Anti-Human ADAM28 Antibody (SAA1723)

Catalog No.

RHJ79001

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

MDCL, MDC-L, Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L, ADAM 28, ADAM28, eMDC II, ADAM23, Disintegrin and metalloproteinase domain-containing protein 28

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UKQ2

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1723

Selective Inhibition of ADAM28 Suppresses Lung Carcinoma Cell Growth and Metastasis., PMID:30190423

Characterization of CD200 Ectodomain Shedding., PMID:27111430

ADAM28 is expressed by epithelial cells in human normal tissues and protects from C1q-induced cell death., PMID:26918856

Src plays a key role in ADAM28 expression in v-src-transformed epithelial cells and human carcinoma cells., PMID:24007880

Effect of ADAM28 on carcinoma cell metastasis by cleavage of von Willebrand factor., PMID:22636800

Modulation of integrin α4β1 by ADAM28 promotes lymphocyte adhesion and transendothelial migration., PMID:21332445

Essential role of ADAM28 in regulating the proliferation and differentiation of human dental papilla mesenchymal cells (hDPMCs)., PMID:18690470

ADAM28 is overexpressed in human breast carcinomas: implications for carcinoma cell proliferation through cleavage of insulin-like growth factor binding protein-3., PMID:17047053

ADAM28 participates in the regulation of tooth development., PMID:16836973

ADAM disintegrin-like domain recognition by the lymphocyte integrins alpha4beta1 and alpha4beta7., PMID:15504110

Integrin alpha4beta1-dependent adhesion to ADAM 28 (MDC-L) requires an extended surface of the disintegrin domain., PMID:12667064

The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1., PMID:11724793

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Anti-Human ADAM28 Antibody (SAA1723).pdf