Catalog No.
RHN08401
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
KIAA1133, RNF203, RING-type E3 ubiquitin transferase ZNRF3, ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, E3 ubiquitin-protein ligase ZNRF3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9ULT6
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1919
Structure-Guided Development of Chemically Tailored Peptide Binders of RNF43/ZNRF3 to Enable Versatile Design of Membrane Protein-Targeting PROTACs., PMID:40000409
Coactivation of Tie2 and Wnt signaling using an antibody-R-spondin fusion potentiates therapeutic angiogenesis and vessel stabilization in hindlimb ischemia., PMID:39607038
Get your receptors in a knot with new Wnt signaling agonists., PMID:38906109
Targeted protein degradation systems to enhance Wnt signaling., PMID:38847394
Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth., PMID:38056465
Antibody targeting of E3 ubiquitin ligases for receptor degradation., PMID:36131013
Roadmap for Optimizing and Broadening Antibody-Based PROTACs for Degradation of Cell Surface Proteins., PMID:35481357
Longitudinal change of genetic variations in cetuximab-treated metastatic colorectal cancer., PMID:34315006
Unlike LGR4, LGR5 potentiates Wnt-β-catenin signaling without sequestering E3 ligases., PMID:33262293
Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling., PMID:31914456
Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells., PMID:30664649
Whole exome sequencing to identify genetic markers for trastuzumab-induced cardiotoxicity., PMID:29247589
Molecular genetics and targeted therapy of WNT-related human diseases (Review)., PMID:28731148
For research use only. Not for human or drug use.
