Catalog No.
RHD47401
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Amphiregulin-associated protein, Midgestation and kidney protein, NEGF2, MDK, ARAP, MK1, Neurite outgrowth-promoting factor 2, MK, Midkine, Neurite outgrowth-promoting protein
Concentration
0.74 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P21741
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1776
Blocking the functional domain of cancer cell surface TIP1 upregulates Midkine via the β-catenin/Wnt signaling pathway., PMID:40533520
A novel pH-sensitive nanoparticles encapsulating anti-PD-1 antibody and MDK-siRNA overcome immune checkpoint blockade resistance in HCC via reshaping immunosuppressive TME., PMID:40380202
Autologous HIV-specific T cell therapy targeting conserved epitopes is well-tolerated in six adults with HIV: an open-label, single-arm phase 1 study., PMID:40374689
A comprehensive analysis of scRNA-Seq and RNA-Seq unveils B cell immune suppression in the AAV-loaded brain., PMID:40044925
Evaluating the Quality of Studies Assessing COVID-19 Vaccine Neutralizing Antibody Immunogenicity., PMID:39591141
An oriented self-assembly biosensor with built-in error-checking for precise midkine detection in cancer diagnosis and prognosis evaluation., PMID:39504885
Midkine: A Cancer Biomarker Candidate and Innovative Therapeutic Approaches., PMID:39257008
Nipocalimab in Early-Onset Severe Hemolytic Disease of the Fetus and Newborn., PMID:39115062
A guide to selecting high-performing antibodies for human Midkine for use in Western blot and immunoprecipitation., PMID:39092005
High Body Mass Index and Response to Anti-Tumor Necrosis Factor Therapy in Pediatric Crohn's Disease., PMID:38445644
A mechanistically novel peptide agonist of the IL-7 receptor that addresses limitations of IL-7 cytokine therapy., PMID:37874823
Systematic review and meta-analysis of the factors affecting waning of post-vaccination neutralizing antibody responses against SARS-CoV-2., PMID:37863890
Integrated single-cell and spatial transcriptomics reveals heterogeneity of fibroblast and pivotal genes in psoriasis., PMID:37816883
Desensitization and remission after peanut sublingual immunotherapy in 1- to 4-year-old peanut-allergic children: A randomized, placebo-controlled trial., PMID:37815782
Insight into the mechanism of CD34+ cell mobilisation impairment in multiple myeloma patients treated with anti-CD38 therapy., PMID:37807708
Worldwide Index of Serotype-Specific Pneumococcal Antibody Responses (WISSPAR): A curated database of clinical trial data., PMID:37564746
Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Antibody Responses After Community Infections in Children and Adults., PMID:37213425
Comparative Effectiveness of Anti-TNF in Combination With Low-Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn's Disease: A Pragmatic Randomized Trial., PMID:37004887
Open-label study of the efficacy, safety, and durability of peanut sublingual immunotherapy in peanut-allergic children., PMID:36828080
Phase 2 study of anti-disialoganglioside antibody, dinutuximab, in combination with GM-CSF in patients with recurrent osteosarcoma: A report from the Children's Oncology Group., PMID:35809374
Kinetics of basophil hyporesponsiveness during short-course peanut oral immunotherapy., PMID:35716952
CAF-derived midkine promotes EMT and cisplatin resistance by upregulating lncRNA ST7-AS1 in gastric cancer., PMID:35588343
Spike-directed vaccination elicits robust spike-specific T-cell response, including to mutant strains., PMID:34483067
Vedolizumab Is Associated With a Lower Risk of Serious Infections Than Anti-Tumor Necrosis Factor Agents in Older Adults., PMID:34481954
Robust Antibody and T Cell Responses to SARS-CoV-2 in Patients with Antibody Deficiency., PMID:33983545
Prospective Quantification of CSF Biomarkers in Antibody-Mediated Encephalitis., PMID:33795390
Soluble Biomarkers for Prediction of Vascular and Gastrointestinal Disease Severity in Patients with Systemic Sclerosis., PMID:40270643
Proangiogenic factor midkine is increased in melanoma patients with sleep apnea and induces tumor cell proliferation., PMID:33058223
Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study., PMID:32719045
Catatonic features in children and adolescents with N-methyl-d-aspartate receptor antibody encephalitis., PMID:38424748
A novel proangiogenic B cell subset is increased in cancer and chronic inflammation., PMID:32426497
The CD151-midkine pathway regulates the immune microenvironment in inflammatory breast cancer., PMID:32129471
Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception., PMID:30907987
The effectiveness of serum midkine in detecting esophageal squamous cell carcinoma., PMID:30778774
Changes of serum midkine as a dynamic prognostic factor to monitor disease status in papillary thyroid cancer., PMID:30200153
Influence of Menopause on Inflammatory Cytokines during Murine and Human Bone Fracture Healing., PMID:30013010
Development of bead based multiplexed immunoassay for evaluation of midkine, syndecan-1, and ANGPTL4 in patient serum., PMID:29309212
The inflammatory phase of fracture healing is influenced by oestrogen status in mice., PMID:28683813
Inhibition of Midkine Augments Osteoporotic Fracture Healing., PMID:27410432
Antagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callus., PMID:27111560
Identification of novel therapeutic targets in the secretome of ionizing radiation‑induced senescent tumor cells., PMID:26717900
Formation of vascular network structures within cardiac cell sheets from mouse embryonic stem cells., PMID:31245454
The Temporal Risk of Heart Failure Associated With Adjuvant Trastuzumab in Breast Cancer Patients: A Population Study., PMID:26476433
Oncogenic HER2 fusions in gastric cancer., PMID:25889497
Serum levels for midkine, a heparin-binding growth factor, inversely correlate with angiotensin and endothelin receptor autoantibody titers in patients with macroangiopathy., PMID:25056169
PKCδ/midkine pathway drives hypoxia-induced proliferation and differentiation of human lung epithelial cells., PMID:24500281
The differential impact of coadministered vaccines, geographic region, vaccine product and other covariates on pneumococcal conjugate vaccine immunogenicity., PMID:24336055
Systematic review of the effect of pneumococcal conjugate vaccine dosing schedules on immunogenicity., PMID:24336054
In vivo growth of mantle cell lymphoma xenografts in immunodeficient mice is positively regulated by VEGF and associated with significant up-regulation of CD31/PECAM1., PMID:23537525
Deficiency of growth factor midkine exacerbates necrotizing glomerular injuries in progressive glomerulonephritis., PMID:23201132
For research use only. Not for human or drug use.
