Catalog No.
RHF94101
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Desmosomal glycoprotein II, Desmocollin-2, DSC2, DSC3, Cadherin family member 2, CDHF2, Desmosomal glycoprotein III, Desmocollin-3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q02487
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1658
Immunohistopathological analyses of a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3., PMID:39073162
Atypical pemphigus with anti-desmocollin 2 and 3 antibodies, initially presenting as pemphigus vulgaris with anti-desmoglein 3 antibodies., PMID:32808594
Paraneoplastic pemphigus associated with Waldenström's macroglobulinemia., PMID:32103535
The involvement of ADAM10 in acantholysis in mucocutaneous pemphigus vulgaris depends on the autoantibody profile of each patient., PMID:31370093
A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa., PMID:31281635
Pemphigus herpetiformis with autoantibodies to desmocollins 1, 2 and 3., PMID:29333762
Routine detection of serum antidesmocollin autoantibodies is only useful in patients with atypical pemphigus., PMID:28815795
Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase., PMID:28740231
Establishment of IgA ELISAs of mammalian recombinant proteins of human desmocollins 1-3., PMID:27150020
Oxidized low-density lipoprotein attenuated desmoglein 1 and desmocollin 2 expression via LOX-1/Ca(2+)/PKC-β signal in human umbilical vein endothelial cells., PMID:26498522
Detection of IgG antibodies to desmoglein 3 and desmocollins 2 and 3 in mucosal dominant-type pemphigus vulgaris with severe pharyngalgia and hyperemia of the bulbar conjunctiva., PMID:26463887
Clinical and immunological findings in 104 cases of paraneoplastic pemphigus., PMID:26358412
Anti-desmocollin autoantibodies in nonclassical pemphigus., PMID:25640111
Desmocollin-specific antibodies in a patient with Hailey-Hailey disease., PMID:25580559
Paraneoplastic pemphigus with eosinophilic spongiosis and autoantibodies against desmocollins 2 and 3., PMID:24635070
IgA/IgG pemphigus with infiltration of neutrophils and eosinophils in an ulcerative colitis patient., PMID:24604005
The expanding spectrum of IgA pemphigus: a case report and review of the literature., PMID:24601812
Desmosomal cadherins are decreased in explanted arrhythmogenic right ventricular dysplasia/cardiomyopathy patient hearts., PMID:24086444
Two cases of pemphigus vegetans with IgG anti-desmocollin 3 antibodies., PMID:23946009
IgA pemphigus with non-pustular erythematous lesions and IgA antibodies to desmocollins 1 and 2., PMID:23797684
Mesenchymal-epithelial transitions: spontaneous and cumulative syntheses of epithelial marker molecules and their assemblies to novel cell junctions connecting human hematopoietic tumor cells to carcinomatoid tissue structures., PMID:21647878
De novo desmin-mutation N116S is associated with arrhythmogenic right ventricular cardiomyopathy., PMID:20829228
Compound and digenic heterozygosity contributes to arrhythmogenic right ventricular cardiomyopathy., PMID:20152563
Autoantibodies against desmocollins in European patients with pemphigus., PMID:19456767
Desmoglein-2: a novel regulator of apoptosis in the intestinal epithelium., PMID:17804817
The area composita of adhering junctions connecting heart muscle cells of vertebrates - III: assembly and disintegration of intercalated disks in rat cardiomyocytes growing in culture., PMID:17275137
Desmosome-binding antibody KM48 recognises an extracellular antigen different from desmosomal cadherins Dsg 1-3 and Dsc 1-3., PMID:15757816
The detection of IgG and IgA autoantibodies to desmocollins 1-3 by enzyme-linked immunosorbent assays using baculovirus-expressed proteins, in atypical pemphigus but not in typical pemphigus., PMID:15270874
Molecular characterization of desmosomes in meningiomas and arachnoidal tissue., PMID:12845453
Comparative study of autoantigen profile between Colombian and Brazilian types of endemic pemphigus foliaceus by various biochemical and molecular biological techniques., PMID:12788527
Identification of desmoglein 1 as autoantigen in a patient with intraepidermal neutrophilic IgA dermatosis type of IgA pemphigus., PMID:10839721
Expression of a single pair of desmosomal glycoproteins renders the corneal epithelium unique amongst stratified epithelia., PMID:10634593
Diversity of desmosomal proteins in regenerating epidermis: immunohistochemical study using a human skin organ culture model., PMID:10482015
Compositionally different desmosomes in the various compartments of the human hair follicle., PMID:9810708
Antisense expression of a desmocollin gene in MDCK cells alters desmosome plaque assembly but does not affect desmoglein expression., PMID:9716266
Human desmocollin 1 (Dsc1) is an autoantigen for the subcorneal pustular dermatosis type of IgA pemphigus., PMID:9242496
The differential expression of desmocollin isoforms in mammary epithelia., PMID:8878890
Distinct desmocollin isoforms occur in the same desmosomes and show reciprocally graded distributions in bovine nasal epidermis., PMID:8755539
The desmocollins of human foreskin epidermis: identification and chromosomal assignment of a third gene and expression patterns of the three isoforms., PMID:7665906
A case of pemphigus vulgaris showing reactivity with pemphigus antigens (Dsg1 and Dsg3) and desmocollins., PMID:7706774
Unusual acantholytic bullous dermatosis associated with neoplasia and IgG and IgA antibodies against bovine desmocollins I and II., PMID:8034804
The bovine desmocollin family: a new gene and expression patterns reflecting epithelial cell proliferation and differentiation., PMID:8034749
Detection of anti-desmocollins I and II autoantibodies in two cases of Hallopeau type pemphigus vegetans by immunoblot analysis., PMID:8060912