Catalog No.
RHN06601
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
hDC-STAMP, DCSTAMP, DC-STAMP, Dendrocyte-expressed seven transmembrane protein, FIND, TM7SF4, Dendritic cell-specific transmembrane protein, Transmembrane 7 superfamily member 4, IL-four-induced protein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H295
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1901
Histochemical assessment on osteoclasts in long bones of toll-like receptor 2 (TLR2) deficient mice., PMID:37088152
Activin-A Induces Fewer, but Larger Osteoclasts From Monocytes in Both Healthy Controls and Fibrodysplasia Ossificans Progressiva Patients., PMID:32760351
Immune Complex-Driven Generation of Human Macrophages with Anti-Inflammatory and Growth-Promoting Activity., PMID:32434940
Multitarget-based cotreatment with cilostazol and celecoxib synergistically suppresses collagen-induced arthritis in mice by enhancing interleukin-10 expression., PMID:31170675
Host and parasite responses in human diffuse cutaneous leishmaniasis caused by L. amazonensis., PMID:30845223
OC-STAMP promotes osteoclast fusion for pathogenic bone resorption in periodontitis via up-regulation of permissive fusogen CD9., PMID:29533736
Naringenin inhibits osteoclastogenesis through modulation of helper T cells-secreted IL-4., PMID:28834554
DC-STAMP Is an Osteoclast Fusogen Engaged in Periodontal Bone Resorption., PMID:28199142
Microgravity Induction of TRAIL Expression in Preosteoclast Cells Enhances Osteoclast Differentiation., PMID:27142480
E-cadherin is important for cell differentiation during osteoclastogenesis., PMID:26959175
Methanol Extract of Croton Pycnanthus Benth. Inhibits Osteoclast Differentiation by Suppressing the MAPK and NF-κB Signaling Pathways., PMID:25489576
Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation., PMID:25483983
Osteoclast fusion is based on heterogeneity between fusion partners., PMID:24862648
Mechanical vibration inhibits osteoclast formation by reducing DC-STAMP receptor expression in osteoclast precursor cells., PMID:23994170
Impact of docosahexaenoic acid on gene expression during osteoclastogenesis in vitro--a comprehensive analysis., PMID:23945674
The CD40-CD40L axis and IFN-γ play critical roles in Langhans giant cell formation., PMID:22058328
Cells with dendritic cell morphology and immunophenotype, binuclear morphology, and immunosuppressive function in dendritic cell cultures., PMID:22030471
Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP)., PMID:21987375
IkappaBalpha regulates Hes1 in osteoclast differentiation and resorption., PMID:20515776
RANKL induces heterogeneous DC-STAMP(lo) and DC-STAMP(hi) osteoclast precursors of which the DC-STAMP(lo) precursors are the master fusogens., PMID:20039274
Receptor activator of nuclear factor-kappa B ligand induces osteoclast formation in RAW 264.7 macrophage cells via augmented production of macrophage-colony-stimulating factor., PMID:19120972
The role of DC-STAMP in maintenance of immune tolerance through regulation of dendritic cell function., PMID:18653699
Osteoclast stimulatory transmembrane protein (OC-STAMP), a novel protein induced by RANKL that promotes osteoclast differentiation., PMID:18064667
Molecular analysis of RANKL-independent cell fusion of osteoclast-like cells induced by TNF-alpha, lipopolysaccharide, or peptidoglycan., PMID:17171644
RANKL-induced DC-STAMP is essential for osteoclastogenesis., PMID:15452179
For research use only. Not for human or drug use.
