Catalog No.
RHJ09801
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Lipasin, C19orf80, ANGPTL8, RIFL, Refeeding-induced fat and liver protein, Angiopoietin-like protein 8, Betatrophin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q6UXH0
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1698
Angiopoietin-like protein inhibitors: Promising agents for the treatment of familial hypercholesterolemia and atherogenic dyslipidemia., PMID:40344904
Inhibition of the ANGPTL3/8 Complex for the Prevention and Treatment of Atherosclerotic Cardiovascular Disease., PMID:39565562
Angiopoietin-Like Proteins: Cardiovascular Biology and Therapeutic Targeting for the Prevention of Cardiovascular Diseases., PMID:37295611
An anti-ANGPTL3/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif., PMID:35307397
The Potential of ANGPTL8 Antagonism to Simultaneously Reduce Triglyceride and Increase HDL-Cholesterol Plasma Levels., PMID:34869703
Angiopoietin-like proteins 3, 4 and 8 are linked to cardiovascular function in naïve sub-clinical and overt hypothyroid patients receiving levothyroxine therapy., PMID:34739390
ANGPTL3 as therapeutic target., PMID:34581310
Angiopoietin-like proteins in atherosclerosis., PMID:34153276
The Angiopoietin-Like Protein 3 and 8 Complex Interacts with Lipoprotein Lipase and Induces LPL Cleavage., PMID:33656326
Angiopoietin-like proteins as therapeutic targets for cardiovascular disease: focus on lipid disorders., PMID:31856617
Decreased circulating levels of ANGPTL8 in Graves' disease patients., PMID:30900216
New insights into angiopoietin-like proteins in lipid metabolism and cardiovascular disease risk., PMID:30893111
Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia., PMID:29752428
Increased thermogenesis by a noncanonical pathway in ANGPTL3/8-deficient mice., PMID:29358393
Angiopoietin-like 3 in lipoprotein metabolism., PMID:28984319
A New Tactic for Label-Free Recognition of β-Trophin via Electrochemiluminescent Signalling on an AuNPs Supported Immuno-Interface., PMID:28894260
ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance., PMID:28413163
ANGPTL8 Blockade With a Monoclonal Antibody Promotes Triglyceride Clearance, Energy Expenditure, and Weight Loss in Mice., PMID:28204173
Circulating Betatrophin Is Increased in Patients with Overt and Subclinical Hypothyroidism., PMID:27213151
A lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase., PMID:26687026
For research use only. Not for human or drug use.
