Catalog No.
RHN09601
Species reactivity
Human
Host species
Mouse
Isotype
VHH-mFc
Clonality
Monoclonal
Target
Electroneutral Na/HCO(3) cotransporter, Sodium bicarbonate cotransporter 3, NBC3, Sodium bicarbonate cotransporter 2, NBCn1, Solute carrier family 4 member 7, Bicarbonate transporter, SLC4A6, NBC2, SBC2, Sodium bicarbonate cotransporter 2b, NBC2B, BT, SLC4A7
Concentration
0.44 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y6M7
Applications
ELISA
Form
Liquid
Storage buffer
30 mM histidine pH 5.8, 10% sucrose, 0.02% Tween 80
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1974
Antibodies toward Na+,HCO3--cotransporter NBCn1/SLC4A7 block net acid extrusion and cause pH-dependent growth inhibition and apoptosis in breast cancer., PMID:38310186
Searching for serum protein markers of equine squamous gastric disease using gel electrophoresis and mass spectrometry., PMID:30636330
Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes., PMID:27609814
Role of Sodium Bicarbonate Cotransporters in Intracellular pH Regulation and Their Regulatory Mechanisms in Human Submandibular Glands., PMID:26375462
Reduced sarcolemmal expression and function of the NBCe1 isoform of the Na⁺-HCO₃⁻ cotransporter in hypertrophied cardiomyocytes of spontaneously hypertensive rats: role of the renin-angiotensin system., PMID:24253522
Neuronal expression of sodium/bicarbonate cotransporter NBCn1 (SLC4A7) and its response to chronic metabolic acidosis., PMID:20147654
Sodium/bicarbonate cotransporter NBCn1/slc4a7 increases cytotoxicity in magnesium depletion in primary cultures of hippocampal neurons., PMID:19170751
Electrogenic NBCe1 (SLC4A4), but not electroneutral NBCn1 (SLC4A7), cotransporter undergoes cholinergic-stimulated endocytosis in salivary ParC5 cells., PMID:18815229
Antibody-independent localization of the electroneutral Na+-HCO3- cotransporter NBCn1 (slc4a7) in mice., PMID:18077606
Use of a new polyclonal antibody to study the distribution and glycosylation of the sodium-coupled bicarbonate transporter NCBE in rodent brain., PMID:18061361
Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissues., PMID:17715183
Time course of auditory impairment in mice lacking the electroneutral sodium bicarbonate cotransporter NBC3 (slc4a7)., PMID:16181686
An anti-NH2-terminal antibody localizes NBCn1 to heart endothelia and skeletal and vascular smooth muscle cells., PMID:16126812
Sodium coupled bicarbonate transporters in the kidney, an update., PMID:15283764
Immunoelectron microscopic localization of NBC3 sodium-bicarbonate cotransporter in rat kidney., PMID:10662737