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Anti-Human DSC2 Antibody (SAA1658)

Catalog #:   RHF94101 Specific References (43) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: Q02487
Overview

Catalog No.

RHF94101

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Desmosomal glycoprotein II, Desmocollin-2, DSC2, DSC3, Cadherin family member 2, CDHF2, Desmosomal glycoprotein III, Desmocollin-3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q02487

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1658

Data Image
References

Immunohistopathological analyses of a case of pemphigus vegetans with antibodies against desmoglein 1 and desmocollins 1-3., PMID:39073162

Atypical pemphigus with anti-desmocollin 2 and 3 antibodies, initially presenting as pemphigus vulgaris with anti-desmoglein 3 antibodies., PMID:32808594

Paraneoplastic pemphigus associated with Waldenström's macroglobulinemia., PMID:32103535

The involvement of ADAM10 in acantholysis in mucocutaneous pemphigus vulgaris depends on the autoantibody profile of each patient., PMID:31370093

A systematic review and critical evaluation of immunohistochemical associations in hidradenitis suppurativa., PMID:31281635

Pemphigus herpetiformis with autoantibodies to desmocollins 1, 2 and 3., PMID:29333762

Routine detection of serum antidesmocollin autoantibodies is only useful in patients with atypical pemphigus., PMID:28815795

Desmoglein 2 regulates the intestinal epithelial barrier via p38 mitogen-activated protein kinase., PMID:28740231

Establishment of IgA ELISAs of mammalian recombinant proteins of human desmocollins 1-3., PMID:27150020

Oxidized low-density lipoprotein attenuated desmoglein 1 and desmocollin 2 expression via LOX-1/Ca(2+)/PKC-β signal in human umbilical vein endothelial cells., PMID:26498522

Detection of IgG antibodies to desmoglein 3 and desmocollins 2 and 3 in mucosal dominant-type pemphigus vulgaris with severe pharyngalgia and hyperemia of the bulbar conjunctiva., PMID:26463887

Clinical and immunological findings in 104 cases of paraneoplastic pemphigus., PMID:26358412

Anti-desmocollin autoantibodies in nonclassical pemphigus., PMID:25640111

Desmocollin-specific antibodies in a patient with Hailey-Hailey disease., PMID:25580559

Paraneoplastic pemphigus with eosinophilic spongiosis and autoantibodies against desmocollins 2 and 3., PMID:24635070

IgA/IgG pemphigus with infiltration of neutrophils and eosinophils in an ulcerative colitis patient., PMID:24604005

The expanding spectrum of IgA pemphigus: a case report and review of the literature., PMID:24601812

Desmosomal cadherins are decreased in explanted arrhythmogenic right ventricular dysplasia/cardiomyopathy patient hearts., PMID:24086444

Two cases of pemphigus vegetans with IgG anti-desmocollin 3 antibodies., PMID:23946009

IgA pemphigus with non-pustular erythematous lesions and IgA antibodies to desmocollins 1 and 2., PMID:23797684

Mesenchymal-epithelial transitions: spontaneous and cumulative syntheses of epithelial marker molecules and their assemblies to novel cell junctions connecting human hematopoietic tumor cells to carcinomatoid tissue structures., PMID:21647878

De novo desmin-mutation N116S is associated with arrhythmogenic right ventricular cardiomyopathy., PMID:20829228

Compound and digenic heterozygosity contributes to arrhythmogenic right ventricular cardiomyopathy., PMID:20152563

Autoantibodies against desmocollins in European patients with pemphigus., PMID:19456767

Desmoglein-2: a novel regulator of apoptosis in the intestinal epithelium., PMID:17804817

The area composita of adhering junctions connecting heart muscle cells of vertebrates - III: assembly and disintegration of intercalated disks in rat cardiomyocytes growing in culture., PMID:17275137

Desmosome-binding antibody KM48 recognises an extracellular antigen different from desmosomal cadherins Dsg 1-3 and Dsc 1-3., PMID:15757816

The detection of IgG and IgA autoantibodies to desmocollins 1-3 by enzyme-linked immunosorbent assays using baculovirus-expressed proteins, in atypical pemphigus but not in typical pemphigus., PMID:15270874

Molecular characterization of desmosomes in meningiomas and arachnoidal tissue., PMID:12845453

Comparative study of autoantigen profile between Colombian and Brazilian types of endemic pemphigus foliaceus by various biochemical and molecular biological techniques., PMID:12788527

Identification of desmoglein 1 as autoantigen in a patient with intraepidermal neutrophilic IgA dermatosis type of IgA pemphigus., PMID:10839721

Expression of a single pair of desmosomal glycoproteins renders the corneal epithelium unique amongst stratified epithelia., PMID:10634593

Diversity of desmosomal proteins in regenerating epidermis: immunohistochemical study using a human skin organ culture model., PMID:10482015

Compositionally different desmosomes in the various compartments of the human hair follicle., PMID:9810708

Antisense expression of a desmocollin gene in MDCK cells alters desmosome plaque assembly but does not affect desmoglein expression., PMID:9716266

Human desmocollin 1 (Dsc1) is an autoantigen for the subcorneal pustular dermatosis type of IgA pemphigus., PMID:9242496

The differential expression of desmocollin isoforms in mammary epithelia., PMID:8878890

Distinct desmocollin isoforms occur in the same desmosomes and show reciprocally graded distributions in bovine nasal epidermis., PMID:8755539

The desmocollins of human foreskin epidermis: identification and chromosomal assignment of a third gene and expression patterns of the three isoforms., PMID:7665906

A case of pemphigus vulgaris showing reactivity with pemphigus antigens (Dsg1 and Dsg3) and desmocollins., PMID:7706774

Unusual acantholytic bullous dermatosis associated with neoplasia and IgG and IgA antibodies against bovine desmocollins I and II., PMID:8034804

The bovine desmocollin family: a new gene and expression patterns reflecting epithelial cell proliferation and differentiation., PMID:8034749

Detection of anti-desmocollins I and II autoantibodies in two cases of Hallopeau type pemphigus vegetans by immunoblot analysis., PMID:8060912

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Human DSC2 Antibody (SAA1658) [RHF94101]
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