Catalog No.
RHH50001
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
R-spondin-1, hRspo1, RSPO1, Roof plate-specific spondin-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q2MKA7
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1690
Correlation between intestinal stem cell niche changes and small bowel crypt failure in patients with treatment-naïve celiac disease., PMID:38427764
Large-scale isolation of functional dermal papilla cells using novel surface marker LEPTIN Receptor., PMID:35524584
Triple-Decker Sandwich Cultures of Intestinal Organoids for Long-Term Live Imaging, Uniform Perturbation, and Statistical Sampling., PMID:35030297
Establishment and Culture of Human Intestinal Organoids Derived from Adult Stem Cells., PMID:32940424
Understanding the regulatory mechanisms of endometrial cells on activities of endometrial mesenchymal stem-like cells during menstruation., PMID:32552749
Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs., PMID:32160239
Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling., PMID:31914456
Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization., PMID:29967265
Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations., PMID:29928673
Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling., PMID:29151594
PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling., PMID:28740264
Generation and characterization of monoclonal antibodies against human LGR6., PMID:28013222
Marker genes identify three somatic cell types in the fetal mouse ovary., PMID:25158167
Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5., PMID:23809763
R-spondin1 deficiency in mice improves glycaemic control in association with increased beta cell mass., PMID:21484214
R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway., PMID:20506554
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche., PMID:19398967
Tipping the balance: modulating the Wnt pathway for tissue repair., PMID:19187992
R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation., PMID:18384673
For research use only. Not for human or drug use.
