Catalog No.
PHF68201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human NKX6-1 (Thr242-Glu320).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A, NKX6A, NKX6-1
Purification
Purified by antigen affinity column.
Accession
P78426
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Preconditioning of human umbilical cord mesenchymal stem cells with deferoxamine potentiates the capacity of the secretome released from the cells and promotes immunomodulation and beta cell regeneration in a rat model of type 1 diabetes., PMID:38340421
Nanoparticle-mediated CRISPR/dCas9a activation of multiple transcription factors to engineer insulin-producing cells., PMID:36789698
Oligodendroglia Generated From Adult Rat Adipose Tissue by Direct Cell Conversion., PMID:35223826
A simple method for the generation of insulin producing cells from bone marrow mesenchymal stem cells., PMID:31111346
Nitrate induces a type 1 diabetic profile in alligator hatchlings., PMID:28942280
Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors., PMID:28835709
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development., PMID:28196600
Development of Islet Organoids from H9 Human Embryonic Stem Cells in Biomimetic 3D Scaffolds., PMID:27960594
Postnatal maturation of mouse medullo-spinal cerebrospinal fluid-contacting neurons., PMID:27939302
Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development., PMID:25576928
Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet., PMID:23884882
Role of BMP signaling in pancreatic progenitor differentiation from human embryonic stem cells., PMID:23468018
The SDF-1α/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells., PMID:22761699
Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation., PMID:22509401
Induction and selection of Sox17-expressing endoderm cells generated from murine embryonic stem cells., PMID:22123608
Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance., PMID:21964593
Pancreatic islet and progenitor cell surface markers with cell sorting potential., PMID:21947380
Lectin-based isolation and culture of mouse embryonic motoneurons., PMID:21946816
Streptozotocin-induced expression of Ngn3 and Pax4 in neonatal rat pancreatic α-cells., PMID:21734788
Neuronal restrictive silencing factor silencing induces human amniotic fluid-derived stem cells differentiation into insulin-producing cells., PMID:20942606
Human bone marrow mesenchymal stem cells differentiate into insulin-producing cells upon microenvironmental manipulation in vitro., PMID:19505629
Mesenchymal stem cells derived from human exocrine pancreas express transcription factors implicated in beta-cell development., PMID:18580448
Generation and characterization of Ptf1a antiserum and localization of Ptf1a in relation to Nkx6.1 and Pdx1 during the earliest stages of mouse pancreas development., PMID:18347078
Specificity of four monoclonal anti-NKx6-1 antibodies., PMID:18212389
Pancreatic endocrine and exocrine cell ontogeny from renal capsule transplanted embryonic stem cells in streptozocin-injured mice., PMID:17875656
Isolation, tissue localization, and cellular characterization of progenitors derived from adult human salivary glands., PMID:17579552
Generation of insulin-secreting cells from human embryonic stem cells., PMID:16759282
Generation and characterization of monoclonal antibodies against the transcription factor Nkx6.1., PMID:16401696
Genomic organization and embryonic expression of Igsf8, an immunoglobulin superfamily member implicated in development of the nervous system and organ epithelia., PMID:12595239
Molecular mapping of the origin of postnatal spinal cord ependymal cells: evidence that adult ependymal cells are derived from Nkx6.1+ ventral neural progenitor cells., PMID:12528188
Characterization of beta cells developed in vitro from rat embryonic pancreatic epithelium., PMID:10030591
For research use only. Not for human or drug use.
