Catalog No.
PHD27601
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human TCP1/CCTA (Met1-Asp556).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CCT1, T-complex protein 1 subunit alpha, TCP-1-alpha, CCTA, CCT-alpha, TCP1
Purification
Purified by antigen affinity column.
Accession
P17987
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Integrative analysis of serum proteomics and transcriptomics in hepatitis C., PMID:40082995
Anti-TCP1 Antibody Is a Potential Biomarker for Diagnosing Systemic Lupus Erythematosus., PMID:39201300
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity., PMID:38869076
Multiple-Pathway Synergy Alters Steroidogenesis and Spermatogenesis in Response to an Immunocastration Vaccine in Goat., PMID:38201210
Chaperonin containing TCP-1 (CCT/TRiC) is a novel therapeutic and diagnostic target for neuroblastoma., PMID:36185250
Per a 5-derived T-cell peptides modulate NF-kB signalling to ameliorate allergic inflammation systemically in murine model of cockroach allergic hyper-reactivity., PMID:35443057
Chaperonin containing TCP1 subunit 5 is a tumor associated antigen of non-small cell lung cancer., PMID:28969060
Autoantibodies against protein disulfide isomerase ER-60 are a diagnostic marker for low-grade testicular inflammation., PMID:25205753
Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae., PMID:21672535
Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein., PMID:21093005
Proteomic identification and comparative analysis of asymmetrically arginine-methylated proteins in immortalized, young and senescent cells., PMID:21080485
Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila., PMID:20122915
Subunits of the chaperonin CCT interact with F-actin and influence cell shape and cytoskeletal assembly., PMID:19913534
Searching for new clues about the molecular cause of endomyocardial fibrosis by way of in silico proteomics and analytical chemistry., PMID:19823676
p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling., PMID:19332537
Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenal., PMID:19054759
Ultrastructural and biochemical analysis of a new mutation in Chlamydomonas reinhardtii affecting the central pair apparatus., PMID:18157500
Down-regulation of glutaminase C in human hepatocarcinoma cell by diphenylarsinic acid, a degradation product of chemical warfare agents., PMID:17321558
The inter-ring arrangement of the cytosolic chaperonin CCT., PMID:17304242
Characterization and over-expression of chaperonin t-complex proteins in colorectal cancer., PMID:16981251
Substantial CCT activity is required for cell cycle progression and cytoskeletal organization in mammalian cells., PMID:16765944
Sequential ATP-induced allosteric transitions of the cytoplasmic chaperonin containing TCP-1 revealed by EM analysis., PMID:15696173
Expressional patterns of chaperones in ten human tumor cell lines., PMID:15598346
Generation of Arabidopsis protein chips for antibody and serum screening., PMID:14558660
Transcriptional regulation of the cytosolic chaperonin theta subunit gene, Cctq, by Ets domain transcription factors Elk-1, Sap-1a, and Net in the absence of serum response factor., PMID:12788937
Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex., PMID:12502735
Molecular cloning and characterization of a group II chaperonin delta-subunit from soybean., PMID:12153728
Slow axonal transport of the cytosolic chaperonin CCT with Hsc73 and actin in motor neurons., PMID:11933046
Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas., PMID:11857388
Characterisation of the gene encoding a protective antigen from Babesia microti identified it as eta subunit of chaperonin containing T-complex protein 1., PMID:11730795
A constitutive 70 kDa heat-shock protein is localized on the fibres of spindles and asters at metaphase in an ATP-dependent manner: a new chaperone role is proposed., PMID:11716770
Cloning of rabbit Cct6 and the distribution of the Cct complex in mammalian tissues., PMID:10810232
The interaction of the chaperonin tailless complex polypeptide 1 (TCP1) ring complex (TRiC) with ribosome-bound nascent chains examined using photo-cross-linking., PMID:10791973
Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin., PMID:10748209
Disassembly of the cytosolic chaperonin in mammalian cell extracts at intracellular levels of K+ and ATP., PMID:10383429
Subunits of the eukaryotic cytosolic chaperonin CCT do not always behave as components of a uniform hetero-oligomeric particle., PMID:10082421
The chaperone cofactor Hop/p60 interacts with the cytosolic chaperonin-containing TCP-1 and affects its nucleotide exchange and protein folding activities., PMID:9792653
The chaperonin containing TCP-1 (CCT) displays a single-ring mediated disassembly and reassembly cycle., PMID:9563827
Subunit characterization of the Caenorhabditis elegans chaperonin containing TCP-1 and expression pattern of the gene encoding CCT-1., PMID:9434769
Cytosolic factors mediate protein insertion into the peroxisomal membrane., PMID:9305739
The third member of the Tetrahymena CCT subunit gene family, TpCCT alpha, encodes a component of the hetero-oligomeric chaperonin complex., PMID:9337846
Analysis of chaperonin-containing TCP-1 subunits in the human keratinocyte two-dimensional protein database: further characterisation of antibodies to individual subunits., PMID:8982604
gamma-Tubulin in mammalian cells: the centrosomal and the cytosolic forms., PMID:8718679
Cucumber T-complex protein. Molecular cloning, bacterial expression and characterization within a 22-S cytosolic complex in cotyledons and hypocotyls., PMID:8631317
Molecular chaperones and the centrosome. A role for HSP 73 in centrosomal repair following heat shock treatment., PMID:8557693
Molecular chaperones and the centrosome. A role for TCP-1 in microtubule nucleation., PMID:8557692
The 60 kDa heat shock proteins in the hyperthermophilic archaeon Sulfolobus shibatae., PMID:7473746
Molecular analysis of Caenorhabditis elegans tcp-1, a gene encoding a chaperonin protein., PMID:7758963
Cytoplasmic chaperonin complexes enter neurites developing in vitro and differ in subunit composition within single cells., PMID:7615668
The eighth Cct gene, Cctq, encoding the theta subunit of the cytosolic chaperonin containing TCP-1., PMID:7890169
For research use only. Not for human or drug use.
