Anti-Human MEF2C Antibody (SAA1659)

Catalog No.

RHG08701

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

MEF2C, Myocyte-specific enhancer factor 2C, Myocyte enhancer factor 2C

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q06413

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1659

Integrative miRNA-mRNA profiling uncovers mechanisms of belimumab action in systemic lupus erythematosus., PMID:40160819

Single-Cell Transcriptomics Identifies Selective Lineage-Specific Regulation of Genes in Aortic Smooth Muscle Cells in Mice., PMID:39744838

METTL3 promotes microglial inflammation via MEF2C in spinal cord injury., PMID:38180567

Emerging role for thymic stromal lymphopoietin-responsive regulatory T cells in colorectal cancer progression in humans and mice., PMID:35584230

Discovery of Novel Circulating Immune Complexes in Lupus Nephritis Using Immunoproteomics., PMID:35419005

The Cell Adhesion Molecule L1 Interacts with Methyl CpG Binding Protein 2 via Its Intracellular Domain., PMID:35408913

Comparing the epigenetic landscape in myonuclei purified with a PCM1 antibody from a fast/glycolytic and a slow/oxidative muscle., PMID:34752468

MiR-96-5p Induced by Palmitic Acid Suppresses the Myogenic Differentiation of C2C12 Myoblasts by Targeting FHL1., PMID:33322515

Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma., PMID:33094287

Loss of Mef2D function enhances TLR induced IL-10 production in macrophages., PMID:32725155

Nerve impulse transmission pathway-focused genes expression analysis in patients with primary hypothyroidism and autoimmune thyroiditis., PMID:32597152

B Cell Development sans B Cell Receptor Responsiveness Due to Unfolded Protein Response-Triggered Mef2c Protein Degradation., PMID:30305329

Isolation, Characterization and Differentiation of Mouse Cardiac Progenitor Cells., PMID:30196409

Comparative analysis of histologically classified oligodendrogliomas reveals characteristic molecular differences between subgroups., PMID:29631562

Trichinella spiralis muscle larvae excretory-secretory products induce changes in cytoskeletal and myogenic transcription factors in primary myoblast cultures., PMID:29258830

Assessing Cardiomyocyte Subtypes Following Transcription Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts., PMID:28362413

High expression of myocyte enhancer factor 2C (MEF2C) is associated with adverse-risk features and poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group., PMID:26487643

Analysis of SOST expression using large minigenes reveals the MEF2C binding site in the evolutionarily conserved region (ECR5) enhancer mediates forskolin, but not 1,25-dihydroxyvitamin D3 or TGFβ1 responsiveness., PMID:26361013

Adipose-derived stem cell adhesion on laminin-coated microcarriers improves commitment toward the cardiomyogenic lineage., PMID:25098676

Islet-1 may function as an assistant factor for histone acetylation and regulation of cardiac development-related transcription factor Mef2c expression., PMID:24147056

HDAC inhibitor sodium butyrate augments the MEF2C enhancement of Nampt expression under hypoxia., PMID:23888946

Accelerated direct reprogramming of fibroblasts into cardiomyocyte-like cells with the MyoD transactivation domain., PMID:23794713

In vivo cardiac cellular reprogramming efficacy is enhanced by angiogenic preconditioning of the infarcted myocardium with vascular endothelial growth factor., PMID:23316332

Regulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostin., PMID:22927401

Myocardin-A enhances expression of promyogenic genes without depressing telomerase activity in adipose tissue-derived mesenchymal stem cells., PMID:22884695

Developmentally regulated expression of MEF2C limits the response to BCR engagement in transitional B cells., PMID:22311635

Potential characteristics of stem cells from human exfoliated deciduous teeth compared with bone marrow-derived mesenchymal stem cells for mineralized tissue-forming cell biology., PMID:22099898

HDAC inhibition promotes cardiogenesis and the survival of embryonic stem cells through proteasome-dependent pathway., PMID:21751234

Analysis of the chondrogenic potential and secretome of mesenchymal stem cells derived from human umbilical cord stroma., PMID:20977334

Sodium arsenite delays the differentiation of C2C12 mouse myoblast cells and alters methylation patterns on the transcription factor myogenin., PMID:20965206

Activity assays for extracellular signal-regulated kinase 5., PMID:20811978

A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression., PMID:20447394

The calcineurin-myocyte enhancer factor 2c pathway mediates cardiac hypertrophy induced by endoplasmic reticulum stress in neonatal rat cardiomyocytes., PMID:20207814

Co-culture with cardiomyocytes enhanced the myogenic conversion of mesenchymal stromal cells in a dose-dependent manner., PMID:20063193

Protection of retinal ganglion cells by caspase substrate-binding peptide IQACRG from N-methyl-D-aspartate receptor-mediated excitotoxicity., PMID:19815732

A p38 MAPK-MEF2C pathway regulates B-cell proliferation., PMID:18955699

Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation., PMID:18438409

Gene Ontology-driven transcriptional analysis of CD34+ cell-initiated megakaryocytic cultures identifies new transcriptional regulators of megakaryopoiesis., PMID:18252802

STAT3-dependent mouse embryonic stem cell differentiation into cardiomyocytes: analysis of molecular signaling and therapeutic efficacy of cardiomyocyte precommitted mES transplantation in a mouse model of myocardial infarction., PMID:17823373

Control of the SOST bone enhancer by PTH using MEF2 transcription factors., PMID:17696759

Differentiation in vivo of cardiac committed human embryonic stem cells in postmyocardial infarcted rats., PMID:17540853

Peroxisome proliferator-activated receptor alpha is involved in cardiomyocyte differentiation of murine embryonic stem cells in vitro., PMID:17467307

TACE release of TNF-alpha mediates mechanotransduction-induced activation of p38 MAPK and myogenesis., PMID:17264149

TNF-alpha regulates myogenesis and muscle regeneration by activating p38 MAPK., PMID:17151142

HDAC activity regulates entry of mesoderm cells into the cardiac muscle lineage., PMID:17038545

MEF2C DNA-binding activity is inhibited through its interaction with the regulatory protein Ki-1/57., PMID:15862299

Sequestration of pRb by cyclin D3 causes intranuclear reorganization of lamin A/C during muscle cell differentiation., PMID:15703219

Dual effects of the homeobox transcription factor Csx/Nkx2-5 on cardiomyocytes., PMID:12408979

The C-terminus of myogenin, but not MyoD, targets upregulation of MEF2C expression., PMID:12135755

Functional regulatory regions of human transcription factor MEF2C., PMID:11744164

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