Catalog No.
RHK86101
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Nesfatin 1, NUCB2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
A0A097EV82
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1759
"Satiety molecules" - nesfatin-1 and glucagon-like peptide 1 in blood serum in patients with anorexia nervosa and obesity., PMID:40331844
Antidepressant and anxiolytic effects of Wuling Capsule in CSDS mice: Alleviating HPA axis hyperactivity via the Nesfatin-1/NF-κB signaling pathway., PMID:39551280
Immunohistochemical determination of the excitatory and inhibitory axonal endings contacting NUCB2/nesfatin-1 neurons., PMID:38157780
Chemogenetic activation of endogenous arginine vasopressin exerts anorexigenic effects via central nesfatin-1/NucB2 pathway., PMID:34134629
Reduction in Nesfatin-1 Levels in the Cerebrospinal Fluid and Increased Nigrostriatal Degeneration Following Ventricular Administration of Anti-nesfatin-1 Antibody in Mice., PMID:33613183
Central blockage of nesfatin-1 has anxiolytic effects but does not prevent corticotropin-releasing factor-induced anxiety in male rats., PMID:32736706
Endogenous NUCB2/Nesfatin-1 Regulates Energy Homeostasis Under Physiological Conditions in Male Rats., PMID:32722818
Gastrointestinal peptides and nonalcoholic fatty liver disease., PMID:31815784
Nesfatin-1 and visfatin expression is associated with reduced atherosclerotic disease risk in patients with rheumatoid arthritis., PMID:29475075
The Inhibitory Effects of Nesfatin-1 in Ventromedial Hypothalamus on Gastric Function and Its Regulation by Nucleus Accumbens., PMID:28105016
Nesfatin-1 regulates the lateral hypothalamic area melanin-concentrating hormone-responsive gastric distension-sensitive neurons and gastric function via arcuate nucleus innervation., PMID:28081774
Nesfatin-1 influences the excitability of gastric distension-responsive neurons in the ventromedial hypothalamic nucleus of rats., PMID:27982684
The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) - 1, Nesfatin-1 and anthropometric features in patients with Hashimoto's thyroiditis: a randomized controlled trial., PMID:27852303
Nucleobindin 1 (NUCB1) is a Golgi-resident marker of neurons., PMID:26666627
Nesfatin-1 signaling in the basom edial amygdala modulates the gastric distension-sensitive neurons discharge and decreases gastric motility via melanocortin 3/4 receptors and modified by the arcuate nucleus., PMID:26144374
Nesfatin-1 Suppresses Cardiac L-type Ca²⁺ Channels Through Melanocortin Type 4 Receptor and the Novel Protein Kinase C Theta Isoform Pathway., PMID:25997563
The effects of nesfatin-1 in the paraventricular nucleus on gastric motility and its potential regulation by the lateral hypothalamic area in rats., PMID:25328037
Effects of exogenous nesfatin-1 on gastric distention-sensitive neurons in the central nucleus of the amygdala and gastric motility in rats., PMID:25220707
Expression of nucleobindin 1 (NUCB1) in pancreatic islets and other endocrine tissues., PMID:25038744
A role of nesfatin-1/NucB2 in dehydration-induced anorexia., PMID:24829503
Nesfatin-1/nucleobindin-2 like immunoreactivity in the olfactory system, brain and pituitary of frog, Microhyla ornata., PMID:24768694
Central nesfatin-1 influences the excitability of ghrelin-responsive gastric distension neurons in the arcuate nucleus and reduces gastric motility in rats., PMID:24289827
Role of nesfatin-1 in a rat model of visceral hypersensitivity., PMID:23801843
Nesfatin-1 inhibits ovarian epithelial carcinoma cell proliferation in vitro., PMID:23764403
Central and peripheral expression and distribution of NUCB2/nesfatin-1., PMID:23537079
Nesfatin-1, corticotropin-releasing hormone, thyrotropin-releasing hormone, and neuronal histamine interact in the hypothalamus to regulate feeding behavior., PMID:23106615
Restraint stress alters the secretory activity of neurons co-expressing urocortin-1, cocaine- and amphetamine-regulated transcript peptide and nesfatin-1 in the mouse Edinger-Westphal nucleus., PMID:20043894
Identification of nesfatin-1 as a satiety molecule in the hypothalamus., PMID:17036007
For research use only. Not for human or drug use.
