Catalog No.
PHD31201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ATF6 (Ser548-Asp622).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ATF6-alpha, Cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha, ATF6, Activating transcription factor 6 alpha
Purification
Purified by antigen affinity column.
Accession
P18850
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
IL-33 facilitates endoplasmic reticulum stress and pyroptosis in LPS-stimulated ARDS model in vitro., PMID:40118005
Unfolded protein responses in T cell immunity., PMID:39845962
Tocilizumab unfolds colo-protective and immunomodulatory effect in experimentally induced ulcerative colitis via mitigating autophagy and ER stress signaling., PMID:39134818
RNASeq highlights ATF6 pathway regulators for CHO cell engineering with different impacts of ATF6β and WFS1 knockdown on fed-batch production of IgG1., PMID:38898154
Endoplasmic Reticulum Stress and Unfolded Protein Response in Vernal Keratoconjunctivitis., PMID:38597723
APOE and Alzheimer's disease: Pathologic clues from transgenic Drosophila melanogaster., PMID:38537387
Long noncoding RNA XIST: a novel independent prognostic biomarker for patients with ABC-DLBCL receiving R-CHOP treatment., PMID:38426786
Activation of Notch-1 signaling pathway in macrophages to secrete PD-L1 and regulate cytotoxicity of CAR-T cells in diffuse large B-cell lymphoma., PMID:38261741
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway., PMID:36738354
Cell Cycle Analysis of ER Stress and Autophagy., PMID:36087266
Endoplasmic reticulum-stress and unfolded protein response-activation in immune-mediated necrotizing myopathy., PMID:35703068
STIM1-Orai1 Interaction Exacerbates LPS-Induced Inflammation and Endoplasmic Reticulum Stress in Bovine Hepatocytes through Store-Operated Calcium Entry., PMID:35627260
Modulation of the Physical Properties of 3D Spheroids Derived from Human Scleral Stroma Fibroblasts (HSSFs) with Different Axial Lengths Obtained from Surgical Patients., PMID:34698138
The unfolded protein response and apoptotic regulation in the human placenta due to maternal cigarette smoking and pre-eclampsia., PMID:34492309
The special unfolded protein response in plasma cells., PMID:34368957
Carfilzomib Promotes the Unfolded Protein Response and Apoptosis in Cetuximab-Resistant Colorectal Cancer., PMID:34281166
Activation of TREM-1 induces endoplasmic reticulum stress through IRE-1α/XBP-1s pathway in murine macrophages., PMID:33957479
Investigation of the effect of hyperthyroidism on endoplasmic reticulum stress and tran- sient receptor potential canonical 1 channel in the kidney., PMID:33754657
MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells., PMID:33318509
Impact of Bevacizumab on Liver Damage After Massive Hepatectomy in Rats., PMID:31471394
Endoplasmic Reticulum Stress Markers and Their Possible Implications in Leprosy's Pathogenesis., PMID:30647798
Site-1 protease function is essential for the generation of antibody secreting cells and reprogramming for secretory activity., PMID:30254311
New Hope for Pancreatic Ductal Adenocarcinoma Treatment Targeting Endoplasmic Reticulum Stress Response: A Systematic Review., PMID:30134550
The Effect of Culture Temperature on the Aggregation of Recombinant TNFR-Fc is Regulated by the PERK-eIF2a Pathway in CHO Cells., PMID:29848262
Inhibition of GRP78 abrogates radioresistance in oropharyngeal carcinoma cells after EGFR inhibition by cetuximab., PMID:29232380
Activation of unfolded protein response pathway is important for valproic acid mediated increase in immunoglobulin G productivity in recombinant Chinese hamster ovary cells., PMID:28601608
Hepatocellular carcinoma and CXCR3 chemokines: a narrative review., PMID:28240761
Molecular signal networks and regulating mechanisms of the unfolded protein response., PMID:28070992
The Effect of Chronic Ozone Exposure on the Activation of Endoplasmic Reticulum Stress and Apoptosis in Rat Hippocampus., PMID:27826237
Astragalus polysaccharide modulates ER stress response in an OVA-LPS induced murine model of severe asthma., PMID:27645929
Intermedin1-53 Protects Against Myocardial Fibrosis by Inhibiting Endoplasmic Reticulum Stress and Inflammation Induced by Homocysteine in Apolipoprotein E-Deficient Mice., PMID:27052784
Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells., PMID:27464732
The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells., PMID:27119724
Expression and function of HSP110 family in mouse testis after vasectomy., PMID:26952955
Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response., PMID:26779600
Reduced expression of ERp46 under diabetic conditions in β-cells and the effect of liraglutide., PMID:26683792
ER stress-inducible protein MANF selectively expresses in human spleen., PMID:26429332
Interferon-gamma inducible protein 10 (IP10) induced cisplatin resistance of HCC after liver transplantation through ER stress signaling pathway., PMID:26336986
Correlation of ER stress and retinal degeneration in tubby mice., PMID:26325328
Mutation of ATF6 causes autosomal recessive achromatopsia., PMID:26063662
Anti-dsDNA antibodies induce inflammation via endoplasmic reticulum stress in human mesangial cells., PMID:26040555
Advanced glycation end products upregulate the endoplasmic reticulum stress in human periodontal ligament cells., PMID:25415248
Unfolded protein response activation in cataracts., PMID:25263040
Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein response., PMID:25238757
Deficiency of IRE1 and PERK signal pathways in systemic lupus erythematosus., PMID:25226532
Berberine induces hERG channel deficiency through trafficking inhibition., PMID:25171176
Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain., PMID:25157167
ATF6 and caspase 12 expression in Purkinje neurons in acute slices from adult, ethanol-fed rats., PMID:24976582
Ox-LDL induces endothelial cell apoptosis via the LOX-1-dependent endoplasmic reticulum stress pathway., PMID:24911634
A rare variant in human fibroblast activation protein associated with ER stress, loss of enzymatic function and loss of cell surface localisation., PMID:24717288
For research use only. Not for human or drug use.
