Catalog No.
RHK28101
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
INDOL1, Indoleamine 2,3-dioxygenase-like protein 1, IDO2, IDO-2, Indoleamine-pyrrole 2,3-dioxygenase-like protein 1, Indoleamine 2,3-dioxygenase 2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q6ZQW0
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1774
Epacadostat Overcomes Cetuximab Resistance in Colorectal Cancer by Targeting IDO-Mediated Tryptophan Metabolism., PMID:40103010
Beyond CTLA-4 and PD-1 Inhibition: Novel Immune Checkpoint Molecules for Melanoma Treatment., PMID:37345056
The role of indoleamine 2,3-dioxygenase 1 in early-onset post-stroke depression., PMID:36911716
Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS)., PMID:36389710
A novel 10-gene immune-related lncRNA signature model for the prognosis of colorectal cancer., PMID:34814366
Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses., PMID:32973768
B-Cell-Targeted 3DNA Nanotherapy Against Indoleamine 2,3-Dioxygenase 2 (IDO2) Ameliorates Autoimmune Arthritis in a Preclinical Model., PMID:32924009
HIV-1 Tat - TLR4/MD2 interaction drives the expression of IDO-1 in monocytes derived dendritic cells through NF-κB dependent pathway., PMID:32424165
Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells., PMID:32384638
IDO Targeting in Sarcoma: Biological and Clinical Implications., PMID:32194552
Limited Effect of Indolamine 2,3-Dioxygenase Expression and Enzymatic Activity on Lupus-Like Disease in B6.Nba2 Mice., PMID:31555267
Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond., PMID:30203227
Therapeutic antibody targeting of indoleamine-2,3-dioxygenase (IDO2) inhibits autoimmune arthritis., PMID:28223071
IDO2 is a critical mediator of autoantibody production and inflammatory pathogenesis in a mouse model of autoimmune arthritis., PMID:24489090
The JAK inhibitor, tofacitinib, reduces the T cell stimulatory capacity of human monocyte-derived dendritic cells., PMID:24013646
Suppression of acute graft-versus-host response by TCDD is independent of the CTLA-4-IFN-γ-IDO pathway., PMID:23798565
Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis., PMID:20181893
For research use only. Not for human or drug use.
