Anti-Human LEP/Leptin Antibody (SAA1775)

Catalog No.

RHE29401

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

OBS, OB, Obese protein, LEP, Leptin, Obesity factor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P41159

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1775

One-year metreleptin in Colombian sisters with congenital leptin deficiency., PMID:40415699

Single-Cell RNA Sequencing Reveals Macrophage Dynamics During MASH in Leptin-Deficient Rats., PMID:39851524

Study of the relationship between thyroid autoimmunity, obesity and serum leptin level in a sample of Egyptian individuals., PMID:39427241

Leptin/Ghrelin Axis and Antibodies Reactive to Both Hormones in Relation to Metabolic Syndrome Components in Mexican Children., PMID:39133224

The influence of nutritional status, lipid profile, leptin concentration and polymorphism of genes encoding leptin and neuropeptide Y on the effectiveness of immunotherapy in advanced NSCLC patients., PMID:39090596

Subcutaneous panniculitis-like T-cell lymphoma and lupus erythematosus profundus: a diagnostic dilemma., PMID:38925673

Pembrolizumab for advanced urothelial carcinoma: exploratory ctDNA biomarker analyses of the KEYNOTE-361 phase 3 trial., PMID:38823511

Leptospira infection and carrier survey on rats from wet market areas in Kuala Lumpur, Malaysia., PMID:38648405

N-glycosylation of the SARS-CoV-2 spike protein at Asn331 and Asn343 is involved in spike-ACE2 binding, virus entry, and regulation of IL-6., PMID:38444370

Clinical Relevance of Lepidoglyphus destructor Sensitisation in Allergic Rhinitis: Nasal Provocation Test as in vivo Assessment., PMID:38266498

Multiple-Pathway Synergy Alters Steroidogenesis and Spermatogenesis in Response to an Immunocastration Vaccine in Goat., PMID:38201210

Lupus panniculitis as the initial presentation of systemic lupus erythematosus triggered by COVID-19 infection: case report and literature review., PMID:38033407

Leptin favors imbalance of antigen-specific CD4+ T-cells associated with severity of cat allergy., PMID:37954580

Obesity Contributes to Transformation of Myometrial Stem-Cell Niche to Leiomyoma via Inducing Oxidative Stress, DNA Damage, Proliferation, and Extracellular Matrix Deposition., PMID:37628676

Safety and immunogenicity of homologous versus heterologous booster dose with AZD1222, mRNA-1273, or MVC-COV1901 SARS-CoV-2 vaccines in adults: An observer-blinded, multi-center, phase 2 randomized trial., PMID:37080829

Seroprevalence of viral and bacterial pathogens among malaria patients in an endemic area of southern Venezuela., PMID:37038195

Panoramic view of clinical features of lupus erythematosus: a cross-sectional multicentre study from China., PMID:36941021

A National Multicenter Study of Leptin and Leptin Receptor Deficiency and Systematic Review., PMID:36825860

Bioinformatics methods in biomarkers of preeclampsia and associated potential drug applications., PMID:36258174

Centrifugal lipodystrophy on a spectrum with lupus erythematosus panniculitis in children and efficacy and safety of hydroxychloroquine: A clinicopathological study., PMID:36100983

Dupilumab modulates specific IgE mite responses at the molecular level in severe T2-high atopic dermatitis: A real-world experience., PMID:36035412

Storage Mite Precision Allergy Molecular Diagnosis in the Moderate-to-Severe T2-High Asthma Phenotype., PMID:35457116

Association of Leptin Receptor Q223R Gene Polymorphism and Breast Cancer Patients: A Case Control Study., PMID:35092386

Placental expression of endoglin, placental growth factor, leptin, and hypoxia-inducible factor-1 in diabetic pregnancy and pre-eclampsia., PMID:34937509

Adjuvant Effect of Orally Applied Preparations Containing Non-Digestible Polysaccharides on Influenza Vaccination in Healthy Seniors: A Double-Blind, Randomised, Controlled Pilot Trial., PMID:34444843

Circulating Mir-140 and leptin improve the accuracy of the differential diagnosis between psoriatic arthritis and rheumatoid arthritis: a case-control study., PMID:34380068

Analysis of Results of Specific IgE in 100 Atopic Dermatitis Patients with the Use of Multiplex Examination ALEX2-Allergy Explorer., PMID:34067936

Impairment of testes development in Yangzhou ganders by augmentation of leptin receptor signaling., PMID:34051590

Leptin Deficiency, Caused by Malnutrition, Makes You Susceptible to SARS-CoV-2 Infection but Could Offer Protection from Severe COVID-19., PMID:33980671

Serologic Survey of Selected Pathogens in Free-Ranging Bengal Tigers (Panthera tigris tigris) in Nepal., PMID:33822151

Evaluation of the Influence of Adalimumab on the Expression Profile of Leptin-Related Genes and Proteins in Keratinocytes Treated with Lipopolysaccharide A., PMID:33562571

Association of anticardiolipin antibodies, complement and leptin with the severity of coronary artery disease expressed as syntax score., PMID:33077690

Multiplex secretome engineering enhances recombinant protein production and purity., PMID:32313013

Successful treatment of refractory lupus erythematosus profundus with the interleukin-6 antagonist tocilizumab: a case report., PMID:32192399

Treatment of Childhood-Onset Lupus Erythematosus Panniculitis With Rituximab., PMID:32049306

A novel ELISA for quantification of glycoprotein in human rabies vaccines using a clinically proven virus neutralizing human monoclonal antibody., PMID:31971485

High-throughput transcriptional profiling combined with angiogenesis antibody array analysis in an orbital venous malformation cohort., PMID:31926133

A phase 1 antigen dose escalation trial to evaluate safety, tolerability and immunogenicity of the leprosy vaccine candidate LepVax (LEP-F1 + GLA-SE) in healthy adults., PMID:31899025

Use of Monocyte-Derived Macrophage Culture Increases Zika Virus Isolation Rate from Human Plasma., PMID:31739467

Analysis of Transcriptome, Selected Intracellular Signaling Pathways, Proliferation and Apoptosis of LNCaP Cells Exposed to High Leptin Concentrations., PMID:31671654

Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation., PMID:31434105

Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR., PMID:30958852

The influence of adalimumab on the expression profile of mRNAs and miRNAs related to the IL-12 and IL-23 signal paths., PMID:30707475

Seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, Malaysia: a cross sectional study., PMID:30428852

The potential anti-inflammatory role of adiponectin in food allergy: a case-control study on children., PMID:30401008

Effect of HTST and Holder Pasteurization on the Concentration of Immunoglobulins, Growth Factors, and Hormones in Donor Human Milk., PMID:30319659

Leptin Elicits LTC4 Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD2 Receptors., PMID:30298073

Antibody-mediated oral delivery of therapeutic DNA for type 2 diabetes mellitus., PMID:30065848

Combining 2-DE immunoblots and mass spectrometry to identify putative soybean (Glycine max) allergens., PMID:29673863

Influence of adipocyte size and adipose depot on the number of adipose tissue macrophages and the expression of adipokines in dairy cows at the end of pregnancy., PMID:29627241

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