Catalog No.
RHJ82801
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
DICER, DICER1, Helicase MOI, Endoribonuclease Dicer, Helicase with RNase motif, HERNA, KIAA0928
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UPY3
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1726
Focal High-Grade Areas with a Tumor-in-Tumor Pattern: Another Feature of Pediatric DICER1-Associated Thyroid Carcinoma?, PMID:40448797
Exomic and epigenomic analysis of pulmonary blastoma., PMID:39121796
Histone H3 trimethylation on lysine 27 immunostaining pattern in DICER1-associated tumors., PMID:38715664
A comparative mRNA- and miRNA transcriptomics reveals novel molecular signatures associated with metastatic prostate cancers., PMID:36468011
Widespread formation of double-stranded RNAs in testis., PMID:34158368
Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma., PMID:34095712
MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis., PMID:33841401
Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells., PMID:33837743
Dicer increases the indication for trastuzumab treatment in gastric cancer patients via overexpression of human epidermal growth factor receptor 2., PMID:33772068
Evaluating genomic biomarkers associated with resistance or sensitivity to chemotherapy in patients with advanced breast and colorectal cancer., PMID:32847480
MicroRNA-425-5p Expression Affects BRAF/RAS/MAPK Pathways In Colorectal Cancers., PMID:31673240
Nuclear re-localization of Dicer in primary mouse embryonic fibroblast nuclei following DNA damage., PMID:29394246
Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration., PMID:29323137
Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects., PMID:29126434
Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity., PMID:27295554
Dicer expression in estrogen receptor-positive versus triple-negative breast cancer: an antibody comparison., PMID:27260947
Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression., PMID:26725326
Ablation of Dicer leads to widespread perturbation of signaling pathways., PMID:26032504
Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia., PMID:25405615
Downregulated expression of Dicer1 predicts inferior survival in primary gastrointestinal diffuse large B-cell lymphoma treated with CHOP-like regimen and rituximab., PMID:25195038
Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA., PMID:24814348
An immunohistochemical and molecular analysis of problematic and unclassified ovarian sex cord-stromal tumors., PMID:24134930
AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression., PMID:23811941
Expression of the RNase III enzyme DROSHA is reduced during progression of human cutaneous melanoma., PMID:23370771
Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients., PMID:23266047
Deregulated sex chromosome gene expression with male germ cell-specific loss of Dicer1., PMID:23056286
The RNase III enzyme Dicer is essential for germinal center B-cell formation., PMID:22117047
High expression of Dicer reveals a negative prognostic influence in certain subtypes of primary cutaneous T cell lymphomas., PMID:21937200
Functional dicer is necessary for appropriate specification of radial glia during early development of mouse telencephalon., PMID:21826226
Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas., PMID:21769619
Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers., PMID:21533284
Overexpression of Dicer predicts poor survival in colorectal cancer., PMID:21345667
Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs., PMID:21258322
MicroRNAs prevent the generation of autoreactive antibodies., PMID:21093320
Dicer is a key player in oocyte maturation., PMID:20827505
MicroRNAs are essential for the developmental switch from neurogenesis to gliogenesis in the developing spinal cord., PMID:20554876
Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway., PMID:19451544
Dicer is required for female reproductive tract development and fertility in the mouse., PMID:19197916
Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage., PMID:18329371
ATP modulates siRNA interactions with an endogenous human Dicer complex., PMID:16177131
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing., PMID:15713842
For research use only. Not for human or drug use.
