Anti-Human RYK Antibody (SAA1631)

Catalog No.

RHE05601

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Tyrosine-protein kinase RYK, RYK, JTK5A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P34925

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1631

The potential role of RhoA/ROCK-inhibition on locomotor recovery after spinal cord injury: a systematic review of in-vivo studies., PMID:39956860

Protein Biomarkers of Adverse Clinical Features and Events in Sarcomeric Hypertrophic Cardiomyopathy., PMID:39498543

MAdCAM-1 co-stimulation combined with retinoic acid and TGF-β induces blood CD8+ T cells to adopt a gut CD101+ TRM phenotype., PMID:38729611

The Notch1 signaling pathway directly modulates the human RANKL-induced osteoclastogenesis., PMID:38040752

Complexity of progranulin mechanisms of action in mesothelioma., PMID:36471440

Periodontal ligaments enhance neurite outgrowth in trigeminal ganglion neurons through Wnt5a production induced by mechanical stimulation., PMID:36374171

Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study., PMID:35152886

Planar cell polarity signaling components are a direct target of β-amyloid-associated degeneration of glutamatergic synapses., PMID:34407949

Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates., PMID:33554060

Renal intravascular large B-cell lymphoma predominantly localized in peritubular capillaries., PMID:33537904

Non-Canonical WNT5A Signaling Through RYK Contributes to Aggressive Phenotype of the Rheumatoid Fibroblast-Like Synoviocytes., PMID:33178184

Wnt5b/Ryk-mediated membrane trafficking of P2X3 receptors contributes to bone cancer pain., PMID:32979370

Interplay between axonal Wnt5-Vang and dendritic Wnt5-Drl/Ryk signaling controls glomerular patterning in the Drosophila antennal lobe., PMID:32357156

Wnt-11 as a Potential Prognostic Biomarker and Therapeutic Target in Colorectal Cancer., PMID:31261741

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α4β7., PMID:30153309

Targeting Wnt signaling pseudokinases in hematological cancers., PMID:29989208

MAdCAM costimulation through Integrin-α4β7 promotes HIV replication., PMID:29875402

Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120., PMID:29463753

Ryk receptors on unmyelinated nerve fibers mediate excitatory synaptic transmission and CCL2 release during neuropathic pain induced by peripheral nerve injury., PMID:28565999

Neutralizing and Targeting Properties of a New Set of α4β7-Specific Antibodies Are Influenced by Their Isotype., PMID:28177967

Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy., PMID:27738167

Ryk controls remapping of motor cortex during functional recovery after spinal cord injury., PMID:27065364

Wnt/Ryk signaling contributes to neuropathic pain by regulating sensory neuron excitability and spinal synaptic plasticity in rats., PMID:26407042

Human epicardial cell-conditioned medium contains HGF/IgG complexes that phosphorylate RYK and protect against vascular injury., PMID:26025956

Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2-V3 interaction and modulates neutralization sensitivity., PMID:24569807

A fully human inhibitory monoclonal antibody to the Wnt receptor RYK., PMID:24058687

Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B., PMID:23979591

Ryk, a receptor regulating Wnt5a-mediated neurogenesis and axon morphogenesis of ventral midbrain dopaminergic neurons., PMID:23517308

Wnt5a regulates midbrain dopaminergic axon growth and guidance., PMID:21483795

The genotype of early-transmitting HIV gp120s promotes α (4) β(7)-reactivity, revealing α (4) β(7) +/CD4+ T cells as key targets in mucosal transmission., PMID:21383973

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1., PMID:19933330

Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury., PMID:19473059

Repulsive Wnt signaling inhibits axon regeneration after CNS injury., PMID:18701700

HIV envelope binding by macrophage-expressed gp340 promotes HIV-1 infection., PMID:18641344

Influence of polymorphic metabolic enzymes on biotransformation and effects of diphenylmethane diisocyanate., PMID:17676332

WNT signaling pathway and stem cell signaling network., PMID:17634527

Cryoelectron tomographic analysis of an HIV-neutralizing protein and its complex with native viral gp120., PMID:17599917

HIV-1 gp120 inhibits TLR9-mediated activation and IFN-{alpha} secretion in plasmacytoid dendritic cells., PMID:17360657

Structural definition of a conserved neutralization epitope on HIV-1 gp120., PMID:17301785

STAT3-induced WNT5A signaling loop in embryonic stem cells, adult normal tissues, chronic persistent inflammation, rheumatoid arthritis and cancer (Review)., PMID:17203201

Probing the functional heterogeneity of surface binding sites by analysis of experimental binding traces and the effect of mass transport limitation., PMID:17158569

Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract., PMID:16116452

Enhanced immunogenicity of gp120 protein when combined with recombinant DNA priming to generate antibodies that neutralize the JR-FL primary isolate of human immunodeficiency virus type 1., PMID:15919951

Targeted lysis of HIV-infected cells by natural killer cells armed and triggered by a recombinant immunoglobulin fusion protein: implications for immunotherapy., PMID:15680414

Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions., PMID:14967033

Salivary agglutinin inhibits HIV type 1 infectivity through interaction with viral glycoprotein 120., PMID:12689412

[Simultaneous detection of hepatitis B virus surface antigen (HBsAg) and hepatitis C virus (HCV) related antibodies by an immunochromatographic test method using synthesized oligonucleotide-bound protein probes, OligoFast]., PMID:12542392

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites., PMID:12478295

Biosensor analysis of dynamics of interleukin 5 receptor subunit beta(c) interaction with IL5:IL5R(alpha) complexes., PMID:12202242

Beta-turn Phe in HIV-1 Env binding site of CD4 and CD4 mimetic miniprotein enhances Env binding affinity but is not required for activation of co-receptor/17b site., PMID:12033937

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