Catalog No.
RHN08101
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Prion-like protein doppel, PrPLP, PRND, Prion protein 2, DPL
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UKY0
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1916
Prion protein 2 (dublet) gene (PRND): role in ovine semen capacitation, cryopreservation and fertility., PMID:28442049
Is prnt a pseudogene? Identification of ram Prt in testis and ejaculated spermatozoa., PMID:22937002
Prion protein expression regulates embryonic stem cell pluripotency and differentiation., PMID:21483752
Autophagy and cell death of Purkinje cells overexpressing Doppel in Ngsk Prnp-deficient mice., PMID:19055638
BAX contributes to Doppel-induced apoptosis of prion-protein-deficient Purkinje cells., PMID:17443816
Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes., PMID:16766127
Spatio-developmental distribution of the prion-like protein doppel in Mammalian testis: a comparative analysis focusing on its presence in the acrosome of spermatids., PMID:16421231
Involvement of upstream stimulatory factor in regulation of the mouse Prnd gene coding for Doppel protein., PMID:16297464
Purkinje-cell degeneration in prion protein-deficient mice is associated with a cerebellum-specific Doppel protein species signature., PMID:15862314
The prion protein and its paralogue Doppel affect calcium signaling in Chinese hamster ovary cells., PMID:15788568
A neuronal cell line that does not express either prion or doppel proteins., PMID:15770145
Identification of bovine doppel protein in testis, ovary and ejaculated spermatozoa., PMID:15710203
Selective PrP-like protein, doppel immunoreactivity in dystrophic neurites of senile plaques in Alzheimer's disease., PMID:15305978
Human Doppel and prion protein share common membrane microdomains and internalization pathways., PMID:15203115
Prion and doppel proteins bind to granule cells of the cerebellum., PMID:12446843
Doppel and PrP(C) do not share the same membrane microenvironment., PMID:12387871
Abnormal activation of glial cells in the brains of prion protein-deficient mice ectopically expressing prion protein-like protein, PrPLP/Dpl., PMID:11844868
Expression and structural characterization of the recombinant human doppel protein., PMID:11063595
For research use only. Not for human or drug use.
