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Anti-Human KCNA4 Polyclonal Antibody

Catalog #:   PHD52001 Specific References (18) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P22459
Overview

Catalog No.

PHD52001

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KCNA4 (Glu176-Gly274).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Voltage-gated potassium channel HBK4, Voltage-gated potassium channel HK1, HPCN2, Voltage-gated K(+) channel HuKII, Potassium voltage-gated channel subfamily A member 4, KCNA4L, KCNA4, Voltage-gated potassium channel subunit Kv1.4

Purification

Purified by antigen affinity column.

Accession

P22459

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with KCNA4 antibody (PHD52001) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 24 kDa
    Observed MW: 24 kDa
References

[A case of sporadic late-onset nemaline myopathy associated with myasthenia gravis positive for anti-titin antibody and anti-Kv1.4 antibody]., PMID:32536668

Myasthenia gravis., PMID:31048702

ADAM23 is a negative regulator of Kv1.1/Kv1.4 potassium currents., PMID:30965109

Serological and experimental studies in different forms of myasthenia gravis., PMID:29377162

[Two Cases of Invasive Thymoma with Taste Disorder]., PMID:28174404

[A case of myasthenia gravis with invasive thymoma associated with diffuse panbronchiolitis, alopecia, dysgeusia, cholangitis and myositis]., PMID:25283823

Neuronal transmission stimulates the phosphorylation of Kv1.4 channel at Ser229 through protein kinase A1., PMID:16000151

Heteromultimeric Kv1 channels contribute to myogenic control of arterial diameter., PMID:15618540

K(V)alpha1 channels in murine arterioles: differential cellular expression and regulation of diameter., PMID:11514271

Immunohistochemical study on the distribution of six members of the Kv1 channel subunits in the rat cerebellum., PMID:11259775

Subcellular compartmentalization of a potassium channel (Kv1.4): preferential distribution in dendrites and dendritic spines of neurons in the dorsal cochlear nucleus., PMID:11122345

Voltage-gated K(+)Channel, Kv4.2, localizes predominantly to the transverse-axial tubular system of the rat myocyte., PMID:10860776

Heterogeneous expression of voltage-gated potassium channels of the shaker family (Kv1) in oligodendrocyte progenitors., PMID:10528121

Subunit composition of Kv1 channels in human CNS., PMID:10428084

Regulation of Kv4.2 and Kv1.4 K+ channel expression by myocardial hypertrophic factors in cultured newborn rat ventricular cells., PMID:9710812

Association and colocalization of the Kvbeta1 and Kvbeta2 beta-subunits with Kv1 alpha-subunits in mammalian brain K+ channel complexes., PMID:9334400

Altered K+ channel subunit composition following hormone induction of Kv1.5 gene expression., PMID:8916900

Generation and characterization of subtype-specific monoclonal antibodies to K+ channel alpha- and beta-subunit polypeptides., PMID:8938716

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-Human KCNA4 Polyclonal Antibody [PHD52001]
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