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Anti-Human SEZ6 Antibody (SAA1693)

Catalog #:   RHH86501 Specific References (14) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: Q53EL9
Overview

Catalog No.

RHH86501

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

hSEZ-6, SEZ6, Seizure protein 6 homolog, SEZ-6

Concentration

1.07 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q53EL9

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1693

Data Image
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Soluble VCAM-1 may serve as a pharmacodynamic CSF marker to monitor BACE2 activity in non-human primates., PMID:40480341

Assessment of targets of antibody drug conjugates in SCLC., PMID:39748112

Detection of SEZ6, a therapeutic target, in medullary thyroid carcinoma., PMID:39324657

A Phase I First-in-Human Study of ABBV-011, a Seizure-Related Homolog Protein 6-Targeting Antibody-Drug Conjugate, in Patients with Small Cell Lung Cancer., PMID:39287821

Antibody-drug conjugates treatment of small cell lung cancer: advances in clinical research., PMID:39090431

Preclinical Characterization of Catabolic Pathways and Metabolism of ABBV-011, a Novel Calicheamicin-Based SEZ6-Targeting Antibody-Drug Conjugate., PMID:38050039

Unlocking New Horizons in Small-Cell Lung Cancer Treatment: The Onset of Antibody-Drug Conjugates., PMID:38001628

ABBV-011, A Novel, Calicheamicin-Based Antibody-Drug Conjugate, Targets SEZ6 to Eradicate Small Cell Lung Cancer Tumors., PMID:35642431

Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome., PMID:29716987

Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons., PMID:27716410

Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease., PMID:26950848

The distribution of the seizure-related gene 6 (Sez-6) protein during postnatal development of the mouse forebrain suggests multiple functions for this protein: an analysis using a new antibody., PMID:21334315

Seizure-related gene 6 (Sez-6) in amacrine cells of the rodent retina and the consequence of gene deletion., PMID:19662096

Cloning and characterization of seizure-related gene, SEZ-6., PMID:7488116

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human SEZ6 Antibody (SAA1693) [RHH86501]
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