Anti-Human SPARC/Osteonectin Antibody (SAA1953)

Catalog No.

RHC40901

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, lambda

Clonality

Monoclonal

Target

Secreted protein acidic and rich in cysteine, Basement-membrane protein 40, BM-40, Osteonectin, ON, SPARC

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P09486

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1953

Navigating the clinical challenges of zolbetuximab in patients with claudin positive advanced gastric cancer., PMID:40466467

Concomitant anti-CGRP and immunomodulatory treatments in patients with migraine: towards integrated management strategies., PMID:40461909

Pre-diagnostic Demographic, Lifestyle, and Health History Factors in Association with Secreted Protein Acidic and Rich in Cysteine (SPARC) Expression in Colorectal Cancer Tissue., PMID:40417350

ROCKET: a phase 3 program evaluating the efficacy and safety of rocatinlimab in moderate-to-severe atopic dermatitis., PMID:40012373

Setting higher standards for migraine prevention: A position statement of the International Headache Society., PMID:39980456

Using mathematical modelling and AI to improve delivery and efficacy of therapies in cancer., PMID:39972158

Switching between anti-CGRP monoclonal antibodies in migraine prophylaxis., PMID:39884968

The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome., PMID:39859144

Dual Targeting Biomimetic Carrier-Free Nanosystems for Photo-Chemotherapy of Rheumatoid Arthritis via Macrophage Apoptosis and Re-Polarization., PMID:39840927

SON-1010: an albumin-binding IL-12 fusion protein that improves cytokine half-life, targets tumors, and enhances therapeutic efficacy., PMID:39697343

Predicting success with reduced dosing frequency of tralokinumab in patients with moderate-to-severe atopic dermatitis., PMID:39657020

Identification of high-performing antibodies for SPARC-related modular calcium-binding protein 1 (SMOC-1) for use in Western Blot and immunoprecipitation., PMID:39291144

An interdisciplinary perspective on peripheral drivers of pain in rheumatoid arthritis., PMID:39242949

A First-in-Human Study of Cinrebafusp Alfa, a HER2/4-1BB Bispecific Molecule, in Patients with HER2-Positive Advanced Solid Malignancies., PMID:39235868

Diagnostic value of anti-VZV IgG in neurological diseases among varicella unvaccinated individuals., PMID:39085748

Pharmacokinetics and pharmacodynamics of itepekimab in adults with moderate-to-severe atopic dermatitis: Results from two terminated phase II trials., PMID:39077906

CAFs-Associated Genes (CAFGs) in Pancreatic Ductal Adenocarcinoma (PDAC) and Novel Therapeutic Strategy., PMID:38892190

Pituitary cyclase-activating polypeptide targeted treatments for the treatment of primary headache disorders., PMID:38887982

Antibody-mediated autoimmunity in symptom-based disorders: position statement and proceedings from an international workshop., PMID:38873615

Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy., PMID:38742767

Cancer-associated fibroblast activation predicts progression, metastasis, and prognosis of cutaneous squamous cell carcinoma., PMID:38648387

An economic evaluation of eptinezumab for the preventive treatment of migraine in the UK, with consideration for natural history and work productivity., PMID:38637754

An ELISA Using Synthetic Mycolic Acid-Based Antigens with DIVA Potential for Diagnosing Johne's Disease in Cattle., PMID:38539946

Normalizing granuloma vasculature and matrix improves drug delivery and reduces bacterial burden in tuberculosis-infected rabbits., PMID:38530888

Phase I Study of GS-3583, an FMS-like Tyrosine Kinase 3 Agonist Fc Fusion Protein, in Patients with Advanced Solid Tumors., PMID:38295150

[Evaluation of the predictive effect of PD-L1 expression on survival in early triple-negative breast cancer]., PMID:37968080

Widespread amyloid aggregates formation by Zika virus proteins and peptides., PMID:37937856

SPARC Is a Novel Positive Immunohistochemical Marker of Epithelioid Mesothelioma to Differentiate It From Lung Adenocarcinoma and/or Squamous Cell Carcinoma., PMID:37899530

Tralokinumab Provides Clinically Meaningful Responses at Week 16 in Adults with Moderate-to-Severe Atopic Dermatitis Who Do Not Achieve IGA 0/1., PMID:37804473

Tralokinumab Efficacy Over 1 Year in Adults with Moderate-to-Severe Atopic Dermatitis: Pooled Data from Two Phase III Trials., PMID:37682422

NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy., PMID:37503127

Yield of Serial Testing for Tuberculosis Exposure in Patients With Inflammatory Bowel Diseases: One Test is Not Enough., PMID:37331412

GRAd-COV2 vaccine provides potent and durable humoral and cellular immunity to SARS-CoV-2 in randomized placebo-controlled phase 2 trial., PMID:37315558

Reverse-QTY code design of active human serum albumin self-assembled amphiphilic nanoparticles for effective anti-tumor drug doxorubicin release in mice., PMID:37186820

Utilization of Treat-to-Target Monitoring Colonoscopy After Treatment Initiation in the US-Based Study of a Prospective Adult Research Cohort With Inflammatory Bowel Disease., PMID:37053548

Multicenter, prospective, phase II study of maintenance bevacizumab for children and adults with NF2-related schwannomatosis and progressive vestibular schwannoma., PMID:37010875

Identification of key genes in colorectal cancer diagnosis by co-expression analysis weighted gene co-expression network analysis., PMID:36931200

Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice., PMID:36898734

Randomized, Double-Blind, Placebo-Controlled Trial of MUC1 Peptide Vaccine for Prevention of Recurrent Colorectal Adenoma., PMID:36892581

Second-Line Biologic Therapy Following Tumor Necrosis Factor Antagonist Failure: A Real-World Propensity Score-Weighted Analysis., PMID:36787837

Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy., PMID:36747853

Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models., PMID:36724255

Efficacy and Safety of Lebrikizumab in Combination With Topical Corticosteroids in Adolescents and Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial (ADhere)., PMID:36630140

Evaluation of human platelet granules by structured illumination laser fluorescence microscopy., PMID:36572649

Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial., PMID:36116481

Safety of tralokinumab in adult patients with moderate-to-severe atopic dermatitis: pooled analysis of five randomized, double-blind, placebo-controlled phase II and phase III trials., PMID:36082590

Glypican-3 (GPC3) is associated with MCPyV-negative status and impaired outcome in Merkel cell carcinoma., PMID:35937502

Splenic clearance of rigid erythrocytes as an inherited mechanism for splenomegaly and natural resistance to malaria., PMID:35843175

A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma., PMID:35833850

High-throughput analysis of amniotic fluid proteins associated with histological chorioamnionitis in preterm premature rupture of membranes using an antibody-based microarray., PMID:35792516

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