Catalog No.
RHF70701
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Lipocalin-2, Neutrophil gelatinase-associated lipocalin, Oncogene 24p3, NGAL, HNL, Siderocalin, LCN2, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, p25
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P80188
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1951
Dynamics of antimicrobial proteins' expression and their bactericidal activity in mouse milk., PMID:40345232
Chitinase 3-like protein 1 deficiency ameliorates drug-induced acute liver injury by inhibition of neutrophil recruitment through lipocalin-2., PMID:40196357
Antibody-free LC-HRMS/MS method for simultaneous quantification of NGAL, CRP and SAA in serum from sepsis patients., PMID:39900142
LCN2 blockade mitigating metabolic dysregulation and redefining appetite control in type 2 diabetes., PMID:39808380
Deficiency of neutrophil gelatinase-associated lipocalin elicits a hemophilia-like bleeding and clotting disorder in mice., PMID:39693621
Serum Neutrophil Biomarkers to Predict Crohn's Disease Progression and Infliximab Treatment Outcomes., PMID:39648597
Lipocalin-2 Serum Levels in Rheumatoid Arthritis Patients Treated with Adalimumab and Its Correlation with Proinflammatory Factors., PMID:39403549
Lipocalin-2 drives neuropsychiatric and cutaneous disease in MRL/lpr mice., PMID:39399497
Microbial chaperonin 60 inhibits osteoclast differentiation by interfering with RANK/RANKL binding and overexpression of lipocalin2., PMID:39303785
Lipocalin-2 as a fundamental protein in type 2 diabetes and periodontitis in mice., PMID:39189666
C/EBPδ Mediates Immunity to Renal Autoinflammatory Disorders in a Stage-specific Manner., PMID:39082925
Associations between Microglia and Astrocytic Proteins and Tau Biomarkers across the Continuum of Alzheimer's Disease., PMID:39062786
Detection strip of anti-NGAL antibody coupled with fluorescent microspheres-A novel tool for reliable and accurate prediction of renal injury., PMID:39038591
Intestinal mRNA expression profiles associated with mucosal healing in ustekinumab-treated Crohn's disease patients: bioinformatics analysis and prospective cohort validation., PMID:38926732
Identifying hub genes in response to ustekinumab and the impact of ustekinumab treatment on fibrosis in Crohn's disease., PMID:38840917
Spinal lipocalin 2 as a factor in the development of central post-stroke pain., PMID:38705557
Characterization of cells expressing lipocalin-2 (LCN2) as a reporter., PMID:38696838
Disposable label-free electrochemical immunosensor based on gold nanoparticles-Prussian blue for neutrophil gelatinase-associated lipocalin detection in urine samples., PMID:38555767
Noninvasive Markers of Inflammation and Protein Loss Augment Diagnosis of Pediatric Celiac Disease., PMID:38483287
Neutrophil-Associated Proteins as Novel Biomarkers Elevated in Cerebrospinal Fluid of Patients With Neurosyphilis., PMID:38427829
The Role of Serological Markers in the Prediction of Disease Course and Response to Therapy in Inflammatory Bowel Disease., PMID:38073917
Identification of Diagnosis and Typological Characteristics Associated with Ferroptosis for Ulcerative Colitis via Bioinformatics and Machine Learning., PMID:37957905
Lipocalin-2: a therapeutic target to overcome neurodegenerative diseases by regulating reactive astrogliosis., PMID:37779143
Transcriptome analysis of renal ischemia/reperfusion (I/R) injury in BAFF and BAFF-R deficient mice., PMID:37751458
[Lipocalin 2 induces self-limited inhibition of osteoblast differentiation of mesenchymal stem cells]., PMID:37712270
Up-regulation of LCN2 in the anterior cingulate cortex contributes to neural injury-induced chronic pain., PMID:37362002
Socs3 expression in myeloid cells modulates the pathogenesis of dextran sulfate sodium (DSS)-induced colitis., PMID:37283760
LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia., PMID:36973755
Protective Role for Smooth Muscle Cell Hepcidin in Abdominal Aortic Aneurysm., PMID:36951059
Lipocalin-2 Is a Key Regulator of Neuroinflammation in Secondary Traumatic and Ischemic Brain Injury., PMID:36508119
Lcn2 mediates adipocyte-muscle-tumor communication and hypothermia in pancreatic cancer cachexia., PMID:36243318
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD., PMID:35473441
Glioma-derived exosomes hijack the blood-brain barrier to facilitate nanocapsule delivery via LCN2., PMID:35341902
Principal Component Analysis to Differentiate Patients with Palmoplantar Pustulosis from Those with Palmoplantar Pustular Psoriasis., PMID:35221589
Interleukin-17RA blockade by brodalumab decreases inflammatory pathways in hidradenitis suppurativa skin and serum., PMID:35191018
Astrocytic α2-Na+/K+ ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model., PMID:35171651
Secretory protein beta-lactoglobulin in cattle stable dust may contribute to the allergy-protective farm effect., PMID:35169442
Lipocalin 2 Influences Bone and Muscle Phenotype in the MDX Mouse Model of Duchenne Muscular Dystrophy., PMID:35055145
Development of a europium nanoparticles lateral flow immunoassay for NGAL detection in urine and diagnosis of acute kidney injury., PMID:35031018
Structural plasticity in the loop region of engineered lipocalins with novel ligand specificities, so-called Anticalins., PMID:34988429
A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis., PMID:34921145
NGAL as a Potential Target in Tumor Microenvironment., PMID:34830212
Neutrophil Gelatinase-Associated Lipocalin From Macrophages Plays a Critical Role in Renal Fibrosis Via the CCL5 (Chemokine Ligand 5)-Th2 Cells-IL4 (Interleukin 4) Pathway., PMID:34794340
RTEC-intrinsic IL-17-driven inflammatory circuit amplifies antibody-induced glomerulonephritis and is constrained by Regnase-1., PMID:34236049
Lipocalin 2 expression promotes tumor progression and therapy resistance by inhibiting ferroptosis in colorectal cancer., PMID:34146401
Overexpression of Lipocalin-2 Inhibits Proliferation and Invasiveness of Human Glioblastoma Multiforme Cells by Activating ERK Targeting Cathepsin D Expression., PMID:34062746
Bovine Holo-Beta-Lactoglobulin Cross-Protects Against Pollen Allergies in an Innate Manner in BALB/c Mice: Potential Model for the Farm Effect., PMID:33746954
Lipocalin-2 in Diabetic Complications of the Nervous System: Physiology, Pathology, and Beyond., PMID:33613327
Ranolazine alleviates contrast-associated acute kidney injury through modulation of calcium independent oxidative stress and apoptosis., PMID:33352171
An immune-based biomarker signature is associated with mortality in COVID-19 patients., PMID:33232303
For research use only. Not for human or drug use.
