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Anti-Human GNLY/Granulysin Antibody (SAA1936)

Catalog #:   RHD54401 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: P22749
Overview

Catalog No.

RHD54401

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

T-cell activation protein 519, Protein NKG5, TLA519, Lymphokine LAG-2, GNLY, NKG5, Granulysin, LAG2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P22749

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1936

Data Image
References

Novel diagnostic biomarker and immune profiling of GPR56+ B cell subsets in systemic lupus erythematosus., PMID:40311320

GNLY+CD8+ T cells bridge premature aging and persistent inflammation in people living with HIV., PMID:40135938

Integrating single-cell RNA and T cell/B cell receptor sequencing with mass cytometry reveals dynamic trajectories of human peripheral immune cells from birth to old age., PMID:39881000

Human cancer cells xenografts to assess the efficacy of granulysin-based therapeutics., PMID:39863395

Gene Expression Profiling of the Peritumoral Immune Cell Infiltrate of Penile Squamous Cell Carcinomas., PMID:39596210

T-cell Mediated Rejection Associated Microvascular Inflammation in the Allograft Kidney: RNAseq Analysis Using the Banff Human Organ Transplant Gene Panel., PMID:39033507

Identification of different functions of CD8+ T cell subpopulations by a novel monoclonal antibody., PMID:38922845

Granulysin-mediated reduction of PDZRN3 induces Cx43 gap junctions activity exacerbating skin damage in trichloroethylene hypersensitivity syndrome., PMID:38471344

Differentially Expressed Genes Involved in Primary Resistance to Immunotherapy in Patients with Advanced-Stage Pulmonary Cancer., PMID:38396726

Novel transcriptomic signatures associated with premature kidney allograft failure., PMID:37660534

Single-cell transcriptome analysis and protein profiling reveal broad immune system activation in IgG4-related disease., PMID:37561593

Autoimmune thyroid disease disrupts immune homeostasis in the endometrium of unexplained infertility women-a single-cell RNA transcriptome study during the implantation window., PMID:37501789

Blocking of programmed cell death-ligand 1 (PD-L1) expressed on endothelial cells promoted the recruitment of CD8+IFN-γ+ T cells in atherosclerosis., PMID:36867228

Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data., PMID:36195867

Immune features of COVID-19 convalescent individuals revealed by a single-cell RNA sequencing., PMID:35453072

The Trifecta Study: Comparing Plasma Levels of Donor-derived Cell-Free DNA with the Molecular Phenotype of Kidney Transplant Biopsies., PMID:35058354

Artificial Neural Networks Predicted the Overall Survival and Molecular Subtypes of Diffuse Large B-Cell Lymphoma Using a Pancancer Immune-Oncology Panel., PMID:34945004

Chronic Active Antibody-Mediated Rejection Is Associated With the Upregulation of Interstitial But Not Glomerular Transcripts., PMID:34616398

A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 Patients., PMID:34322127

The Role of IL-13, IL-15 and Granulysin in the Pathogenesis of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis., PMID:33560872

Granzyme B-expressing γδ-T and NK cells as a predictor of clinical pregnancy failure in patients with unexplained repeated implantation failure., PMID:33540297

γδ T cells suppress Plasmodium falciparum blood-stage infection by direct killing and phagocytosis., PMID:33432229

Production of a Granulysin-Based, Tn-Targeted Cytolytic Immunotoxin Using Pulsed Electric Field Technology., PMID:32859066

The cytotoxic molecule granulysin is capable of inducing either chemotaxis or fugetaxis in dendritic cells depending on maturation: a role for Vδ2+ γδ T cells in the modulation of immune response to tumour?, PMID:32794189

Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma., PMID:32042196

Reverse transcriptase multiplex ligation-dependent probe amplification in endomyocardial biopsies for the diagnosis of cardiac allograft rejection., PMID:31822443

[Mechanisms of Severe Cutaneous Adverse Reactions and a New Treatment Strategy]., PMID:31787645

Activated cytotoxic T cells within zoonotic cutaneous leishmaniasis lesions., PMID:30997749

Cytotoxic CD8+ T cells recognize and kill Plasmodium vivax-infected reticulocytes., PMID:30038217

A Case Report and Literature Review of Scrub Typhus With Acute Abdomen and Septic Shock in a Child-The Role of Leukocytoclastic Vasculitis and Granulysin., PMID:29697421

Randomized, controlled trial of TNF-α antagonist in CTL-mediated severe cutaneous adverse reactions., PMID:29400697

Review: The transcripts associated with organ allograft rejection., PMID:29178397

Review of Toxic Epidermal Necrolysis., PMID:27999358

Evidence for CD16a-Mediated NK Cell Stimulation in Antibody-Mediated Kidney Transplant Rejection., PMID:27906829

Evaluation of serum granulysin as a potential biomarker for nasopharyngeal carcinoma., PMID:26751807

The molecular landscape of antibody-mediated kidney transplant rejection: evidence for NK involvement through CD16a Fc receptors., PMID:25787894

Acquired Idiopathic Generalized Anhidrosis: An Immunohistopathological Investigation of Peri-glands Infiltrated with Immunoreactive Cells., PMID:25519938

The peripheral blood transcriptome reflects variations in immunity traits in swine: towards the identification of biomarkers., PMID:24341289

Ganoderma lucidum stimulates NK cell cytotoxicity by inducing NKG2D/NCR activation and secretion of perforin and granulysin., PMID:23803412

Granule exocytosis of granulysin and granzyme B as a potential key mechanism in vaccine-induced immunity in cattle against the nematode Ostertagia ostertagi., PMID:23478322

Distinguishing between erythema multiforme major and Stevens-Johnson syndrome/toxic epidermal necrolysis immunopathologically., PMID:22458564

Granulysin Expression in Lymphocytes that Populate the Peripheral Blood and the Myocardium after an Acute Coronary Event., PMID:21967803

Pretreatment serum level of 15-kDa granulysin might have a prognostic value in patients with diffuse large B cell lymphoma., PMID:21540579

Rapid immunochromatographic test for serum granulysin is useful for the prediction of Stevens-Johnson syndrome and toxic epidermal necrolysis., PMID:21507517

[The purification of recombinated granulysin and the preparation of its monoclonal antibody]., PMID:20734534

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin., PMID:20660289

GLS/IL-12-modified Mycobacterium smegmatis as a novel anti-tuberculosis immunotherapeutic vaccine., PMID:19861007

Characterization of effector functions of human peptide-specific CD4+ T-cell clones for an intracellular pathogen., PMID:18588932

Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans, and activation of this pathway is defective in HIV patients., PMID:17038537

Construction of a eukaryotic expression system for granulysin and its protective effect in mice infected with Mycobacterium tuberculosis., PMID:17005788

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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For research use only. Not for human or drug use.

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Anti-Human GNLY/Granulysin Antibody (SAA1936) [RHD54401]
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