Catalog No.
RHJ22401
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
PGSF2, Immunoglobulin superfamily member 1, Inhibin-binding protein, Pituitary gland-specific factor 2, IGSF1, p120, IGDC1, KIAA0364, Immunoglobulin-like domain-containing protein 1, IgSF1, InhBP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8N6C5
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1704
A proteomic atlas of glypican-3 interacting partners: Identification of alpha-fetoprotein and other extracellular proteins as potential immunotherapy targets in liver cancer., PMID:39822733
Clinical and molecular analyses of isolated central congenital hypothyroidism based on a survey conducted in Japan., PMID:38462462
Congenital Central Hypothyroidism Caused by Novel Variants in IGSF1 Gene: Case Series of 3 Patients., PMID:38295770
The Immune Suppressor IGSF1 as a Potential Target for Cancer Immunotherapy., PMID:38289363
Hepatomegaly and fatty liver disease secondary to central hypothyroidism in combination with macrosomia as initial presentation of IGSF1 deficiency syndrome., PMID:37493943
[Clinical characteristics and genetic analysis of four patients with central hypothyroidism due to IGSF1 gene variants]., PMID:36854408
IGSF1 mutation as a cause of isolated central hypothyroidism., PMID:36464600
Integrated analysis identifies the IL6/JAK/STAT signaling pathway and the estrogen response pathway associated with the pathogenesis of intracranial aneurysms., PMID:36451838
IGSF1 mutations are the most frequent genetic aetiology of thyrotropin deficiency., PMID:36201163
Whole-genome sequencing identifies new candidate genes for nonobstructive azoospermia., PMID:36017582
IGSF1 Deficiency Leads to Reduced TSH Production Independent of Alterations in Thyroid Hormone Action in Male Mice., PMID:35708735
The extant immunoglobulin superfamily, member 1 gene results from an ancestral gene duplication in eutherian mammals., PMID:35653309
A Novel Pathogenic IGSF1 Variant in a Patient with GH and TSH Deficiency Diagnosed by High IGF-I Values at Transition to Adult Care., PMID:35466665
Case Report: A Detailed Phenotypic Description of Patients and Relatives with Combined Central Hypothyroidism and Growth Hormone Deficiency Carrying IGSF1 Mutations., PMID:35456429
Congenital Central Hypothyroidism Caused by a Novel IGSF1 Variant Identified in a French Family., PMID:35350016
Identification of novel prostate cancer genes in patients stratified by Gleason classification: Role of antitumoral genes., PMID:35234293
Diagnosis and Management of Central Congenital Hypothyroidism., PMID:34566885
Congenital isolated central hypothyroidism: Novel mutations and their functional implications., PMID:34225927
Estimating the accuracy of pharmacophore-based detection of cognate receptor-ligand pairs in the immunoglobulin superfamily., PMID:33483991
The IGSF1 Deficiency Syndrome May Present with Normal Free T4 Levels, Severe Obesity, or Premature Testicular Growth., PMID:33045800
A Case of Congenital Central Hypothyroidism Caused by a Novel Variant (Gln1255Ter) in IGSF1 Gene., PMID:32772515
Letter to the Editor: "IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction"., PMID:32211782
Response to Letter to the Editor: "IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction"., PMID:32211768
IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction., PMID:31650157
A Tale of Two Proteins: Betaglycan, IGSF1, and the Continuing Search for the Inhibin B Receptor., PMID:31648935
Genetics of Congenital Isolated TSH Deficiency: Mutation Screening of the Known Causative Genes and a Literature Review., PMID:31504637
Hypoprolactinemia as a Clue to Diagnosis of Mild Central Hypothyroidism due to IGSF1 Deficiency., PMID:31448769
IGSF1: A novel oncogene regulates the thyroid cancer progression., PMID:31343762
New genetic findings in a large cohort of congenital hypogonadotropic hypogonadism., PMID:31200363
Unraveling the LRC Evolution in Mammals: IGSF1 and A1BG Provide the Keys., PMID:31106814
Age-related gene and miRNA expression changes in airways of healthy individuals., PMID:30842487
A novel IGSF1 mutation in a large Irish kindred highlights the need for familial screening in the IGSF1 deficiency syndrome., PMID:30086211
Regulation and mechanism of miR-146 on renal ischemia reperfusion injury., PMID:29441948
A Japanese patient with congenital central hypothyroidism caused by a novel IGSF1 mutation., PMID:29425110
The short mRNA isoform of the immunoglobulin superfamily, member 1 gene encodes an intracellular glycoprotein., PMID:28686733
TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice., PMID:28324000
The syndrome of central hypothyroidism and macroorchidism: IGSF1 controls TRHR and FSHB expression by differential modulation of pituitary TGFβ and Activin pathways., PMID:28262687
A Japanese Family with Central Hypothyroidism Caused by a Novel IGSF1 Mutation., PMID:27762734
Familial Central Hypothyroidism Caused by a Novel IGSF1 Gene Mutation., PMID:27310681
Identification of an IGSF1-specific deletion in a five-generation pedigree with X-linked Central Hypothyroidism without macroorchidism., PMID:27146357
IGSF1 Deficiency: Lessons From an Extensive Case Series and Recommendations for Clinical Management., PMID:26840047
Mild deficits in attentional control in patients with the IGSF1 deficiency syndrome., PMID:26387489
Pituitary Hormone Secretion Profiles in IGSF1 Deficiency Syndrome., PMID:26336917
Combined Growth Hormone and Thyroid-Stimulating Hormone Deficiency in a Japanese Patient with a Novel Frameshift Mutation in IGSF1., PMID:26302767
Rare coding variants and X-linked loci associated with age at menarche., PMID:26239645
Spatial and temporal expression of immunoglobulin superfamily member 1 in the rat., PMID:26163525
Is IGSF1 involved in human pituitary tumor formation?, PMID:25527509
IGSF1 variants in boys with familial delayed puberty., PMID:25354429
The IGSF1 deficiency syndrome: characteristics of male and female patients., PMID:24108313
Three novel IGSF1 mutations in four Japanese patients with X-linked congenital central hypothyroidism., PMID:23966245
For research use only. Not for human or drug use.
