23435571

Immunohistochemical evaluation of the effects of paraffin section storage on biomarker stability., PMID:23435571

Treatment with an anti-CD11d integrin antibody reduces neuroinflammation and improves outcome in a rat model of repeated concussion., PMID:23414334

Treatment with an anti-CD11d integrin antibody reduces neuroinflammation and improves outcome in a rat model of repeated concussion., PMID:23414334

Hepatosplenic and hepatocytotropic T-cell lymphoma: two distinct types of T-cell lymphoma in dogs., PMID:22711745

Hepatosplenic and hepatocytotropic T-cell lymphoma: two distinct types of T-cell lymphoma in dogs., PMID:22711745

A CD11d monoclonal antibody treatment reduces tissue injury and improves neurological outcome after fluid percussion brain injury in rats., PMID:22676851

A CD11d monoclonal antibody treatment reduces tissue injury and improves neurological outcome after fluid percussion brain injury in rats., PMID:22676851

The systemic inflammatory response after spinal cord injury in the rat is decreased by α4β1 integrin blockade., PMID:22150233

The systemic inflammatory response after spinal cord injury in the rat is decreased by α4β1 integrin blockade., PMID:22150233

Anti-CD11d monoclonal antibody treatment for rat spinal cord compression injury., PMID:22078757

Anti-CD11d monoclonal antibody treatment for rat spinal cord compression injury., PMID:22078757

CD11d Antibody Treatment Improves Recovery in Spinal Cord-Injured Mice., PMID:22044160

CD11d Antibody Treatment Improves Recovery in Spinal Cord-Injured Mice., PMID:22044160

Characterization of immune cell infiltration into canine intracranial meningiomas., PMID:21987303

Characterization of immune cell infiltration into canine intracranial meningiomas., PMID:21987303

CD11d integrin blockade reduces the systemic inflammatory response syndrome after spinal cord injury., PMID:21784069

CD11d integrin blockade reduces the systemic inflammatory response syndrome after spinal cord injury., PMID:21784069

Anti-CD11d monoclonal antibody treatment for rat spinal cord compression injury., PMID:21145887

Anti-CD11d monoclonal antibody treatment for rat spinal cord compression injury., PMID:21145887

A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury., PMID:20146558

A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury., PMID:20146558

A systematic review of directly applied biologic therapies for acute spinal cord injury., PMID:20082560

A systematic review of directly applied biologic therapies for acute spinal cord injury., PMID:20082560

Mary Allen Engle Award: The glue of life--a career retrospective., PMID:21686217

Mary Allen Engle Award: The glue of life--a career retrospective., PMID:21686217

Gene expression profiling in anti-CD11d mAb-treated spinal cord-injured rats., PMID:19250688

Gene expression profiling in anti-CD11d mAb-treated spinal cord-injured rats., PMID:19250688

The role of integrin alpha D beta2 (CD11d/CD18) in monocyte/macrophage migration., PMID:18621369

The role of integrin alpha D beta2 (CD11d/CD18) in monocyte/macrophage migration., PMID:18621369

Transient blockage of the CD11d/CD18 integrin reduces contusion volume and macrophage infiltration after traumatic brain injury in rats., PMID:18374312

Transient blockage of the CD11d/CD18 integrin reduces contusion volume and macrophage infiltration after traumatic brain injury in rats., PMID:18374312

Comparison of two polymer-based immunohistochemical detection systems: ENVISION+ and ImmPRESS., PMID:17204059

Comparison of two polymer-based immunohistochemical detection systems: ENVISION+ and ImmPRESS., PMID:17204059

An established feline monocytic cell line., PMID:17058791

An established feline monocytic cell line., PMID:17058791

A therapeutic time window for anti-CD 11d monoclonal antibody treatment yielding reduced secondary tissue damage and enhanced behavioral recovery following severe spinal cord injury., PMID:17048772

A therapeutic time window for anti-CD 11d monoclonal antibody treatment yielding reduced secondary tissue damage and enhanced behavioral recovery following severe spinal cord injury., PMID:17048772

Methylprednisolone causes minimal improvement after spinal cord injury in rats, contrasting with benefits of an anti-integrin treatment., PMID:16379576

Methylprednisolone causes minimal improvement after spinal cord injury in rats, contrasting with benefits of an anti-integrin treatment., PMID:16379576

Autonomic dysreflexia after spinal cord injury: central mechanisms and strategies for prevention., PMID:16198705

Autonomic dysreflexia after spinal cord injury: central mechanisms and strategies for prevention., PMID:16198705

Anti-CD11d antibody treatment reduces free radical formation and cell death in the injured spinal cord of rats., PMID:15992367

Anti-CD11d antibody treatment reduces free radical formation and cell death in the injured spinal cord of rats., PMID:15992367

Comparison of effects of methylprednisolone and anti-CD11d antibody treatments on autonomic dysreflexia after spinal cord injury., PMID:15890340

Comparison of effects of methylprednisolone and anti-CD11d antibody treatments on autonomic dysreflexia after spinal cord injury., PMID:15890340

Anti-CD11d integrin antibody treatment restores normal serotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord., PMID:15659600

Anti-CD11d integrin antibody treatment restores normal serotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord., PMID:15659600

A monoclonal antibody to CD11d reduces the inflammatory infiltrate into the injured spinal cord: a potential neuroprotective treatment., PMID:15465595

A monoclonal antibody to CD11d reduces the inflammatory infiltrate into the injured spinal cord: a potential neuroprotective treatment., PMID:15465595

An anti-CD11d integrin antibody reduces cyclooxygenase-2 expression and protein and DNA oxidation after spinal cord injury in rats., PMID:15312174

An anti-CD11d integrin antibody reduces cyclooxygenase-2 expression and protein and DNA oxidation after spinal cord injury in rats., PMID:15312174

Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function., PMID:15102919

Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function., PMID:15102919

Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats., PMID:15009633

Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats., PMID:15009633

Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: a potential new anti-inflammatory treatment., PMID:11031083

Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: a potential new anti-inflammatory treatment., PMID:11031083

Neutrophil transmigration across human airway epithelial monolayers: mechanisms and dependence on electrical resistance., PMID:10970831

Neutrophil transmigration across human airway epithelial monolayers: mechanisms and dependence on electrical resistance., PMID:10970831

Characterization of the diffuse mucosal associated lymphoid tissue of feline small intestine., PMID:10889297

Characterization of the diffuse mucosal associated lymphoid tissue of feline small intestine., PMID:10889297

The leukocyte integrin alpha D beta 2 binds VCAM-1: evidence for a binding interface between I domain and VCAM-1., PMID:10438935

The leukocyte integrin alpha D beta 2 binds VCAM-1: evidence for a binding interface between I domain and VCAM-1., PMID:10438935

alphadbeta2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM-1)., PMID:9841932

alphadbeta2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM-1)., PMID:9841932

The leukointegrin alpha d/beta 2 (alpha d/CD18): specific changes in surface expression in patients on hemodialysis., PMID:9759518

The leukointegrin alpha d/beta 2 (alpha d/CD18): specific changes in surface expression in patients on hemodialysis., PMID:9759518

Requirements for alpha d in IgG immune complex-induced rat lung injury., PMID:9551942

Requirements for alpha d in IgG immune complex-induced rat lung injury., PMID:9551942

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human CD11d/ITGAD Polyclonal Antibody [PHG49401]
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