Catalog No.
RHK86301
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Meflin, Mesenchymal stromal cell-and fibroblast-expressing Linx paralogue
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
A0A146E5L3
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1762
Meflin/ISLR is a marker of adipose stem and progenitor cells in mice and humans that suppresses white adipose tissue remodeling and fibrosis., PMID:39136356
Synthetic retinoid-mediated preconditioning of cancer-associated fibroblasts and macrophages improves cancer response to immune checkpoint blockade., PMID:38849479
Good and Bad Stroma in Pancreatic Cancer: Relevance of Functional States of Cancer-Associated Fibroblasts., PMID:35884375
Safety and efficacy of MIKE-1 in patients with advanced pancreatic cancer: a study protocol for an open-label phase I/II investigator-initiated clinical trial based on a drug repositioning approach that reprograms the tumour stroma., PMID:35209871
Matrix remodeling-associated protein 8 is a marker of a subset of cancer-associated fibroblasts in pancreatic cancer., PMID:35020975
Meflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity., PMID:33960573
Generation and characterization of a Meflin-CreERT2 transgenic line for lineage tracing in white adipose tissue., PMID:33760832
Connective tissue growth factor produced by cancer‑associated fibroblasts correlates with poor prognosis in epithelioid malignant pleural mesothelioma., PMID:32705221
Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis., PMID:31439548
Roles of the Mesenchymal Stromal/Stem Cell Marker Meflin in Cardiac Tissue Repair and the Development of Diastolic Dysfunction., PMID:31221024
Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells., PMID:26924503