Catalog No.
RHN01801
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Roof plate-specific spondin-2, R-spondin-2, hRspo2, RSPO2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q6UXX9
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1853
Screening, expression, and functional validation of camelid-derived nanobodies targeting RSPO2., PMID:40179630
Targeted protein degradation systems to enhance Wnt signaling., PMID:38847394
Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synoviocytes and disrupting chondrocyte homeostasis via Wnt/β-catenin pathway., PMID:37946278
R-spondin-3 is an oncogenic driver of poorly differentiated invasive breast cancer., PMID:36106661
Robust Colonic Epithelial Regeneration and Amelioration of Colitis via FZD-Specific Activation of Wnt Signaling., PMID:35569814
Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer., PMID:33202731
Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia., PMID:32559496
R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling., PMID:32432544
A polymorphism within the R-spondin 2 gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab: data from FIRE-3 and TRIBE trials., PMID:32305727
Ectonucleotide pyrophosphatase 2 (ENPP2) plays a crucial role in myogenic differentiation through the regulation by WNT/β-Catenin signaling., PMID:31805399
Molecular genetics and targeted therapy of WNT-related human diseases (Review)., PMID:28731148
Secreted factor R-Spondin 2 is involved in refinement of patterning of the mammalian cochlea., PMID:23192966
Wnt signaling genes of murine chromosome 15 are involved in sex-affected pathways of inflammatory arthritis., PMID:22005949
R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation., PMID:18384673
For research use only. Not for human or drug use.
