Catalog No.
RHF39801
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Ras-related protein Rab-10, RAB10
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P61026
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1654
Cellular and subcellular localization of Rab10 and phospho-T73 Rab10 in the mouse and human brain., PMID:38110990
Alterations in the LRRK2-Rab pathway in urinary extracellular vesicles as Parkinson's disease and pharmacodynamic biomarkers., PMID:36750568
Evaluation of Current Methods to Detect Cellular Leucine-Rich Repeat Kinase 2 (LRRK2) Kinase Activity., PMID:35599495
Phosphoproteome Profiling of the Receptor Tyrosine Kinase MuSK Identifies Tyrosine Phosphorylation of Rab GTPases., PMID:35227894
Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain., PMID:35012605
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms., PMID:33459343
Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues., PMID:33105882
Trastuzumab-induced upregulation of a protein set in extracellular vesicles emitted by ErbB2-positive breast cancer cells correlates with their trastuzumab sensitivity., PMID:33023655
In vivo mapping of a GPCR interactome using knockin mice., PMID:32457152
Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation., PMID:32250352
Rab32 interacts with SNX6 and affects retromer-dependent Golgi trafficking., PMID:30640902
Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome., PMID:30582284
The pervasive effects of recombinant Fasciola gigantica Ras-related protein Rab10 on the functions of goat peripheral blood mononuclear cells., PMID:30400957
The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human., PMID:29743203
Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease., PMID:29562525
Back to the future: new target-validated Rab antibodies for evaluating LRRK2 signalling in cell biology and Parkinson's disease., PMID:29305429
Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag., PMID:29286425
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase., PMID:29127256
Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils., PMID:29127255
Systematic investigation on the intracellular trafficking network of polymeric nanoparticles., PMID:28225130
'Up with the LRRK': a phosphorylated Rab10 assay for evaluation of LRRK2 activity and inhibitor engagement., PMID:27621483
Evaluation of global differential gene and protein expression in primary Pterygium: S100A8 and S100A9 as possible drivers of a signaling network., PMID:24825356
Functional analysis of novel Rab GTPases identified in the proteome of purified Legionella-containing vacuoles from macrophages., PMID:24373249
Analyzing the function of small GTPases by microinjection of plasmids into polarized epithelial cells., PMID:21673637
Identification and characterisation of novel Mss4-binding Rab GTPases., PMID:21194374
Rab10 associates with primary cilia and the exocyst complex in renal epithelial cells., PMID:20576682
Chlamydia pneumoniae inclusion membrane protein Cpn0585 interacts with multiple Rab GTPases., PMID:17908815
Rab10 regulates membrane transport through early endosomes of polarized Madin-Darby canine kidney cells., PMID:16641372
Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells., PMID:10887961
Analysis of rab10 localization in sea urchin embryonic cells by three-dimensional reconstruction., PMID:9716447
Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag., PMID:7688123
For research use only. Not for human or drug use.
