Catalog No.
PHA12901
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MEIS1 (Ser62-Lys180).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Homeobox protein Meis1, MEIS1
Purification
Purified by antigen affinity column.
Accession
O00470
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Hoxa9/meis1-transgenic zebrafish develops acute myeloid leukaemia-like disease with rapid onset and high penetrance., PMID:36285442
Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia., PMID:36005562
Meis1 plays roles in cortical development through regulation of cellular proliferative capacity in the embryonic cerebrum., PMID:35718449
The homeodomain transcription factor MEIS1 triggers chemokine expression and is involved in CD8+ T-lymphocyte infiltration in early stage ovarian cancer., PMID:29802738
GPR56 contributes to the development of acute myeloid leukemia in mice., PMID:27063597
Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l., PMID:23138183
A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer., PMID:21858198
The role of meis1 in primitive and definitive hematopoiesis during zebrafish development., PMID:21048033
Platelets play an essential role in separating the blood and lymphatic vasculatures during embryonic angiogenesis., PMID:20203303
Immunohistochemical demonstration of angiogenesis-associated homeobox proteins in canine vascular tumours., PMID:19505696
Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome., PMID:18195096
Differentially expressed genes are marked by histone 3 lysine 9 trimethylation in human cancer cells., PMID:17968314
5' hox genes and meis 1, a hox-DNA binding cofactor, are expressed in the adult mouse epididymis., PMID:12533430