Anti-Human CLDN2 Antibody (SAA1651)

Catalog No.

RHF23701

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

CLDN2, SP82, Claudin-2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P57739

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1651

Claudin-2 simplifies histological assessment of activity/remission of ulcerative colitis in real-life daily practice., PMID:39975995

Claudins and Gastric Cancer: An Overview., PMID:35053454

Tight junction protein claudin-2 promotes cell entry of Bombyx mori cypovirus., PMID:34324010

Sex-dependent modulation of immune development in mice by secretory IgA-coated Lactobacillus reuteri isolated from breast milk., PMID:33612242

HMGB1 enhances epithelial permeability via p63/TGF-β signaling in lung and terminal bronchial epithelial cells., PMID:32857676

Tight junction proteins in gastrointestinal and liver disease., PMID:30297438

Safety evaluation of a human chimeric monoclonal antibody that recognizes the extracellular loop domain of claudin-2., PMID:29448044

Treatment-related survival associations of claudin-2 expression in fibroblasts of colorectal cancer., PMID:29134439

Acanthamoeba (T4) trophozoites cross the MDCK epithelium without cell damage but increase paracellular permeability and transepithelial resistance by modifying tight junction composition., PMID:29097064

Creation of a Claudin-2 Binder and Its Tight Junction-Modulating Activity in a Human Intestinal Model., PMID:28928120

Claudin-1 Protein Expression Is a Good Prognostic Factor in Non-Small Cell Lung Cancer, but only in Squamous Cell Carcinoma Cases., PMID:27687058

Oxidative stress induces claudin-2 nitration in experimental type 1 diabetic nephropathy., PMID:24726862

A novel microfluidics-based method for probing weak protein-protein interactions., PMID:22641189

Increase in claudin-2 expression by an EGFR/MEK/ERK/c-Fos pathway in lung adenocarcinoma A549 cells., PMID:22546605

Proteopolymersomes: in vitro production of a membrane protein in polymersome membranes., PMID:22239807

Claudin-2 is selectively enriched in and promotes the formation of breast cancer liver metastases through engagement of integrin complexes., PMID:21076473

Symplekin promotes tumorigenicity by up-regulating claudin-2 expression., PMID:20133805

Differential expression of claudin tight junction proteins in the human cortical nephron., PMID:20124215

[Study of claudins and prognostic factors in some gastrointestinal diseases]., PMID:20071310

The protective effect of alpha-tocopherol against dichromate-induced renal tight junction damage is mediated via ERK1/2., PMID:19766176

Molecular basis for cation selectivity in claudin-2-based pores., PMID:19538287

TNFalpha up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling., PMID:19214581

Changes in the expression of claudins in active ulcerative colitis., PMID:19120888

Epidermal growth factor receptor and claudin-2 participate in A549 permeability and remodeling: implications for non-small cell lung cancer tumor colonization., PMID:18942115

Expression of claudin-2 in the multistage process of gastric carcinogenesis., PMID:18366005

Dynamics of enterocyte tight junctions: effect of experimental colitis and two different anti-TNF strategies., PMID:18258792

Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation., PMID:17971210

Oncostatin M-induced effects on EMT in human proximal tubular cells: differential role of ERK signaling., PMID:17881458

Opposing regulation of the tight junction protein claudin-2 by interferon-gamma and interleukin-4., PMID:17640674

Distinct claudin expression profile in histologic subtypes of lung cancer., PMID:17418912

Amyloid beta-peptide1-42 alters tight junction protein distribution and expression in brain microvessel endothelial cells., PMID:16644119

Altered localization and expression of tight-junction proteins in a rat model with chronic acid reflux esophagitis., PMID:16143882

Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier., PMID:16039564

Increased expression of claudins in cervical squamous intraepithelial neoplasia and invasive carcinoma., PMID:15754293

Claudins 2, 3, 4, and 5 in Paget's disease and breast carcinoma., PMID:15619213

Tight junction proteins ZO-1, occludin, and claudins in developing and adult human perineurium., PMID:15258179

Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells., PMID:12432083

The renal segmental distribution of claudins changes with development., PMID:12110008

Claudin-2 is selectively expressed in proximal nephron in mouse kidney., PMID:11592954

Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut., PMID:11159882

Organization of choroid plexus epithelial and endothelial cell tight junctions and regulation of claudin-1, -2 and -5 expression by protein kinase C., PMID:10841351

Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier., PMID:10508866

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands., PMID:9892664

Document Download

Anti-Human CLDN2 Antibody (SAA1651).pdf