Macrophage activation determines muscle wasting in pancreatic cancer., PMID:40442475
CSF proteomics of semorinemab Alzheimer's disease trials identifies cell-type specific signatures., PMID:40435316
Anti-CHI3L1 antibody suppresses colon cancer growth through downregulation of VEGFA and NAMPT expression., PMID:40377878
Anti-arthritis Effect of Anti-chitinase-3-like 1 Antibody Through Inhibition of MMP3., PMID:40342842
Chitinase 3-like protein 1 deficiency ameliorates drug-induced acute liver injury by inhibition of neutrophil recruitment through lipocalin-2., PMID:40196357
Combination therapy with Chicoric acid and PD-1/PD-L1 blockade improves the immunotherapy response in patient-derived ovarian cancer xenograft model., PMID:40087780
Biological signatures in the Alzheimer's continuum discriminate between diagnosis-related and -unrelated associations to ATN categories., PMID:40046342
Omics data integration analysis identified new biological insights into chronic antibody-mediated rejection (CAMR)., PMID:39979925
Targeting of Ykl-40 as a Protumor in Personalized Medicine: A New Dimension in Disease Understanding., PMID:39976089
Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications., PMID:39827337
Chitinase-3-like Protein 1 Reduces the Stability of Atherosclerotic Plaque via Impairing Macrophagic Efferocytosis., PMID:39813006
Activated kynurenine pathway metabolism by YKL-40 establishes an inhibitory immune microenvironment and drives glioblastoma development., PMID:39718635
Novel Interacting Partners of MGP-40, a Chitinase-Like Protein in Buffalo Mammary Epithelial Cells., PMID:39579292
Pharmacodynamic effects of semorinemab on plasma and CSF biomarkers of Alzheimer's disease pathophysiology., PMID:39513754
BTK and YKL-40 Levels and Their Association with Acute AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder., PMID:39485631
Cohort study of serological biomarkers for interstitial lung disease in patients with rheumatoid arthritis., PMID:39450495
Predictive and Dynamic Signature for Antiangiogenics in Combination with a PD1 Inhibitor in Soft-Tissue Sarcoma: Correlative Studies Linked to the IMMUNOSARC Trial., PMID:39283727
Predictive value of serum HIF-1α/HIF-2α and YKL-40 levels for vascular invasion and prognosis of follicular thyroid cancer., PMID:39277981
Chitinase 3-like-1 (CHI3L1) in the pathogenesis of epidermal growth factor receptor mutant non-small cell lung cancer., PMID:39178575
Primate cerebrospinal fluid CHI3L1 reflects brain TREM2 agonism., PMID:39090679
Discovery of crucial cytokines associated with deep vein thrombus formation by protein array analysis., PMID:39026176
Predictive potential of serum and cerebrospinal fluid biomarkers for disease activity in treated multiple sclerosis patients., PMID:38909525
A humanized Anti-YKL-40 antibody inhibits tumor development., PMID:38824968
Fully human chitinase-3 like-1 monoclonal antibody inhibits tumor growth, fibrosis, angiogenesis, and immune cell remodeling in lung, pancreatic, and colorectal cancers., PMID:38820971
Anti-chitinase-3-like 1 antibody attenuated atopic dermatitis-like skin inflammation through inhibition of STAT3-dependent CXCL8 expression., PMID:38745399
Changes in metabolic parameters and serum YKL-40 levels in Chinese rheumatoid arthritis patients during tocilizumab therapy., PMID:38696116
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial., PMID:38683602
Chitin-mediated blockade of chitinase-like proteins reduces tumor immunosuppression, inhibits lymphatic metastasis and enhances anti-PD-1 efficacy in complementary TNBC models., PMID:38605414
Location-based prediction model for Crohn's disease regarding a novel serological marker, anti-chitinase 3-like 1 autoantibodies., PMID:38075846
The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer., PMID:38039967
The potential roles and mechanisms of Chitinase-3-like-1 in the pathogenesis of type 2-biased airway diseases., PMID:38036279
Clinically isolated syndrome: Diagnosis and risk of developing clinically definite multiple sclerosis., PMID:37858891
Chitinase-3-like 1 regulates TH2 cells, TFH cells and IgE responses to helminth infection., PMID:37575256
Deciphering the Action of Neuraminidase in Glioblastoma Models., PMID:37511403
Chitinase 3-Like-1 Expression Is Upregulated Under Inflammatory Conditions in Human Oral Epithelial Cells., PMID:37380444
Chi3l1 Is a Modulator of Glioma Stem Cell States and a Therapeutic Target in Glioblastoma., PMID:37101376
CHI3L1 in the CSF is a potential biomarker for anti-leucine-rich glioma inactivated 1 encephalitis., PMID:36685530
A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice., PMID:36683763
CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axis., PMID:36618349
Oligoclonal band versus chitinase-3-like protein-1 in CSF of newly diagnosed relapsing remitting multiple sclerosis., PMID:36591957
Serum CHI3L1 as a Biomarker for Non-invasive Diagnosis of Liver Fibrosis., PMID:36274212
Host chitinase 3-like-1 is a universal therapeutic target for SARS-CoV-2 viral variants in COVID-19., PMID:35735790
Targeting Chitinase 1 and Chitinase 3-Like 1 as Novel Therapeutic Strategy of Pulmonary Fibrosis., PMID:35370755
High Levels of Cerebrospinal Fluid Kappa Free Light Chains Relate to IgM Intrathecal Synthesis and Might Have Prognostic Implications in Relapsing Multiple Sclerosis., PMID:35330910
Host Chitinase 3-like-1 is a Universal Therapeutic Target for SARS-CoV-2 Viral Variants in COVID 19., PMID:35118470
Anti-TNF Agents Restrict Adherent-invasive Escherichia coli Replication Within Macrophages Through Modulation of Chitinase 3-like 1 in Patients with Crohn's Disease., PMID:35022663
Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy., PMID:34987649
Chitinase 3-like 1 secreted from cancer-associated fibroblasts promotes tumor angiogenesis via interleukin-8 secretion in colorectal cancer., PMID:34913066
Anti-Chi3L1 antibody suppresses lung tumor growth and metastasis through inhibition of M2 polarization., PMID:34861103
Paralysis of the cytotoxic granule machinery is a new cancer immune evasion mechanism mediated by chitinase 3-like-1., PMID:34824159
For research use only. Not for human or drug use.
