Catalog No.
RHN06901
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Semaphorin-B, SEMA4A, SEMAB, Sema B, Semaphorin-4A, SEMB
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H3S1
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1904
Rheumatoid meningitis in the absence of active synovitis: A potential association of semaphorin 4A., PMID:39946854
Markedly upregulated serum semaphorin 4A as a novel activity marker of myasthenia gravis., PMID:38605547
Semaphorin4A promotes lung cancer by activation of NF-κB pathway mediated by PlexinB1., PMID:37901456
Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation., PMID:37205755
Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma., PMID:35134130
Semaphorin 4A antibody alleviates arsenic-induced hepatotoxicity in mice via inhibition of AKT2/NF-κB inflammatory signaling., PMID:33290778
Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner., PMID:32971928
Semaphorin 4A Stabilizes Human Regulatory T Cell Phenotype via Plexin B1., PMID:31236543
Beneficial effects of fingolimod in MS patients with high serum Sema4A levels., PMID:29518148
Semaphorin 4A enhances lung fibrosis through activation of Akt via PlexinD1 receptor., PMID:26648031
Neuropilin 1: function and therapeutic potential in cancer., PMID:24263240
Neuroimmune semaphorin 4A as a drug and drug target for asthma., PMID:23994348
Semaphorin 4A is dynamically regulated during thymocyte development in mice., PMID:23648820
[Aberrant cross talk between immune cells and neural cells in demyelinating disorders]., PMID:22277408
Th1 cells promote neurite outgrowth from cortical neurons via a mechanism dependent on semaphorins., PMID:20946887
Semaphorin 4A induces growth cone collapse of hippocampal neurons in a Rho/Rho-kinase-dependent manner., PMID:15942687
Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice., PMID:15780988
Severe retinal degeneration associated with disruption of semaphorin 4A., PMID:15277503
Structure and function of the immune semaphorin CD100/SEMA4D., PMID:12906260
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2., PMID:12374982