Catalog No.
RHJ77101
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
EMR2, EGF-like module receptor 2, ADGRE2, EGF-like module-containing mucin-like hormone receptor-like 2, Adhesion G protein-coupled receptor E2, CD312
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UHX3
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1811
Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes., PMID:33488598
Historical Anecdotes and Breakthroughs of Histamine: From Discovery to Date., PMID:32727338
G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody., PMID:31969668
Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies., PMID:31273197
Composition of lymphocyte subpopulations in normal canine lymph nodes., PMID:25512102
Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in gliomas., PMID:25200831
EMR2 receptor ligation modulates cytokine secretion profiles and cell survival of lipopolysaccharide-treated neutrophils., PMID:22035891
F4/80 and the related adhesion-GPCRs., PMID:21952799
Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function., PMID:17928360
Detection of novel leukocyte differentiation antigens on basophils and mast cells by HLDA8 antibodies., PMID:16918507
Identification of the epidermal growth factor-TM7 receptor EMR2 and its ligand dermatan sulfate in rheumatoid synovial tissue., PMID:15693006
Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells., PMID:15498814
The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans., PMID:12829604
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells., PMID:11994511
Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97., PMID:10903844