Catalog No.
PHD85501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MARCKS (Lys155-Gly199).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Myristoylated alanine-rich C-kinase substrate, 80K-L protein, PKCSL, Protein kinase C substrate, 80 kDa protein, light chain, PRKCSL, MACS, MARCKS
Purification
Purified by antigen affinity column.
Accession
P29966
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Activation of Marck-like Genes and Proteins During Initial Phases of Regeneration in the Amputated Tail and Limb of the Lizard Podarcis muralis., PMID:40265370
Small Organic Compounds Mimicking the Effector Domain of Myristoylated Alanine-Rich C-Kinase Substrate Stimulate Female-Specific Neurite Outgrowth., PMID:37762575
MARCKS Effector Domain, a reversible lipid ligand, illuminates late stages of membrane fusion., PMID:37672336
Targeting carcinoma-associated mesothelial cells with antibody-drug conjugates in ovarian carcinomatosis., PMID:37555348
Analysis of phagocytosis by mIgM+ lymphocytes depending on monoclonal antibodies against IgM of largemouth bass (Micropterus salmoides)., PMID:35314332
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice., PMID:35101976
D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain., PMID:34556581
A plasma-derived extracellular vesicle mRNA classifier for the detection of breast cancer., PMID:34268084
Intracellular amyloid hypothesis for ultra-early phase pathology of Alzheimer's disease., PMID:33876503
Single-cell RNA sequencing reveals that lung mesenchymal progenitor cells in IPF exhibit pathological features early in their differentiation trajectory., PMID:32636398
Interaction between Polysialic Acid and the MARCKS-ED Peptide at the Molecular Level., PMID:32412743
Novel Treatment Targets Based on Insights in the Etiology of Depression: Role of IL-6 Trans-Signaling and Stress-Induced Elevation of Glutamate and ATP., PMID:31362361
MARCKS regulates tonic and chronic active B cell receptor signaling., PMID:30209404
Mechanism of inhibition of taurolithocholate-induced retrieval of plasma membrane MRP2 by cyclic AMP and tauroursodeoxycholate., PMID:29192063
Generation and intracellular trafficking of a polysialic acid-carrying fragment of the neural cell adhesion molecule NCAM to the cell nucleus., PMID:28819302
Targeting mast cells: Uncovering prolific therapeutic role in myriad diseases., PMID:27694038
HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease., PMID:27557632
Vinorelbine and epirubicin share common features with polysialic acid and modulate neuronal and glial functions., PMID:26443186
Activation of lymphotoxin-beta receptor enhances the LPS-induced expression of IL-8 through NF-κB and IRF-1., PMID:25887375
Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy., PMID:25226551
Myristoylated Alanine Rich C Kinase Substrate (MARCKS) is essential to β2-integrin dependent responses of equine neutrophils., PMID:24857637
Structural characterization of a neuroblast-specific phosphorylated region of MARCKS., PMID:24590112
Endothelial cell adhesion to soluble vascular endothelial growth factor receptor-1 triggers a cell dynamic and angiogenic phenotype., PMID:24174428
MARCKS protein is phosphorylated and regulates calcium mobilization during human acrosomal exocytosis., PMID:23704996
MARCKS protein mediates hydrogen peroxide regulation of endothelial permeability., PMID:22927426
Directed migration of mouse macrophages in vitro involves myristoylated alanine-rich C-kinase substrate (MARCKS) protein., PMID:22623357
MARCKS actin-binding capacity mediates actin filament assembly during mitosis in human hepatic stellate cells., PMID:22555845
Serum antibodies against frameshift peptides in microsatellite unstable colorectal cancer patients with Lynch syndrome., PMID:19957108
Electroconvulsive seizure increases phosphorylation of PKC substrates, including GAP-43, MARCKS, and neurogranin, in rat brain., PMID:19837121
Mutation of the protein kinase C site in borna disease virus phosphoprotein abrogates viral interference with neuronal signaling and restores normal synaptic activity., PMID:19424436
Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells., PMID:19252893
Prediction of the immunogenic potential of frameshift-mutated antigens in microsatellite instable cancer., PMID:18506693
Investigation into the mechanism regulating MRP localization., PMID:17897642
Borna disease virus blocks potentiation of presynaptic activity through inhibition of protein kinase C signaling., PMID:16552443
Involvement of Rho-kinase in inflammatory and neuropathic pain through phosphorylation of myristoylated alanine-rich C-kinase substrate (MARCKS)., PMID:15708490
The involvement of protein kinase C and actin filaments in cortical granule exocytosis in the rat., PMID:15695610
Identification of myristoylated alanine-rich C kinase substrate (MARCKS) in astrocytes., PMID:15574358
Identification of the chicken MARCKS phosphorylation site specific for differentiating neurons as Ser 25 using a monoclonal antibody and mass spectrometry., PMID:14998167
Immunoseparation of Prion protein-enriched domains from other detergent-resistant membrane fractions, isolated from neuronal cells., PMID:14741357
[Probing of the target molecules of Rho-kinase and its function in neuronal cells]., PMID:14727513
Myoblast migration is prevented by a calpain-dependent accumulation of MARCKS., PMID:14720464
Protein phosphorylation in neutrophils monitored with phosphospecific antibodies., PMID:14580883
2-pyrrolidinone induces a long-lasting facilitation of hippocampal synaptic transmission by enhancing alpha7 ACh receptor responses via a PKC pathway., PMID:14499485
Expression of MARCKS mRNA in lateral geniculate nucleus and visual cortex of normal and monocularly deprived macaque monkeys., PMID:12507329
The novel and specific Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine as a probing molecule for Rho-kinase-involved pathway., PMID:12191614
Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor., PMID:12067241
Sustained phosphorylation of MARCKS in differentiating neurogenic regions during chick embryo development., PMID:11675128
Microglial signaling by amyloid beta protein through mitogen-activated protein kinase mediating phosphorylation of MARCKS., PMID:11496150
Apical accumulation of MARCKS in neural plate cells during neurulation in the chick embryo., PMID:11329360
Rho-associated kinase phosphorylates MARCKS in human neuronal cells., PMID:11162562
For research use only. Not for human or drug use.
