Catalog No.
RHJ39901
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
LIG-1, Leucine-rich repeats and immunoglobulin-like domains protein 1, LIG1, LRIG1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q96JA1
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1709
Lrig1-expression confers suppressive function to CD4+ cells and is essential for averting autoimmunity via the Smad2/3/Foxp3 axis., PMID:37666819
A member of the immunoglobulin superfamily lrig-1 might be involved in the immune priming of Scylla paramamosain in response to the infection and re-infection by Vibrio parahaemolyticus., PMID:37302729
miR-301a-3p induced by endoplasmic reticulum stress mediates the occurrence and transmission of trastuzumab resistance in HER2-positive gastric cancer., PMID:34257270
Leucine-rich Repeats and Immunoglobulin 1 (LRIG1) Ameliorates Liver Fibrosis and Hepatic Stellate Cell Activation via Inhibiting Sphingosine Kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P) Pathway., PMID:33463106
Novel Somatic Genetic Variants as Predictors of Resistance to EGFR-Targeted Therapies in Metastatic Colorectal Cancer Patients., PMID:32796636
Pigment epithelium-derived factor peptide reverses mouse age-related meibomian gland atrophy., PMID:31129251
LRIG1‑2 and LMO7 immunoreactivity in vulvar squamous cell carcinoma: Association with prognosis in relation to HPV‑DNA and p16INK4a status., PMID:31059071
Glucocorticoid Receptor Modulates EGFR Feedback upon Acquisition of Resistance to Monoclonal Antibodies., PMID:31052457
Lrig1 Expression in Human Sebaceous Gland Tumors., PMID:27504445
Immunofluorescence Tomography of Mouse Ocular Surface Epithelial Stem Cells and Their Niche Microenvironment., PMID:26559480
LRIG1 Regulates Ontogeny of Smooth Muscle-Derived Subsets of Interstitial Cells of Cajal in Mice., PMID:25921371
Construction of human LRIG1-TAT fusions and TAT-mediated LRIG1 protein delivery., PMID:25661388
Using a new Lrig1 reporter mouse to assess differences between two Lrig1 antibodies in the intestine., PMID:25460603
USP8 modulates ubiquitination of LRIG1 for Met degradation., PMID:24828152
Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody., PMID:23208509
Paneth cells in intestinal homeostasis and tissue injury., PMID:22745693
Stem cell dynamics in sebaceous gland morphogenesis in mouse skin., PMID:22227295
LRIG1 protein in human cells and tissues., PMID:12684867
For research use only. Not for human or drug use.
