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Anti-Human DICER1 Antibody (SAA1726)

Catalog #:   RHJ82801 Specific References (41) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: Q9UPY3
Overview

Catalog No.

RHJ82801

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

DICER, DICER1, Helicase MOI, Endoribonuclease Dicer, Helicase with RNase motif, HERNA, KIAA0928

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UPY3

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1726

Data Image
References

Focal High-Grade Areas with a Tumor-in-Tumor Pattern: Another Feature of Pediatric DICER1-Associated Thyroid Carcinoma?, PMID:40448797

Exomic and epigenomic analysis of pulmonary blastoma., PMID:39121796

Histone H3 trimethylation on lysine 27 immunostaining pattern in DICER1-associated tumors., PMID:38715664

A comparative mRNA- and miRNA transcriptomics reveals novel molecular signatures associated with metastatic prostate cancers., PMID:36468011

Widespread formation of double-stranded RNAs in testis., PMID:34158368

Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma., PMID:34095712

MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis., PMID:33841401

Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells., PMID:33837743

Dicer increases the indication for trastuzumab treatment in gastric cancer patients via overexpression of human epidermal growth factor receptor 2., PMID:33772068

Evaluating genomic biomarkers associated with resistance or sensitivity to chemotherapy in patients with advanced breast and colorectal cancer., PMID:32847480

MicroRNA-425-5p Expression Affects BRAF/RAS/MAPK Pathways In Colorectal Cancers., PMID:31673240

Nuclear re-localization of Dicer in primary mouse embryonic fibroblast nuclei following DNA damage., PMID:29394246

Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration., PMID:29323137

Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects., PMID:29126434

Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity., PMID:27295554

Dicer expression in estrogen receptor-positive versus triple-negative breast cancer: an antibody comparison., PMID:27260947

Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression., PMID:26725326

Ablation of Dicer leads to widespread perturbation of signaling pathways., PMID:26032504

Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia., PMID:25405615

Downregulated expression of Dicer1 predicts inferior survival in primary gastrointestinal diffuse large B-cell lymphoma treated with CHOP-like regimen and rituximab., PMID:25195038

Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA., PMID:24814348

An immunohistochemical and molecular analysis of problematic and unclassified ovarian sex cord-stromal tumors., PMID:24134930

AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression., PMID:23811941

Expression of the RNase III enzyme DROSHA is reduced during progression of human cutaneous melanoma., PMID:23370771

Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients., PMID:23266047

Deregulated sex chromosome gene expression with male germ cell-specific loss of Dicer1., PMID:23056286

The RNase III enzyme Dicer is essential for germinal center B-cell formation., PMID:22117047

High expression of Dicer reveals a negative prognostic influence in certain subtypes of primary cutaneous T cell lymphomas., PMID:21937200

Functional dicer is necessary for appropriate specification of radial glia during early development of mouse telencephalon., PMID:21826226

Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas., PMID:21769619

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers., PMID:21533284

Overexpression of Dicer predicts poor survival in colorectal cancer., PMID:21345667

Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs., PMID:21258322

MicroRNAs prevent the generation of autoreactive antibodies., PMID:21093320

Dicer is a key player in oocyte maturation., PMID:20827505

MicroRNAs are essential for the developmental switch from neurogenesis to gliogenesis in the developing spinal cord., PMID:20554876

Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway., PMID:19451544

Dicer is required for female reproductive tract development and fertility in the mouse., PMID:19197916

Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage., PMID:18329371

ATP modulates siRNA interactions with an endogenous human Dicer complex., PMID:16177131

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing., PMID:15713842

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Human DICER1 Antibody (SAA1726) [RHJ82801]
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