Catalog No.
RHD03501
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
FBP, FOLR2, Folate receptor beta, Placental folate-binding protein, Folate receptor, fetal/placental, FR-beta, Folate receptor 2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P14207
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1933
Mirvetuximab soravtansine-gynx: first antibody/antigen-drug conjugate (ADC) in advanced or recurrent ovarian cancer., PMID:38101816
Recent Advances in Folates and Autoantibodies against Folate Receptors in Early Pregnancy and Miscarriage., PMID:38068740
FDA Approval Summary: Mirvetuximab Soravtansine-Gynx for FRα-Positive, Platinum-Resistant Ovarian Cancer., PMID:37212825
Folate Receptor Beta as a Direct and Indirect Target for Antibody-Based Cancer Immunotherapy., PMID:34070369
Folate receptor-targeted positron emission tomography of experimental autoimmune encephalomyelitis in rats., PMID:31796042
Genetic assessment and folate receptor autoantibodies in infantile-onset cerebral folate deficiency (CFD) syndrome., PMID:29661558
High-affinity FRβ-specific CAR T cells eradicate AML and normal myeloid lineage without HSC toxicity., PMID:26898190
Atypical Activin A and IL-10 Production Impairs Human CD16+ Monocyte Differentiation into Anti-Inflammatory Macrophages., PMID:26729812
Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile., PMID:25319955
Importance of folate-homocysteine homeostasis during early embryonic development., PMID:18067451