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Anti-Human SLC30A8 Antibody (SAA1702)

Catalog #:   RHJ18801 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: Q8IWU4
Overview

Catalog No.

RHJ18801

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

ZNT8, SLC30A8, Zinc transporter 8, ZnT-8, Solute carrier family 30 member 8

Concentration

2.31 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8IWU4

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1702

Data Image
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Islet autoantibodies in Thai individuals diagnosed with type 1 diabetes before 30 years of age: a large multicentre nationwide study., PMID:39971754

Characterisation of islet antibody-negative type 1 diabetes mellitus in Indian children., PMID:39556519

Estimation of Individual Positive Anti-Islet Autoantibodies from 3 Screen ICA Titer., PMID:39062856

Islet autoantibody frequency in relatives of children with type 1 diabetes who have a type 2 diabetes diagnosis., PMID:38937948

Childhood screening for type 1 diabetes comparing automated multiplex Antibody Detection by Agglutination-PCR (ADAP) with single plex islet autoantibody radiobinding assays., PMID:38723553

Prevalence, diagnostic utility, and clinical characteristics of ZnT8 antibody in children with type 1 diabetes in Northern Taiwan., PMID:38267283

Study of the diagnostic efficiency of anti-ZnT8 autoantibodies for type 1 diabetes in pediatric patients., PMID:37658812

Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo β-Cell Imaging and Islet-Specific Therapies., PMID:36448936

Antigen-specific immunotherapies in type 1 diabetes., PMID:35868165

Autoantibodies to Zinc Transporter 8 and SLC30A8 Genotype in Type 1 Diabetes Childhood: A Pioneering Study in North Africa., PMID:35656360

The common rs13266634 C > T variant in SLC30A8 contributes to the heterogeneity of phenotype and clinical features of both type 1 and type 2 diabetic subtypes., PMID:35034185

Evaluation of the Diagnostic and Predictive Value of Glutamic Acid Decarboxylase, Zinc Transporter 8 Serum Levels in Alzheimer's Disease., PMID:35023669

Genetic variation at ERBB3/IKZF4 and sexual dimorphism in epitope spreading in single autoantibody-positive relatives., PMID:34448034

The Unfavorable Impact of DR9/DR9 Genotype on the Frequency and Quality of Partial Remission in Type 1 Diabetes., PMID:34390338

Simplifying prediction of disease progression in pre-symptomatic type 1 diabetes using a single blood sample., PMID:34338806

Zinc transporter 8 (ZnT8) autoantibody prevalence in black South African participants with type 1 diabetes., PMID:34271898

Novel autoantibodies to the β-cell surface epitopes of ZnT8 in patients progressing to type-1 diabetes., PMID:34130115

Genetic Composition and Autoantibody Titers Model the Probability of Detecting C-Peptide Following Type 1 Diabetes Diagnosis., PMID:33419759

Prevalence of Zinc Transporter 8 Auto Antibodies among Newly Diagnosed Type 1 Diabetic Cases Admitted to Assiut University Children Hospital., PMID:33180385

Islet autoantibody profiles associated with higher diabetes risk in Lithuanian compared with English schoolchildren., PMID:32979862

Autoantibodies against zinc transporter 8 further stratify the autoantibody-defined risk for type 1 diabetes in a general population of schoolchildren and have distinctive isoform binding patterns in different forms of autoimmune diabetes: results from the Karlsburg Type 1 Diabetes Risk Study., PMID:32799407

Type 1 diabetes in Africa: an immunogenetic study in the Amhara of North-West Ethiopia., PMID:32705316

Different interaction of onset age and duration of type 1 diabetes on the dynamics of autoantibodies to insulinoma-associated antigen-2 and zinc transporter 8., PMID:32696593

Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes., PMID:32634859

Association of diabetes-related autoantibodies with the incidence of asthma, eczema and allergic rhinitis in the TRIGR randomised clinical trial., PMID:32548702

Why is the presence of autoantibodies against GAD associated with a relatively slow progression to clinical diabetes?, PMID:32451571

Organ-specific autoantibodies in Chinese patients newly diagnosed with type 1 diabetes mellitus., PMID:32295990

Zinc transporter 8 autoantibodies complement glutamic acid decarboxylase and insulinoma-associated antigen-2 autoantibodies in the identification and characterization of Japanese type 1 diabetes., PMID:32175683

Older age of childhood type 1 diabetes onset is associated with islet autoantibody positivity >30 years later: the Pittsburgh Epidemiology of Diabetes Complications Study., PMID:32011014

Low prevalence of maternal microchimerism in peripheral blood of Japanese children with type 1 diabetes., PMID:31872455

What has zinc transporter 8 autoimmunity taught us about type 1 diabetes?, PMID:31444530

Analysis of diabetes-associated autoantibodies in children and adolescents with autoimmune thyroid diseases., PMID:30903759

In silico identification and wet lab validation of novel cryptic B cell epitopes in ZnT8 zinc transporter autoantigen., PMID:30710592

Childhood thyroid autoimmunity and relation to islet autoantibodies in children at risk for type 1 diabetes in the diabetes prediction in skåne (DiPiS) study., PMID:30486698

Identification of autoimmune type 1 diabetes and multiple organ-specific autoantibodies in adult-onset non-insulin-requiring diabetes in China: A population-based multicentre nationwide survey., PMID:30471182

Autoantibodies against ZnT8 are rare in Central-European LADA patients and absent in MODY patients, including those positive for other autoantibodies., PMID:30377089

Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8., PMID:30181214

Prevalence of islet autoantibodies in Thai juvenile-onset type 1 diabetes., PMID:30151912

Could ZnT8 antibodies replace ICA, GAD, IA2 and insulin antibodies in the diagnosis of type 1 diabetes?, PMID:29487039

Autoantibodies against zinc transporter 8 are related to age and metabolic state in patients with newly diagnosed autoimmune diabetes., PMID:29327148

Prevalence of ZnT8 Antibody in Turkish Children and Adolescents with New Onset Type 1 Diabetes., PMID:28943512

Detection of Islet Cell Immune Reactivity with Low Glycemic Index Foods: Is This a Concern for Type 1 Diabetes?, PMID:28819632

Twenty-Year Progression Rate to Clinical Onset According to Autoantibody Profile, Age, and HLA-DQ Genotype in a Registry-Based Group of Children and Adults With a First-Degree Relative With Type 1 Diabetes., PMID:28701370

Primary islet autoantibody at initial seroconversion and autoantibodies at diagnosis of type 1 diabetes as markers of disease heterogeneity., PMID:28597949

Impact of Age and Antibody Type on Progression From Single to Multiple Autoantibodies in Type 1 Diabetes Relatives., PMID:28531305

Can Non-HLA Single Nucleotide Polymorphisms Help Stratify Risk in TrialNet Relatives at Risk for Type 1 Diabetes?, PMID:28520980

Importance of Zinc Transporter 8 Autoantibody in the Diagnosis of Type 1 Diabetes in Latin Americans., PMID:28303020

Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells., PMID:28130446

[Latent autoimmune diabetes of adults (LADA): The informative value of autoantibodies]., PMID:27801418

3 Screen islet cell autoantibody ELISA: A sensitive and specific ELISA for the combined measurement of autoantibodies to GAD65, to IA-2 and to ZnT8., PMID:27570064

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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For research use only. Not for human or drug use.

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Anti-Human SLC30A8 Antibody (SAA1702) [RHJ18801]
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