Catalog No.
PHE22901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD103/ITGAE (Val37-Asn140).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Mucosal lymphocyte 1 antigen, Integrin alpha-E, Integrin alpha-IEL, HML-1 antigen, CD103, ITGAE
Purification
Purified by antigen affinity column.
Accession
P38570
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Expanded adaptive NKG2C+ NK cells exhibit potent ADCC and functional responses against HBV-infected hepatoma cell lines., PMID:40501566
Harnessing local and system immune profiling delineating differential responders to first-line sintilimab (anti-PD-1 antibody) combined with chemotherapy in extensive-stage small cell lung cancer: an exploratory biomarker analysis of a phase II study., PMID:40404633
Conversion Surgery Performed Following Durvalumab Combined With Gemcitabine and Cisplatin in Cholangiocarcinoma: A Case Report., PMID:40294984
Identification and characterization of tissue resident memory T cells in malignant pleural effusions associated with non-small cell lung cancer., PMID:40285480
KLF2 inhibition expands tumor-resident T cells and enhances tumor immunity., PMID:40162209
IL-6 underlies microenvironment immunosuppression and resistance to therapy in glioblastoma., PMID:40161763
Enhancing Immune Responses Through Modulation of Innate Cell Microenvironments in Lymph Nodes with Virus-Mimetic Vaccines., PMID:40072248
MIP-3α-antigen fusion DNA vaccine enhances sex differences in tuberculosis model and alters dendritic cell activity early post vaccination., PMID:39877094
Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression., PMID:39838375
Characterization of Dendritic Cells and Myeloid-Derived Suppressor Cells Expressing Major Histocompatibility Complex Class II in Secondary Lymphoid Organs in Systemic Lupus Erythematosus-Prone Mice., PMID:39769367
Polyphenol oxidase cross-linking enhances whey protein-induced systemic food allergy by regulating miRNA in CD4+ T cells., PMID:39744957
Vaccines targeting p53 mutants elicit anti-tumor immunity., PMID:39740750
Enhancing Tumor Immunity with IL-12 and PD-1 Blockade: A Strategy for Inducing Robust Central Memory T Cell Responses in Resistant Cancer Model., PMID:39584994
Hairy cell leukemia (HCL) and HCL-like disorders: present, emergent treatment options and future directions., PMID:39535173
Fecal microbiota transplantation alleviates food allergy in neonatal mice via the PD-1/PD-L1 pathway and change of the microbiota composition., PMID:39403173
Fecal microbiota transplantation as a new way for OVA-induced atopic dermatitis of juvenile mice., PMID:39298815
Phenotypic profiling of human induced regulatory T cells at early differentiation: insights into distinct immunosuppressive potential., PMID:39264416
Helicobacter pylori Infection Affects the Tumor Immune Microenvironment of Esophageal Cancer Patients., PMID:39197894
Pembrolizumab and Cabozantinib in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Long-term Survival Update with a Biomarker Analysis., PMID:39167623
Clara cell 10 (CC10) protein attenuates allergic airway inflammation by modulating lung dendritic cell functions., PMID:39078462
Secukinumab and Dead Sea Climatotherapy Impact Resolved Psoriasis Skin Differently Potentially Affecting Disease Memory., PMID:38892277
MHC-II presentation by oral Langerhans cells impacts intraepithelial Tc17 abundance and Candida albicans oral infection via CD4 T cells., PMID:38872986
Protective function and differentiation cues of brain-resident CD8+ T cells during surveillance of latent Toxoplasma gondii infection., PMID:38838017
Sex-biased immunogenicity of a mucosal subunit vaccine against SARS-CoV-2 in mice., PMID:38835757
CD8+ tissue-resident memory T cells are expanded in primary Sjögren's disease and can be therapeutically targeted by CD103 blockade., PMID:38777379
MAdCAM-1 co-stimulation combined with retinoic acid and TGF-β induces blood CD8+ T cells to adopt a gut CD101+ TRM phenotype., PMID:38729611
Stage-dependent immunity orchestrates AQP4 antibody-guided NMOSD pathology: a role for netting neutrophils with resident memory T cells in situ., PMID:38658413
Blockade of neutrophil extracellular trap components ameliorates cholestatic liver disease in Mdr2 (Abcb4) knockout mice., PMID:38653165
Down-regulated HHLA2 enhances neoadjuvant immunotherapy efficacy in patients with non-small cell lung cancer (NSCLC) with chronic obstructive pulmonary disease (COPD)., PMID:38553708
Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses., PMID:38550714
Migratory CD103+CD11b+ cDC2s in Peyer's patches are critical for gut IgA responses following oral immunization., PMID:38492746
Engineered lactococcus lactis intrapleural therapy promotes regression of malignant pleural effusion by enhancing antitumor immunity., PMID:38432582
Activin A levels are raised during human tuberculosis and blockade of the activin signaling axis influences murine responses to M. tuberculosis infection., PMID:38376260
[Establishment of a 21-color Panel for the Detection of Immune Cell Subsets
in Human Non-small Cell Lung Cancer Tumor Tissues with Flow Cytometry]., PMID:38296626
NK cell-triggered CCL5/IFNγ-CXCL9/10 axis underlies the clinical efficacy of neoadjuvant anti-HER2 antibodies in breast cancer., PMID:38167224
Regulatory role of RGMb in lung injury promoted by the combination of carbon ion irradiation and anti-PD-1 antibody through Erk1/2 and p38 MAPK pathways., PMID:38042034
Alcaligenes lipid A functions as a superior mucosal adjuvant to monophosphoryl lipid A via the recruitment and activation of CD11b+ dendritic cells in nasal tissue., PMID:38006376
Development of [89Zr]Zr-hCD103.Fab01A and [68Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET., PMID:37985555
Usefulness of Biopsy Specimens for Evaluating CD103+ Tumor-resident Memory T Cells in Esophageal Cancer., PMID:37909993
Significance of CD103+ tissue-resident memory T cells for predicting the effectiveness of immune checkpoint inhibitors in esophageal cancer., PMID:37864146
The effect of Toll-like receptor agonists on the immunogenicity of MVA-SARS-2-S vaccine after intranasal administration in mice., PMID:37854858
Evaluation of Diagnostic Usefulness of CD200 Expression in B-cell Chronic Lymphoproliferative Disorders., PMID:37786819
Optimising multiplex immunofluorescence staining for characterising the tumour immune micro-environment., PMID:37741563
Prognostic Impact of Tumor-Infiltrating Lymphocytes, Tertiary Lymphoid Structures, and Neutrophil-to-Lymphocyte Ratio in Pulmonary Metastases from Uterine Leiomyosarcoma., PMID:37658268
Proinflammatory allogeneic dendritic cells enhance the therapeutic efficacy of systemic anti-4-1BB treatment., PMID:37654492
Prognostic benefit of TILs independent of clinicopathological and molecular factors., PMID:37443345
Skin Whole-Mount Immunofluorescent Staining Protocol, 3D Visualization, and Spatial Image Analysis., PMID:37338194
Biological and molecular studies on specific immune cells treated with checkpoint inhibitors for the thera-personal approach of breast cancer patients (ex-vivo study)., PMID:37305162
IgA2 immune complexes selectively promote inflammation by human CD103+ dendritic cells., PMID:37006318
The Underappreciated Role of Secretory IgA in IBD., PMID:36943800
For research use only. Not for human or drug use.
