Catalog No.
RHK85401
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
TEM8, ATR, Anthrax toxin receptor 1, ANTXR1, Tumor endothelial marker 8
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H6X2
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1962
One Health Assessment of Bacillus anthracis Incidence and Detection in Anthrax-Endemic Areas of Pakistan., PMID:37894120
Cancer cell survival depends on collagen uptake into tumor-associated stroma., PMID:36400786
Targeted silencing of TEM8 suppresses non‑small cell lung cancer tumor growth via the ERK/Bcl‑2 signaling pathway., PMID:34165155
TEM8/ANTXR1-specific CAR T cells mediate toxicity in vivo., PMID:31622431
MSLN (Mesothelin), ANTXR1 (TEM8), and MUC3A are the potent antigenic targets for CAR T cell therapy of gastric adenocarcinoma., PMID:30260046
Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release., PMID:29863500
Deadly DAaRTS destroy cancer cells via a tumor microenvironment-mediated trigger., PMID:29863494
Cell autonomous ANTXR1-mediated regulation of extracellular matrix components in primary fibroblasts., PMID:28011198
In situ targeting TEM8 via immune response and polypeptide recognition by wavelength-modulated surface plasmon resonance biosensor., PMID:26822761
Immuno-PET imaging of tumor endothelial marker 8 (TEM8)., PMID:24984190
Targeted silencing of anthrax toxin receptors protects against anthrax toxins., PMID:24742682
Mutations in ANTXR1 cause GAPO syndrome., PMID:23602711
Selective blockade of tumor angiogenesis., PMID:22617387
TEM8/ANTXR1 blockade inhibits pathological angiogenesis and potentiates tumoricidal responses against multiple cancer types., PMID:22340594
TEM8 targeted cancer therapy., PMID:22023048
Tumor endothelial marker 8 expression in triple-negative breast cancer., PMID:21965755
Tumor endothelial marker 8 amplifies canonical Wnt signaling in blood vessels., PMID:21829615
Expression pattern of tumor endothelial marker 8 protein in gallbladder carcinomas., PMID:21545221
The cell surface structure of tumor endothelial marker 8 (TEM8) is regulated by the actin cytoskeleton., PMID:21129411
Heterodimeric integrin complexes containing beta1-integrin promote internalization and lethality of anthrax toxin., PMID:20713715
Endosomal recycling regulates Anthrax Toxin Receptor 1/Tumor Endothelial Marker 8-dependent cell spreading., PMID:20382142
Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma., PMID:18931684
Antitumor activities of TEM8-Fc: an engineered antibody-like molecule targeting tumor endothelial marker 8., PMID:17925540
Anthrax toxin receptor 2-dependent lethal toxin killing in vivo., PMID:17054395
Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton., PMID:16762926
The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin., PMID:16564009
[Expression of ATR-Fc fusion protein in CHO cells]., PMID:16285529
ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection., PMID:15689409
Tumour endothelial marker 8 (TEM-8) in human colon cancer and its association with tumour progression., PMID:15498639
Upregulation of tumour endothelial marker-8 by interleukin-1beta and its impact in IL-1beta induced angiogenesis., PMID:15202019
For research use only. Not for human or drug use.
