Identification of antibody-drug conjugate payloads which are substrates of ATP-binding cassette drug efflux transporters., PMID:40501953
In vitro models to evaluate multidrug resistance in cancer cells: Biochemical and morphological techniques and pharmacological strategies., PMID:39363148
FXR, MRP-1 and SLC7A5: New Targets for the Treatment of Hepatocellular Carcinoma., PMID:39194338
Possible New Histological Prognostic Index for Large B-Cell Lymphoma., PMID:37834968
Recent Advances in Photothermal Therapies Against Cancer and the Role of Membrane Transporter Modulators on the Efficacy of This Approach., PMID:37138532
Anti-proliferative effect of melatonin in human hepatoma HepG2 cells occurs mainly through cell cycle arrest and inflammation inhibition., PMID:36928762
Anti-drug resistance, anti-inflammation, and anti-proliferation activities mediated by melatonin in doxorubicin-resistant hepatocellular carcinoma: in vitro investigations., PMID:36651944
Bilirubin level is decreased in patients with allergic rhinitis., PMID:36470582
Combinatory therapy of MRP1-targeted photoimmunotherapy and liposomal doxorubicin promotes the antitumor effect for chemoresistant small cell lung cancer., PMID:35931394
LncRNA SNHG11 enhances bevacizumab resistance in colorectal cancer by mediating miR-1207-5p/ABCC1 axis., PMID:35324517
Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo., PMID:34386326
PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies., PMID:33879555
MDR1 protein (ABC-C1) Over Expression in Giardia Intestinalis Incubated with Albendazole and Nitazoxanide., PMID:33840056
Combination efficacy of pertuzumab and trastuzumab for trastuzumab emtansine-resistant cells exhibiting attenuated lysosomal trafficking or efflux pumps upregulation., PMID:32997196
FcRn Overexpression Expands Diversity of the Humoral Immune Response in bFcRn Transgenic Mice., PMID:32973781
In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta., PMID:32915249
The Effect of Nanosystems on ATP-Binding Cassette Transporters: Understanding the Influence of Nanosystems on Multidrug Resistance Protein-1 and P-glycoprotein., PMID:32290047
Label-free quantitative identification of abnormally ubiquitinated proteins as useful biomarkers for human lung squamous cell carcinomas., PMID:32140187
Cell proliferation and invasion are regulated differently by EGFR and MRP1 in T-DM1-resistant breast cancer cells., PMID:31704984
Cytosolic delivery of inhibitory antibodies with cationic lipids., PMID:31611380
Beta1 integrin blockade overcomes doxorubicin resistance in human T-cell acute lymphoblastic leukemia., PMID:31043590
Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells., PMID:30315846
Efflux Pump Substrates Shuttled to Cytosolic or Vesicular Compartments Exhibit Different Permeability in a Quantitative Human Blood-Brain Barrier Model., PMID:30212633
A systems medicine approach reveals disordered immune system and lipid metabolism in multiple sclerosis patients., PMID:29194580
Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human development., PMID:28912477
MRP1 protein expression in leukemic stem cells as a negative prognostic marker in acute myeloid leukemia patients., PMID:28805931
Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar., PMID:27926506
Sequences in Linker-1 domain of the multidrug resistance associated protein (MRP1 or ABCC1) bind to tubulin and their binding is modulated by phosphorylation., PMID:27908733
Up-regulation of glutathione-related genes, enzyme activities and transport proteins in human cervical cancer cells treated with doxorubicin., PMID:27424321
Arsenic Triglutathione [As(GS)3] Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) Is Selectively Modified by Phosphorylation of Tyr920/Ser921 and Glycosylation of Asn19/Asn23., PMID:27297967
Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma., PMID:26548759
Cetuximab enhanced the efficacy of chemotherapeutic agent in ABCB1/P-glycoprotein-overexpressing cancer cells., PMID:26506420
Selection of resistant acute myeloid leukemia SKM-1 and MOLM-13 cells by vincristine-, mitoxantrone- and lenalidomide-induced upregulation of P-glycoprotein activity and downregulation of CD33 cell surface exposure., PMID:26002042
Association of NADPH oxidase polymorphisms with anthracycline-induced cardiotoxicity in the RICOVER-60 trial of patients with aggressive CD20(+) B-cell lymphoma., PMID:25823784
Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatments., PMID:25646013
RNAi-based knockdown of multidrug resistance-associated protein 1 is sufficient to reverse multidrug resistance of human lung cells., PMID:25605145
Exploration of interactions between membrane proteins embedded in supported lipid bilayers and their antibodies by reflectometric interference spectroscopy-based sensing., PMID:25270526
Immunolocalization of ABC drug transporters in human placenta from normal and gestational diabetic pregnancies., PMID:25029804
Resistance and intolerance to statins., PMID:24996502
Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1., PMID:24937702
WHI-P154 enhances the chemotherapeutic effect of anticancer agents in ABCG2-overexpressing cells., PMID:24903205
Correlation of Nrf2, NQO1, MRP1, cmyc and p53 in colorectal cancer and their relationships to clinicopathologic features and survival., PMID:24695690
Modulation of ABCC1 and ABCG2 proteins by ouabain in human breast cancer cells., PMID:24596392
Differential functional rescue of Lys(513) and Lys(516) processing mutants of MRP1 (ABCC1) by chemical chaperones reveals different domain-domain interactions of the transporter., PMID:24231430
Parguerenes: Marine red alga bromoditerpenes as inhibitors of P-glycoprotein (ABCB1) in multidrug resistant human cancer cells., PMID:23415901
BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo., PMID:23046348
Inhibition of the MRP1-mediated transport of the menadione-glutathione conjugate (thiodione) in HeLa cells as studied by SECM., PMID:22679290
Induction of DNA strand breaks is critical to predict the cytotoxicity of gemtuzumab ozogamicin against leukemic cells., PMID:22632031
CD40 stimulation induces vincristine resistance via AKT activation and MRP1 expression in a human multiple myeloma cell line., PMID:22445357
Tyrosine kinase inhibitors influence ABCG2 expression in EGFR-positive MDCK BCRP cells via the PI3K/Akt signaling pathway., PMID:22354538
For research use only. Not for human or drug use.
