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InVivoMAb Anti-pan SARS-CoV-2 RBD Antibody (1H1)

Catalog #:   VVV00302 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: Neutralization
Accession: P0DTC2
Overview

Catalog No.

VVV00302

Species reactivity

SARS-CoV-2

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Spike glycoprotein, S glycoprotein, E2, Peplomer protein, RBD, Spike protein S1, S, Receptor-Binding Domain, SARS-CoV-2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P0DTC2

Applications

Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

1H1

Data Image
References

Allostery Links hACE2 Binding, Pan-variant Neutralization and Helical Extension in the SARS-CoV-2 Spike Protein., PMID:40447075

Development of bivalent RBD adapted COVID-19 vaccines for broad sarbecovirus immunity., PMID:40442110

Cross-reactive sarbecovirus antibodies induced by mosaic RBD nanoparticles., PMID:40402246

An RBD-Fc mucosal vaccine provides variant-proof protection against SARS-CoV-2 in mice and hamsters., PMID:40383816

AI designed, mutation resistant broad neutralizing antibodies against multiple SARS-CoV-2 strains., PMID:40319133

A SARS-CoV and SARS-CoV-2 RBD Heterodimer Vaccine Candidate., PMID:40317517

Self-assembled epitope-based nanoparticles targeting the SARS-CoV-2 spike protein enhanced the immune response and induced potential broad neutralizing activity., PMID:40270771

Anti-S2 antibodies responsible for the SARS-CoV-2 infection-induced serological cross-reactivity against MERS-CoV and MERS-related coronaviruses., PMID:40226608

Immunogenicity and safety of monovalent and bivalent SARS-CoV-2 variant adapted RBD-based protein booster vaccines in adults previously immunized with different vaccine platforms: A phase II/III, randomized clinical trial., PMID:40179522

Regional dynamics and mechanisms behind SARS-CoV-2 XDV.1 prevalence in Chongqing via genomic surveillance and molecular insights., PMID:40139569

Development of Receptor-Integrated Magnetically Labeled Liposomes for Investigating SARS-CoV-2 Fusion Interactions., PMID:39925203

Immune evasion of Omicron variants JN.1, KP.2, and KP.3 to the polyclonal and monoclonal antibodies from COVID-19 convalescents and vaccine recipients., PMID:39864525

Cross-reactive sarbecovirus antibodies induced by mosaic RBD-nanoparticles., PMID:39803445

Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches., PMID:39584380

A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice., PMID:39561781

Engineered bispecific antibodies with enhanced breadth and potency against SARS-CoV-2 variants and SARS-related coronaviruses., PMID:39520579

Broad cross neutralizing antibodies against sarbecoviruses generated by SARS-CoV-2 infection and vaccination in humans., PMID:39438493

Chemical Proteomics Approaches for Screening Small Molecule Inhibitors Covalently Binding to SARS-Cov-2., PMID:39410782

Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1., PMID:39375326

Nanomechanical footprint of SARS-CoV-2 variants in complex with a potent nanobody by molecular simulations., PMID:39351797

Structure-guided in vitro evolution of nanobodies targeting new viral variants., PMID:39325826

Individuals carrying the HLA-B*15 allele exhibit favorable responses to COVID-19 vaccines but are more susceptible to Omicron BA.5.2 and XBB.1.16 infection., PMID:39257586

A head-to-head comparison of humoral and cellular immune responses of five COVID-19 vaccines in adults in China., PMID:39234239

Protective RBD-dimer vaccines against SARS-CoV-2 and its variants produced in glycoengineered Pichia pastoris., PMID:39213280

Pan-beta-coronavirus subunit vaccine prevents SARS-CoV-2 Omicron, SARS-CoV, and MERS-CoV challenge., PMID:39189731

A Click-Type Enzymatic Method for Antigen-Adjuvant Conjugation., PMID:39177201

Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2., PMID:39071888

Universal subunit vaccine protects against multiple SARS-CoV-2 variants and SARS-CoV., PMID:39054338

Preparation and immunological activity evaluation of an intranasal protein subunit vaccine against ancestral and mutant SARS-CoV-2 with curdlan sulfate/O-linked quaternized chitosan nanoparticles as carrier and adjuvant., PMID:39002905

Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes., PMID:38848216

Immune responses and reinfection of SARS-CoV-2 Omicron variant in patients with lung cancer., PMID:38837354

Mosaic RBD nanoparticle elicits immunodominant antibody responses across sarbecoviruses., PMID:38748880

Inducing Long Lasting B Cell and T Cell Immunity Against Multiple Variants of SARS-CoV-2 Through Mutant Bacteriophage Qβ-Receptor Binding Domain Conjugate., PMID:38733291

Safety and immunogenicity of the SARS-CoV-2 LYB001 RBD-based VLP vaccine (CHO cell) phase 1 in Chinese adults: a randomized, double-blind, positive-parallel-controlled study., PMID:38695310

A chimeric adenovirus-vectored vaccine based on Beta spike and Delta RBD confers a broad-spectrum neutralization against Omicron-included SARS-CoV-2 variants., PMID:38680520

When Should I Get My Next COVID-19 Vaccine? Data From the Surveillance of Responses to COVID-19 Vaccines in Systemic Immune-Mediated Inflammatory Diseases (SUCCEED) Study., PMID:38621797

Rapid isolation of pan-neutralizing antibodies against Omicron variants from convalescent individuals infected with SARS-CoV-2., PMID:38510237

The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis., PMID:38454157

N-glycosylation of the SARS-CoV-2 spike protein at Asn331 and Asn343 is involved in spike-ACE2 binding, virus entry, and regulation of IL-6., PMID:38444370

Asialoglycoprotein receptor 1 promotes SARS-CoV-2 infection of human normal hepatocytes., PMID:38355848

Safety and Immunogenicity After Primary and Booster Inactivated SARS-Cov-2 Vaccination in Patients with Autoimmune Liver Diseases., PMID:38343613

A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity., PMID:38316751

Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants., PMID:38287016

Caveats of chimpanzee ChAdOx1 adenovirus-vectored vaccines to boost anti-SARS-CoV-2 protective immunity in mice., PMID:38280035

Site-directed neutralizing antibodies targeting structural sites on SARS-CoV-2 spike protein., PMID:38128698

Mosaic RBD Nanoparticles Elicit Protective Immunity Against Multiple Human Coronaviruses in Animal Models., PMID:38105421

Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies., PMID:38096415

Deep immunoglobulin repertoire sequencing depicts a comprehensive atlas of spike-specific antibody lineages shared among COVID-19 convalescents., PMID:38044868

Vaccine-mediated protection against Merbecovirus and Sarbecovirus challenge in mice., PMID:37858337

Protection of the receptor binding domain (RBD) dimer against SARS-CoV-2 and its variants., PMID:37843372

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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InVivoMAb Anti-pan SARS-CoV-2 RBD Antibody (1H1) [VVV00302]
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